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Primary anastomosis with a defunctioning stoma versus Hartmann's procedure for perforated diverticulitis—a comparison of stoma reversal rates

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Abstract

Purpose

The ideal treatment of patients with perforated diverticulitis is still controversial. Hartmann's procedure has been the treatment of choice for decades, but primary anastomosis with a defunctioning stoma has become an accepted alternative. The aim of this study was to evaluate the stoma reversal rates after these two surgical strategies.

Methods

A retrospective review of the data from patients with perforated sigmoid diverticulitis between 2002 and 2011 undergoing a Hartmann's procedure (HP) versus a primary anastomosis with a defunctioning stoma (PA) was performed. Additionally, patients were contacted by mail or telephone in March 2012 using a standardized questionnaire.

Results

A total of 98 patients were identified: 72 undergoing HP and 26 patients receiving PA. The median follow-up time was 63 months (range 4–118). Whilst 85 % of patients with PA have had their stoma reversed, only 58 % of patients with an HP had a stoma reversal (p = 0.046). The median period until stoma reversal was significantly longer for HP (19 weeks) than for PA (12 weeks; p = 0.03). The 30-day mortality for PA was 12 % as opposed to 25 % for HP (p = 0.167). According to the Clavien–Dindo classification, surgical complications occurred significantly less frequently in patients with PA (p = 0.014).

Conclusion

The stoma reversal rates for PA are significantly higher than for HP. Thus, depending on the overall clinical situation, primary resection and anastomosis with a proximal defunctioning stoma might be the optimal procedure for selected patients with perforated diverticular disease.

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References

  1. Holmer C, Lehmann KS, Engelmann S, Grone J, Buhr HJ, Ritz JP (2011) Long-term outcome after conservative and surgical treatment of acute sigmoid diverticulitis. Langenbecks Arch Surg 396(6):825–832

    Article  PubMed  Google Scholar 

  2. Jun S, Stollman N (2002) Epidemiology of diverticular disease. Best Pract Res Clin Gastroenterol 16(4):529–542

    Article  PubMed  Google Scholar 

  3. Jacobs DO (2007) Diverticulitis. N Engl J Med 357(20):2057–2066

    Article  CAS  PubMed  Google Scholar 

  4. Makela JT, Kiviniemi HO, Laitinen ST (2010) Spectrum of disease and outcome among patients with acute diverticulitis. Dig Surg 27(3):190–196

    Article  PubMed  Google Scholar 

  5. Humes DJ, Solaymani-Dodaran M, Fleming KM, Simpson J, Spiller RC, West J (2009) A population-based study of perforated diverticular disease incidence and associated mortality. Gastroenterology 136(4):1198–1205

    Article  PubMed  Google Scholar 

  6. Biondo S, Perea MT, Rague JM, Pares D, Jaurrieta E (2001) One-stage procedure in non-elective surgery for diverticular disease complications. Color Dis 3(1):42–45

    Article  CAS  Google Scholar 

  7. Andersen JC, Bundgaard L, Elbrond H, Laurberg S, Walker LR, Stovring J (2012) Danish national guidelines for treatment of diverticular disease. Dan Med J 59(5):C4453

    PubMed  Google Scholar 

  8. Afshar S, Kurer MA (2012) Laparoscopic peritoneal lavage for perforated sigmoid diverticulitis. Color Dis 14(2):135–142

    Article  CAS  Google Scholar 

  9. Hold M, Denck H, Bull P (1990) Surgical management of perforating diverticular disease in Austria. Int J Color Dis 5(4):195–199

    Article  CAS  Google Scholar 

  10. Drumm J, Clain A (1984) The management of acute colonic diverticulitis with suppurative peritonitis. Ann R Coll Surg Engl 66(2):90–91

    CAS  PubMed  Google Scholar 

  11. Abbas S (2007) Resection and primary anastomosis in acute complicated diverticulitis, a systematic review of the literature. Int J Color Dis 22(4):351–357

