Skip to main content

Advertisement

Log in

Evaluation of selective defunctioning stoma after low anterior resection for rectal cancer

  • Original Article
  • Published:
International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

Background

Anastomotic leakage is a major concern after resection for low rectal cancer. Therefore, the use of a defunctioning stoma (DS) has been suggested, but limited data exist to clearly determine the necessity of a routine diversion. In our department, the indication of DS was evaluated subjectively by the operating surgeon. The aim of this study was to evaluate the selective use of fecal diversion.

Materials and methods

Retrospective chart review of patients who underwent low anterior resection for carcinoma was performed. The incidence and consequences of clinical leaks were determined in these patients who were considered in two groups: defunctioning stoma and no defunctioning stoma.

Results

From 1995 to 2005, 132 consecutive patients underwent low anterior resection; a DS was performed in 42 patients (31.8%). Median level of anastomosis was 4 cm in both groups. Overall clinical leakage rate was 9.8%: 7.1% (n = 3) with a DS and 11% (n = 10) without a stoma. Mortality rate was 1.5% (n = 2), both in the unprotected group. No patient in the diversion group required a permanent stoma, contrasting with four unprotected patients in which continuity could not be restored after break down of the anastomosis.

Conclusion

Finding lower clinical leakage rate in a probable higher risk group and better outcome when a leak occurs in our study constituted strong evidence of the effectiveness of a DS. Selective use of a DS based on subjective assessment at the time of surgery could not allow experienced surgeons to perform single-stage procedure safely. Construction of a DS seems useful for patients with distal rectal cancer.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Karanjia ND, Corder AP, Holdsworth PJ, Heald RJ (1991) Risk of peritonitis and fatal septicaemia and the need to defunction the low anastomosis. Br J Surg 78:196–198

    Article  PubMed  CAS  Google Scholar 

  2. Heald RJ, Ryall RD (1986) Recurrence and survival after total mesorectal excision for rectal cancer. Lancet 1:1479–1482

    Article  PubMed  CAS  Google Scholar 

  3. Heald RJ, Husband EM, Ryall RD (1982) The mesorectum in rectal cancer surgery–the clue to pelvic recurrence. Br J Surg 69:613–616

    Article  PubMed  CAS  Google Scholar 

  4. Parc R, Tiret E, Frileux P, Moszkowski E, Loygue J (1986) Resection and colo-anal anastomosis with colonic reservoir for rectal carcinoma. Br J Surg 73:139–141

    Article  PubMed  CAS  Google Scholar 

  5. Lazorthes F, Fages P, Chiotasso P, Bugat R (1986) Synchronous abdominotrans-sphincteric resection of low rectal cancer: new technique for direct colo-anal anastomosis. Br J Surg 73:573–575

    Article  PubMed  CAS  Google Scholar 

  6. Rullier E, Laurent C, Bretagnol F, Rullier A, Vendrely V, Zerbib F (2005) Sphincter-saving resection for all rectal carcinomas: the end of the 2 cm distal rule. Ann Surg 241:465–469

    Article  PubMed  Google Scholar 

  7. Arbman G, Nilsson E, Hallbook O, Sjodahl R (1996) Local recurrence following total mesorectal excision for rectal cancer. Br J Surg 83:375–379

    Article  PubMed  CAS  Google Scholar 

  8. Karanjia ND, Corder AP, Bearn P, Heald RJ (1994) Leakage from stapled low anastomosis after total mesorectal excision for carcinoma of the rectum. Br J Surg 81:1224–1226

    Article  PubMed  CAS  Google Scholar 

  9. Hilsabeck JR (1982) The presacral space as a collector of fluid accumulations following rectal anastomosis: tolerance of rectal anastomosis to closed suction pelvic drainage. Dis Colon Rectum 25:680–684

    Article  PubMed  CAS  Google Scholar 

  10. Merad F, Hay JM, Fingerhut A, Yahchouchi E, Laborde Y, Pelissier E, Msika S, Flamant Y (1999) Is prophylactic pelvic drainage useful after elective rectal or anal anastomosis? A multicenter controlled randomized trial. French Association for Surgical Research. Surgery 125:529–535

