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Pediatric microcystic meningioma: a clinical, histological, and radiographic case-based review

  • Case-Based Update
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Abstract

Background

Microcystic meningioma (MM) is a World Health Organization grade I tumor that is rare in the pediatric population. Meningiomas account for approximately 2–4 % of all childhood central nervous system (CNS) tumors compared to approximately 20 % of all adult CNS tumors. The authors present one of the few confirmed cases of microcystic meningioma in a child and discuss the characteristic radiographic appearance and histological findings.

History

We report the case of an 11-year-old boy who presented with first-time seizure and imaging consistent with brain tumor. There was significant vasogenic edema within the entire right hemisphere, disproportionate to the size of the falcine-based tumor. Histopathological analysis revealed the microcystic subtype of meningioma.

Discussion

We review the radiographic characteristics, histopathological findings, and reported pediatric cases of MM in conjunction with our case.

Conclusion

MM has distinct radiographic characteristics (variable enhancement, lack of a dural tail, and disproportionate vasogenic edema) that can be misinterpreted in the pediatric population, suggesting a more aggressive tumor.

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Conflict of interest

The authors report no conflict of interest concerning the materials and methods used in this study or the findings specified in this paper.

Author information

Authors and Affiliations

  1. Department of Neurosurgery and Brain Repair, Morsani School of Medicine, University of South Florida, Tampa, FL, USA

    Jotham Manwaring, Amir Ahmadian, Luis Rodriguez, Carolyn Carey & Gerald F. Tuite

  2. Neuroscience Institute, All Children’s Hospital/Johns Hopkins Medicine, 601 5th Street South, Suite 511, St. Petersburg, FL, 33701, USA

    Luis Rodriguez, Carolyn Carey & Gerald F. Tuite

  3. Department of Pediatric Hematology/Oncology, All Children’s Hospital/Johns Hopkins Medicine, St. Petersburg, FL, USA

    Stacie Stapleton

  4. Department of Pathology, All Children’s Hospital/Johns Hopkins Medicine, St. Petersburg, FL, USA

    Ignacio Gonzalez-Gomez

Authors
  1. Jotham Manwaring
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  2. Amir Ahmadian
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  3. Stacie Stapleton
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  4. Ignacio Gonzalez-Gomez
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  5. Luis Rodriguez
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  6. Carolyn Carey
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  7. Gerald F. Tuite
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Corresponding author

Correspondence to Gerald F. Tuite.

Additional information

Previous Publication: This patient’s case was presented as a poster at the 15th International Symposium on Pediatric Neuro-Oncology on June 12, 2012 in Toronto, Canada. We have added detailed radiographic and histological components as well as a review of the literature. It has never been published.

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Manwaring, J., Ahmadian, A., Stapleton, S. et al. Pediatric microcystic meningioma: a clinical, histological, and radiographic case-based review. Childs Nerv Syst 29, 361–365 (2013). https://doi.org/10.1007/s00381-012-1991-6

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  • DOI: https://doi.org/10.1007/s00381-012-1991-6

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