    Article  Google Scholar 

  12. Khosraviani K, Campbell WJ, Parks TG, Irwin ST (2000) Hartmann procedure revisited. Eur J Surg 166(11):878–881

    Article  CAS  PubMed  Google Scholar 

  13. Oberkofler CE, Rickenbacher A, Raptis DA, Lehmann K, Villiger P, Buchli C, Grieder F, Gelpke H, Decurtins M, Tempia-Caliera AA, Demartines N, Hahnloser D, Clavien PA, Breitenstein S (2012) A Multicenter randomized clinical trial of primary anastomosis or Hartmann's procedure for perforated left colonic diverticulitis with purulent or fecal peritonitis. Ann Surg 256(5):819–827

    Article  PubMed  Google Scholar 

  14. Charbonnet P, Gervaz P, Andres A, Bucher P, Konrad B, Morel P (2008) Results of emergency Hartmann's operation for obstructive or perforated left-sided colorectal cancer. World J Surg Oncol(6)

  15. van de Wall BJM, Draaisma WA, Schouten ES, Broeders IAMJ, Consten ECJ (2010) Conventional and laparoscopic reversal of the Hartmann procedure: a review of literature. J Gastrointest Surg 14(4):743–752

    Article  PubMed  Google Scholar 

  16. Salem L, Flum DR (2004) Primary anastomosis or Hartmann's procedure for patients with diverticular peritonitis? A systematic review. Dis Colon Rectum 47(11):1953–1964

    Article  PubMed  Google Scholar 

  17. Belding III HH (1957) Acute perforated diverticulitis of the sigmoid colon with generalized peritonitis. AMA Arch Surg 74(4):511–515

    Article  Google Scholar 

  18. Underwood JW, Marks CG (1984) The septic complications of sigmoid diverticular-disease. Br J Surg 71(3):209–211

    Article  CAS  PubMed  Google Scholar 

  19. Medina VA, Papanicolaou GK, Tadros RR, Fielding LP (1991) Acute perforated diverticulitis: primary resection and anastomosis? Conn Med 55(5):258–261

    CAS  PubMed  Google Scholar 

  20. Wedell J, Banzhaf G, Chaoui R, Fischer R, Reichmann J (1997) Surgical management of complicated colonic diverticulitis. Br J Surg 84(3):380–383

    Article  CAS  PubMed  Google Scholar 

  21. Maggard MA, Chandler CF, Schmit PJ, Bennion RS, Hines OJ, Thompson JE (2001) Surgical diverticulitis: treatment options. Am Surg 67(12):1185–1189

    CAS  PubMed  Google Scholar 

  22. Regenet N, Pessaux P, Hennekinne S, Lermite E, Tuech JJ, Brehant O, Arnaud JP (2003) Primary anastomosis after intraoperative colonic lavage vs. Hartmann's procedure in generalized peritonitis complicating diverticular disease of the colon. Int J Color Dis 18(6):503–507

    Article  CAS  Google Scholar 

  23. Hoemke M, Treckmann J, Schmitz R, Shah S (1999) Complicated diverticulitis of the sigmoid: a prospective study concerning primary resection with secure primary anastomosis. Dig Surg 16(5):420–424

    Article  CAS  PubMed  Google Scholar 

  24. Constantinides VA, Heriot A, Remzi F, Darzi A, Senapati A, Fazio VW, Tekkis PP (2007) Operative strategies for diverticular peritonitis—a decision analysis between primary resection and anastomosis versus Hartmann's procedures. Ann Surg 245(1):94–103

    Article  PubMed  Google Scholar 

  25. Stocchi L (2010) Current indications and role of surgery in the management of sigmoid diverticulitis. World J Gastroenterol 16(7):804–817

    PubMed  Google Scholar 

  26. Vermeulen J, Coene PPLO, Van Hout NM, van der Harst E, Gosselink MP, Mannaerts GHH, Weidema WF, Lange JF (2009) Restoration of bowel continuity after surgery for acute perforated diverticulitis: should Hartmann's procedure be considered a one-stage procedure? Color Dis 11(6):619–624

