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A specific antibody to detect transcription factor T-Pit: a reliable marker of corticotroph cell differentiation and a tool to improve the classification of pituitary neuroendocrine tumours

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References

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Acknowledgements

This work was supported by The Swedish Cancer Society, Knut and Alice Wallenberg foundation and ALF-funding from the Uppsala University Hospital in Uppsala.

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Authors and Affiliations

  1. Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, Sweden

    Evelina Sjöstedt & Jan Mulder

  2. Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

    Evelina Sjöstedt, Cecilia Lindskog, Fredrik Pontén & Olivera Casar-Borota

  3. Department of Specialized Endocrinology, Rikshospitalet, Oslo University Hospital, Oslo, Norway

    Jens Bollerslev

  4. Faculty of Medicine, University of Oslo, Oslo, Norway

    Jens Bollerslev

  5. Department of Clinical Pathology, Uppsala University Hospital, Uppsala, Sweden

    Fredrik Pontén & Olivera Casar-Borota

  6. Department of Pathology, Oslo University Hospital, Oslo, Norway

    Olivera Casar-Borota

Authors
  1. Evelina Sjöstedt
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  2. Jens Bollerslev
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  3. Jan Mulder
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  4. Cecilia Lindskog
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  5. Fredrik Pontén
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  6. Olivera Casar-Borota
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Corresponding author

Correspondence to Olivera Casar-Borota.

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Conflict of interest

Fredrik Pontén is a co-founder of Atlas Antibodies. The other authors have no conflicts of interest to disclose.

Ethical standards

All patients whose tumour tissues have been used in the study provided written informed consent, and the regional ethical committee approved the project.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (DOCX 17 kb)

Appendix

Appendix

A new version of the Human Protein Atlas is released annually. The next version will include full protein profiling and validation data for the HPA072686 antibody; thereafter, this antibody will also become available through Atlas Antibodies (Stockholm, Sweden).

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Sjöstedt, E., Bollerslev, J., Mulder, J. et al. A specific antibody to detect transcription factor T-Pit: a reliable marker of corticotroph cell differentiation and a tool to improve the classification of pituitary neuroendocrine tumours. Acta Neuropathol 134, 675–677 (2017). https://doi.org/10.1007/s00401-017-1768-9

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  • DOI: https://doi.org/10.1007/s00401-017-1768-9

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