    PubMed  CAS  Google Scholar 

  11. Fingerhut A, Msika S, Yahchouchi E, Merad F, Hay JM, Millat B (2000) Neither pelvic nor abdominal drainage is needed after anastomosis in elective, uncomplicated, colorectal surgery. Ann Surg 231:613–614

    Article  PubMed  CAS  Google Scholar 

  12. Johnson CD, Lamont PM, Orr N, Lennox M (1989) Is a drain necessary after colonic anastomosis. J R Soc Med 82:661–664

    PubMed  CAS  Google Scholar 

  13. Sagar PM, Couse N, Kerin M, May J, MacFie J (1993) Randomized trial of drainage of colorectal anastomosis. Br J Surg 80:769–771

    Article  PubMed  CAS  Google Scholar 

  14. McArdle CS, Hole D (1991) Impact of variability among surgeons on postoperative morbidity and mortality and ultimate survival. BMJ 302:1501–1505

    PubMed  CAS  Google Scholar 

  15. Kessler H, Hermanek P, Wiebelt H (1993) Operative mortality in carcinoma of the rectum. Results of the German Multicentre Study. Int J Colorectal Dis 8:158–166

    Article  PubMed  CAS  Google Scholar 

  16. Fielding LP, Stewart-Brown S, Blesovsky L, Kearney G (1980) Anastomotic integrity after operations for large-bowel cancer: a multicentre study. BMJ 281:411–414

    Article  PubMed  CAS  Google Scholar 

  17. Hannan EL, O'Donnell JF, Kilburn H, Bernard HR, Yazici A (1989) Investigation of the relationship between volume and mortality for surgical procedures performed in New York State hospitals. JAMA 262:503–510

    Article  PubMed  CAS  Google Scholar 

  18. Rullier E, Laurent C, Garrelon JL, Michel P, Saric J, Parneix M (1998) Risk factors for anastomotic leakage after resection of rectal cancer. Br J Surg 85:355–358

    Article  PubMed  CAS  Google Scholar 

  19. Sorensen LT, Jorgensen T, Kirkeby LT, Skovdal J, Vennits B, Wille-Jorgensen P (1999) Smoking and alcohol abuse are major risk factors for anastomotic leakage in colorectal surgery. Br J Surg 86:927–931

    Article  PubMed  CAS  Google Scholar 

  20. Testini M, Margani M, Amuruso M, Lirridini G, Bonamo GM (2000) The dehiscence of colorectal anastomoses: the risk factors. Ann Ital Chir 71:433–440

    PubMed  CAS  Google Scholar 

  21. Parc Y, Frileux P, Schmitt G, Dehni N, Ollivier JM, Parc R (2000) Management of postoperative peritonitis after anterior resection: experience from a referral intensive care unit. Dis Colon Rectum 43:579–587

    Article  PubMed  CAS  Google Scholar 

  22. Hallbook O, Sjodahl R (1996) Anastomotic leakage and functional outcome after anterior resection of the rectum. Br J Surg 83:60–62

    Article  PubMed  CAS  Google Scholar 

  23. Bell SW, Walker KG, Rickard MJ, Sinclair G, Dent OF, Chapuis PH, Bokey EL (2003) Anastomotic leakage after curative anterior resection results in a higher prevalence of local recurrence. Br J Surg 90:1261–1266

    Article  PubMed  CAS  Google Scholar 

  24. Tornqvist A, Blomquist P, Jiborn H, Zederfeldt B (1990) The effect of diverting colostomy on anastomotic healing after resection of left colon obstruction. An experimental study in the rat. Int J Colorectal Dis 5:167–169

    Article  PubMed  CAS  Google Scholar 

  25. Mansson P, Fork T, Blomqvist P, Jeppsson B, Thorlacius H (2000) Diverting colostomy increases anastomotic leakage in the rat colon. Eur Surg Res 32:246–250