    Article  CAS  Google Scholar 

  27. Hinchey EJ, Schaal PG, Richards GK (1978) Treatment of perforated diverticular disease of the colon. Adv Surg 12:85–109

    CAS  PubMed  Google Scholar 

  28. Linder MM, Wacha H, Feldmann U, Wesch G, Streifensand RA, Gundlach E (1987) The Mannheim peritonitis index—an instrument for the intraoperative prognosis of peritonitis. Chirurg 58(2):84–92

    CAS  PubMed  Google Scholar 

  29. Charlson ME, Charlson RE, Peterson JC, Marinopoulos SS, Briggs WM, Hollenberg JP (2008) The Charlson comorbidity index is adapted to predict costs of chronic disease in primary care patients. J Clin Epidemiol 61(12):1234–1240

    Article  PubMed  Google Scholar 

  30. Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications—a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213

    Article  PubMed  Google Scholar 

  31. Kourtesis GJ, Williams RA, Wilson SE (1988) Surgical options in acute diverticulitis—value of sigmoid resection in dealing with the septic focus. Aust N Z J Surg 58(12):955–959

    Article  CAS  PubMed  Google Scholar 

  32. Peoples JB, Vilk DR, Maguire JP, Elliott DW (1990) Reassessment of primary resection of the perforated segment for severe colonic diverticulitis. Am J Surg 159(3):291–293

    Article  CAS  PubMed  Google Scholar 

  33. Salem L, Anaya DA, Roberts KF, Flum DR (2005) Hartmann's colectomy and reversal in diverticulitis: a population-level assessment. Dis Colon Rectum 48(5):988–995

    Article  PubMed  Google Scholar 

  34. Wigmore SJ, Rainey JB (1995) Restoration of intestinal continuity following Hartmann's procedure: the Lothian Experience 1987–1992—reply. Br J Surg 82(8):1139

    Google Scholar 

  35. Aydin HN, Remzi FH, Tekkis PP, Fazio VW (2005) Hartmann's reversal is associated with high postoperative adverse events. Dis Colon Rectum 48(11):2117–2126

    Article  PubMed  Google Scholar 

  36. Gooszen AW, Gooszen HG, Veerman W, Van Dongen VM, Hermans J, Kranenbarg EK, Tollenaar RAEM (2001) Operative treatment of acute complications of diverticular disease: primary or secondary anastomosis after sigmoid resection. Eur J Surg 167(1):35–39

    Article  CAS  PubMed  Google Scholar 

  37. Gregg RO (1987) An ideal operation for diverticulitis of the colon. Am J Surg 153(3):285–290

    Article  CAS  PubMed  Google Scholar 

  38. Bell C, Asolati M, Hamilton E, Fleming J, Nwariaku F, Sarosi G, Anthony T (2005) A comparison of complications associated with colostomy reversal versus ileostomy reversal. Am J Surg 190(5):717–720

    Article  PubMed  Google Scholar 

  39. Keck JO, Collopy BT, Ryan PJ, Fink R, Mackay JR, Woods R (1994) Reversal of Hartmann's procedure—effect of timing and technique on ease and safety. Dis Colon Rectum 37(3):243–248

    Article  CAS  PubMed  Google Scholar 

  40. Vermeulen J, Gosselink MP, Busschbach JJV, Lange JF (2010) Avoiding or reversing Hartmann's procedure provides improved quality of life after perforated diverticulitis. J Gastrointest Surg 14(4):651–657

    Article  PubMed  Google Scholar 

  41. Vermeulen J, Akkersdijk GP, Gosselink MP, Hop WCJ, Mannaerts GH, van der Harst E, Coene PPLO, Weidema WF, Lange JF (2007) Outcome after emergency surgery for acute perforated diverticulitis in 200 cases. Dig Surg 24(5):361–366

