Abstract
Ulcerative colitis (UC) affects women of all ages, with a peak incidence in the third and fourth decades, at the prime of their reproductive years [Baiocco PJ, Korelitz BI (1984) The influence of inflammatory bowel disease and its treatment on pregnancy and fetal outcome. J Clin Gastroenterol 6(3):211–216]. We describe a case of fulminating UC at 28 weeks' gestation treated by combined emergency subtotal colectomy and caesarean section with excellent foetal and maternal outcome. A treatment algorithm is suggested, and the literature surrounding inflammatory bowel disease in pregnancy is reviewed.
References
Baiocco PJ, Korelitz BI (1984) The influence of inflammatory bowel disease and its treatment on pregnancy and fetal outcome. J Clin Gastroenterol 6(3):211–216
Miller JP (1986) Inflammatory bowel disease in pregnancy: a review. J R Soc Med 79(4):221–225
Castiglione F, Pignata S, Morace F, Sarubbi A, Baratta MA, D'Agostino L, D'Arienzo A, Mazzacca G (1996) Effect of pregnancy on the clinical course of a cohort of women with inflammatory bowel disease. Ital J Gastroenterol 28(4):199–204
Mogadam M, Dobbins WO III, Korelitz BI, Ahmed SW (1981) Pregnancy in inflammatory bowel disease: effect of sulfasalazine and corticosteroids on fetal outcome. Gastroenterology 80(1):72–76
Korelitz BI (1998) Inflammatory bowel disease and pregnancy. Gastroenterol Clin North Am 27(1):213–224
Levine MG, Esser D (1988) Total parenteral nutrition for the treatment of severe hyperemesis gravidarum: maternal nutritional effects and fetal outcome. Obstet Gynecol 72(1):102–107
Ishijima N, Ojima E, Tonouchi H, Suzuki H, Fukunishi S (1999) Delivery of a normal newborn after intensive medical treatment for an acute exacerbation of ulcerative colitis during pregnancy: a case report. Surg Today 29(12):1257–1259
Banks BM, Korelitz BI, Zetzel L (1957) The course of non-specific ulcerative colitis: review of twenty years' experience and late results. Gastroenterology 32(6):983–1012
Hannan IM, Kirsner JB (1985) Inflammatory bowel disease in pregnant woman. Clin Perinatol 12:682–699
Webb MJ, Sedlack RE (1974) Ulcerative colitis in pregnancy. Med Clin North Am 58(4):823–882
DeVore GR (1980) Acute abdominal pain in the pregnant patient due to pancreatitis, acute appendicitis, cholecystitis or peptic ulcer disease. Clin Perinatol 7(2):349–369
Donaldson RM (1985) Management of medical problems in pregnancy in inflammatory bowel disease. N Engl J Med 312(25):1616–1619
Subhabi JM, Hamilton MI (1998) Review article: the management of inflammatory bowel disease during pregnancy. Aliment Pharmacol Ther 12(11):1039–1053
Cappell MS, Colon VJ, Sidhom OA (1996) A study at ten medical centres of the safety and efficacy of 48 sigmoidoscopies and 8 colonoscopies during pregnancy with follow up of fetal outcome and with comparison to control groups. Dig Dis Sci 141(12):2353–2361
Greenfield C, Pounder RE, Craft IL, Lewis AA (1983) Severe ulcerative colitis during successful pregnancy. Postgrad Med J 59(693):459–462
Boulton R, Hamilton M, Lewis A, Walker P, Pounder R (1994) Fulminant ulcerative colitis in pregnancy. Am J Gastroenterol 89(6):931–933
Shoenut JP, Semelka RC, Silverman R, Yaffe CS, Mickflikner AB (1993) Magnetic resonance imaging in inflammatory bowel disease. J Clin Gastroenterol 17(3):244–247
van Loon AJ, Mantingh A, Serlier EK, Kroon G, Mooyaart EL, Huisjes HJ (1997) Randomised controlled trial of magnetic-resonance pelvimetry in breech presentation at term. Lancet 350(9094):1799–1804
Watson WJ, Gaines TE (1987) Third-trimester colectomy for severe ulcerative colitis a case report. J Reprod Med 32(11):869–872
Georgy FM (1974) Fulminating ulcerative colitis in pregnancy. Obstet Gynecol 44(4):603–606
Anderson JB, Turner GM, Williamson RC (1987) Fulminant ulcerative colitis in late pregnancy and the puerperium. J R Soc Med 80(8):492–494
Kelley MJ, Hunt TM, Wicks AC, Mayne CJ (1994) Fulminant ulcerative colitis and parturition: a need to alter current management? Br J Obstet Gynaecol 101(2):166–167
Kammerer WS (1979) Non-obstetric surgery during pregnancy. Med Clin North Am 63(6):1157–1164
Ooi BS, Remzi FH, Fazio VW (2003) Turnbull–blowhole colostomy for toxic ulcerative colitis in pregnancy: report of two cases. Dis Colon Rectum 46(1):111–115
Cooksey G, Gunn A, Wotherspoon WC (1985) Surgery for acute ulcerative colitis and toxic megacolon during pregnancy. Br J Surg 72(7):547
McEwan H (1972) Ulcerative colitis in pregnancy. Proc Roy Soc Med 65:279–281
Flatmark AL, Nordoy A, Gjone E (1971) Radical surgery for ulcerative colitis during pregnancy. Scand J Gastroenterol 6(1):45–47
Bohe MG, Ekelund GR, Genell SN, Gennser GM, Jiborn HA, Leandoer LJ, Lindstrom CG, Svanberg LK (1983) Surgery for fulminating colitis during pregnancy. Dis Colon Rectum 26(2):119–122
Acknowledgements
Asif Patel, Colo-proctology coordinator, Royal London Hospital, is gratefully acknowledged.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Haq, A.I., Sahai, A., Hallwoth, S. et al. Synchronous colectomy and caesarean section for fulminant ulcerative colitis: case report and review of the literature. Int J Colorectal Dis 21, 465–469 (2006). https://doi.org/10.1007/s00384-005-0027-z
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00384-005-0027-z