    Article  PubMed  CAS  Google Scholar 

  26. Bielecki K, Grotowski M, Kalczak M (1995) Influence of proximal end diverting colostomy on the healing of left-sided colonic anastomosis: an experimental study in rats. Int J Colorectal Dis 10:193–196

    Article  PubMed  CAS  Google Scholar 

  27. Pakkastie TE, Ovaska JT, Pekkala ES, Luukkonen PE, Jarvinen HJ (1997) A randomized study of colostomies in low colorectal anastomoses. Eur J Surg 163:929–933

    PubMed  CAS  Google Scholar 

  28. Dehni N, Schlegel RD, Cunningham C, Guiguet M, Tiret E, Parc R (1998) Influence of a defunctioning stoma on leakage rates after low colorectal anastomosis and colonic J pouch-anal anastomosis. Br J Surg 85:1114–1117

    Article  PubMed  CAS  Google Scholar 

  29. Antonsen HK, Kronborg O (1987) Early complications after low anterior resection for rectal cancer using the EEA stapling device. A prospective trial. Dis Colon Rectum 30:579–583

    Article  PubMed  CAS  Google Scholar 

  30. Pakkastie TE, Luukkonen PE, Jarvinen HJ (1994) Anastomotic leakage after anterior resection of the rectum. Eur J Surg 160:293–297

    PubMed  CAS  Google Scholar 

  31. Graffner H, Fredlund P, Olsson SA, Oscarson J, Petersson BG (1983) Protective colostomy in low anterior resection of the rectum using the EEA stapling instrument. A randomized study. Dis Colon Rectum 26:87–90

    Article  PubMed  CAS  Google Scholar 

  32. Grabham JA, Moran BJ, Lane RH (1995) Defunctioning colostomy for low anterior resection: a selective approach. Br J Surg 82:1331–1332

    Article  PubMed  CAS  Google Scholar 

  33. Cavaliere F, Pemberton JH, Cosimelli M, Fazio VW, Beart RW (1995) Coloanal anastomosis for rectal cancer. Long-term results at the Mayo and Cleveland Clinics. Dis Colon Rectum 38:807–812

    Article  PubMed  CAS  Google Scholar 

  34. Kim NK, Lim DJ, Yun SH, Sohn SK, Min JS (2001) Ultralow anterior resection and coloanal anastomosis for distal rectal cancer: functional and oncological results. Int J colorectal Dis 16:234–237

    Article  PubMed  CAS  Google Scholar 

  35. Fielding LP, Stewart-Brown S, Hittinger R, Blesovsky L (1984) Covering stoma for elective anterior resection of the rectum: an outmoded operation. Am J Surg 147:524–530

    Article  PubMed  CAS  Google Scholar 

  36. Mealy K, Burke P, Hyland J (1992) Anterior resection without a defunctioning colostomy: questions of safety. Br J Surg 79:305–307

    Article  PubMed  CAS  Google Scholar 

  37. Peeters KC, Tollenaar RA, Marijnen CA, Klein Kranenbarg E, Steup WH, Wiggers T, Rutten HJ, van de Velde CJ (2005) Risk factors for anastomotic failure after total mesorectal excision of rectal cancer. Br J Surg 92:211–216

    Article  PubMed  CAS  Google Scholar 

  38. Wittmann DH, Schein M, Condon RE (1996) Management of secondary peritonitis. Ann Surg 224:10–18

    Article  PubMed  CAS  Google Scholar 

  39. Frileux P, Quilichini MA, Cugnenc PH, Parc R, Levy E, Loygue J (1985) Postoperative peritonitis of colonic origin. Apropos of 155 cases. Ann Chir 39:649–659

    PubMed  CAS  Google Scholar 

  40. Schrock TR, Deveney CW, Dunphy JE (1973) Factor contributing to leakage of colonic anastomoses. Ann Surg 177:513–518

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to F. Michot.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lefebure, B., Tuech, J.J., Bridoux, V. et al. Evaluation of selective defunctioning stoma after low anterior resection for rectal cancer. Int J Colorectal Dis 23, 283–288 (2008). https://doi.org/10.1007/s00384-007-0380-1

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00384-007-0380-1

Keywords

Navigation