    Article  PubMed  Google Scholar 

  42. Schilling MK, Maurer CA, Kollmar O, Buchler MW (2001) Primary vs. secondary anastomosis after sigmoid colon resection for perforated diverticulitis (Hinchey stage III and IV)—a prospective outcome and cost analysis. Dis Colon Rectum 44(5):699–703

    Article  CAS  PubMed  Google Scholar 

  43. Saccomani GE, Santi F, Gramegna A (1993) Primary resection with and without anastomosis for perforation of acute diverticulitis. Acta Chirurgica Belgica 4:169–172

    Google Scholar 

  44. Constantinides VA, Tekkis PP, Athanasiou T, Aziz O, Purkayastha S, Remzi FH, Fazio VW, Aydin N, Darzi A, Senapati A (2006) Primary resection with anastomosis vs. Hartmann's procedure in nonelective surgery for acute colonic diverticulitis: a systematic review. Dis Colon Rectum 49(7):966–981

    Article  PubMed  Google Scholar 

  45. Zorcolo L, Covotta L, Carlomagno N, Bartolo DC (2003) Safety of primary anastomosis in emergency colo-rectal surgery. Color Dis 5(3):262–269

    Article  CAS  Google Scholar 

  46. Sarin S, Boulos PB (1991) Evaluation of current surgical management of acute inflammatory diverticular disease. Ann R Coll Surg Engl 73(5):278–282

    CAS  PubMed  Google Scholar 

  47. Zingg U, Pasternak I, Dietrich M, Seifert B, Oertli D, Metzger U (2010) Primary anastomosis vs Hartmann's procedure in patients undergoing emergency left colectomy for perforated diverticulitis. Color Dis 12(1):54–60

    Article  CAS  Google Scholar 

  48. Gastinger I, Marusch F, Steinert R, Wolff S, Koeckerling F, Lippert H (2005) Protective defunctioning stoma in low anterior resection for rectal carcinoma. Br J Surg 92(9):1137–1142

    Article  CAS  PubMed  Google Scholar 

  49. Mueller MH, Karpitschka M, Renz B, Kleespies A, Kasparek MS, Jauch KW, Kreis ME (2011) Co-morbidity and postsurgical outcome in patients with perforated sigmoid diverticulitis. Int J Color Dis 26(2):227–234

    Article  Google Scholar 

  50. Klink CD, Lioupis K, Binnebosel M, Kaemmer D, Kozubek I, Grommes J, Neumann UP, Jansen M, Willis S (2011) Diversion stoma after colorectal surgery: loop colostomy or ileostomy? Int J Color Dis 26(4):431–436

    Article  Google Scholar 

  51. Sakai Y, Nelson H, Larson D, Maidl L, Young-Fadok T, Ilstrup D (2001) Temporary transverse colostomy vs loop ileostomy in diversion—a case-matched study. Arch Surg 136:(3)338–342

    Article  CAS  PubMed  Google Scholar 

  52. Baker ML, Williams RN, Nightingale JMD (2011) Causes and management of a high-output stoma. Color Dis 13(2):191–197

    Article  CAS  Google Scholar 

  53. Alanis A, Papanicolaou GK, Tadros RR, Fielding LP (1989) Primary resection and anastomosis for treatment of acute diverticulitis. Dis Colon Rectum 32(11):933–939

    Article  CAS  PubMed  Google Scholar 

  54. Blair NP, Germann E (2002) Surgical management of acute sigmoid diverticulitis. Am J Surg 183(5):525–528

    Article  CAS  PubMed  Google Scholar 

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Correspondence to P. H. Alizai.

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PH Alizai and M Schulze-Hagen contributed equally and are both first authors.

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Alizai, P.H., Schulze-Hagen, M., Klink, C.D. et al. Primary anastomosis with a defunctioning stoma versus Hartmann's procedure for perforated diverticulitis—a comparison of stoma reversal rates. Int J Colorectal Dis 28, 1681–1688 (2013). https://doi.org/10.1007/s00384-013-1753-2

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