Skip to main content
SpringerLink
Log in

Pituitary prolactinoma with T cell rich inflammatory infiltrate: a possible example of antitumoral immune response to be differentiated from lymphocytic hypophysitis

  • Letter to the Editor
  • Published:
Acta Neuropathologica Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Bodey B, Bodey B Jr, Kaiser HE (1997) Dendritic type, accessory cells within the mammalian thymic microenvironment. Antigen presentation in the dendritic neuro-endocrine-immune cellular network. In Vivo 11:351–370

    PubMed  CAS  Google Scholar 

  2. De Bellis A, Bizzarro A, Pivonello R, Lombardi G, Bellastella A (2005) Prolactin and autoimmunity. Pituitary 8:25–30

    Article  PubMed  CAS  Google Scholar 

  3. Gutenberg A, Buslei R, Fahlbusch R, Buchfelder M, Bruck W (2005) Immunopathology of primary hypophysitis. Implications for pathogenesis. Am J Surg Pathol 29:329–338

    Article  PubMed  CAS  Google Scholar 

  4. Holck S, Laursen H (1983) Prolactinoma coexistent with granulomatous hypophysitis. Acta Neuropathol 61:253–257

    Article  PubMed  CAS  Google Scholar 

  5. Horvath E, Vidal S, Syro LV, Kovacs K, Smyth HS, Uribe H (2001) Severe lymphocytic adenohypophysitis with selective disappearance of prolactin cells: a histologic, ultrastructural and immunoelectron microscopic study. Acta Neuropathol 101:631–637

    PubMed  CAS  Google Scholar 

  6. Kontogeorgos G, Horvath E, Kovacs K, Coire C, Lloyd RV, Scheithauer BW, Smyth HS (2006) Morphologic changes of prolactin-producing pituitary adenomas after short treatment with dopamine agonists. Acta Neuropathol 111:46–52

    Article  PubMed  Google Scholar 

  7. Leung GKK, Lopes MBS, Thorner MO, Vance ML, Laws ER Jr (2004) Primary hypophysitis: a single center experience in 16 cases. J Neurosurg 101:262–271

    Article  PubMed  Google Scholar 

  8. McConnon JK, Smyth HS, Horvath E (1991) A case of sparsely granulated growth hormone cell adenoma associated with lymphocytic hypophysitis. J Endocrinol Invest 14:691–696

    PubMed  CAS  Google Scholar 

  9. Paulus W, Honegger J, Keyvani K, Fahlbusch R (1999) Xanthogranuloma of the sellar region: a clinicopathological entity different from adamantinomatous craniopharyngioma. Acta Neuropathol 97:377–382

    Article  PubMed  CAS  Google Scholar 

  10. Sautner D, Saeger W, Ludecke DK, Jansen V, Puchner MJ (1995) Hypophysitis in surgical and autoptical specimens. Acta Neuropathol 90:637–644

    Article  PubMed  CAS  Google Scholar 

  11. Ueta Y, Levy A, Chowdrey HS, Lightman SL (1995) S-100 antigen-positive folliculostellate cells are not the source of IL-6 gene expression in human pituitary adenomas. J Neuroendocrinol 7:467–474

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Pathology, University of Bern, Murtenstrasse 31, Postfach 62, 3010, Bern, Switzerland

    Istvan Vajtai & Andreas Kappeler

  2. Department of Endocrinology, University Hospital Bern, Bern, Switzerland

    Rahel Sahli

Authors
  1. Istvan Vajtai
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Rahel Sahli
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Andreas Kappeler
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Istvan Vajtai.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vajtai, I., Sahli, R. & Kappeler, A. Pituitary prolactinoma with T cell rich inflammatory infiltrate: a possible example of antitumoral immune response to be differentiated from lymphocytic hypophysitis. Acta Neuropathol 111, 397–399 (2006). https://doi.org/10.1007/s00401-006-0065-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00401-006-0065-9

Keywords

Search

Navigation