Skip to main content

Advertisement

Log in

Update on Greenlight laser vaporization (PVP) 2014

  • Invited Review
  • Published:
World Journal of Urology Aims and scope Submit manuscript

Abstract

Purpose

To asses the (1) outcomes and (2) intraoperative, perioperative, and long-term complications of photoselective vaporization of the prostate (PVP) with Greenlight laser.

Methods

A systematic review of outcomes and complications of PVP was conducted. The article selection process was performed according to PRISMA guidelines and included publications published between 2009 and 2014.

Results

All generations of PVP (80, 120, 180 W) lead to a significant improvement of micturition symptoms (IPSS, QoL) and voiding parameters (Q max, PVR volume) during follow-up. Data on sexual function are heterogeneous and suggest a trend toward decline in erectile function in men with sustained preoperative erection. The rate of intraoperative complications is low. Data on peri- and postoperative complications show a large variation that mainly can be attributed to heterogeneity in documentation.

Conclusions

PVP leads to a statistically significant and clinically relevant improvement of voiding parameters and micturition symptoms in patients with prostates <100 ml. The technique is characterized by a high degree of intra- and perioperative safety. Long-term evidence on functional outcomes and complications beyond 3 years from RCTs is currently missing for all generations of the Greenlight laser.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Oelke M, Bachmann A, Descazeaud A, Emberton M, Gravas S, Michel MC, N’Dow J, Nordling J, de la Rosette JJ (2013) EAU guidelines on the treatment and follow-up of non-neurogenic male lower urinary tract symptoms including Benign prostatic obstruction. Eur Urol 64(1):118–140

    Article  PubMed  Google Scholar 

  2. Cornu JN, Ahyai S, Bachmann A, de la Rosette J, Gilling P, Gratzke C, McVary K, Novara G, Woo H, Madersbacher S (2014) A systematic review and meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from Benign prostatic obstruction: an update. Eur Urol. doi:10.1016/j.eururo.2014.06.017

  3. Rieken M, Bachmann A (2014) Laser treatment of benign prostate enlargement—which laser for which prostate? Nat Rev Urol 11(3):142–152

    Article  PubMed  Google Scholar 

  4. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, McQuay HJ (1996) Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 17(1):1–12

    Article  CAS  PubMed  Google Scholar 

  5. Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213

    Article  PubMed Central  PubMed  Google Scholar 

  6. Bouchier-Hayes DM, Van Appledorn S, Bugeja P, Crowe H, Challacombe B, Costello AJ (2010) A randomized trial of photoselective vaporization of the prostate using the 80 W potassium-titanyl-phosphate laser vs transurethral prostatectomy, with a 1-year follow-up. BJU Int 105(7):964–969

    Article  PubMed  Google Scholar 

  7. Mohanty NK, Vasudeva P, Kumar A, Prakash S, Jain M, Arora RP (2012) Photoselective vaporization of prostate vs. transurethral resection of prostate: a prospective, randomized study with one year follow-up. IJU 28(3):307–312

    PubMed Central  PubMed  Google Scholar 

  8. Elshal AM, Elmansy HM, Elhilali MM (2013) Two laser ablation techniques for a prostate less than 60 ml: lessons learned 70 months after a randomized controlled trial. Urology 82(2):416–422

  9. Elzayat EA, Al-Mandil MS, Khalaf I, Elhilali MM (2009) Holmium laser ablation of the prostate versus photoselective vaporization of prostate 60 cc or less: short-term results of a prospective randomized trial. J Urol 182(1):133–138

    Article  PubMed  Google Scholar 

  10. Hai MA (2009) Photoselective vaporization of prostate: five-year outcomes of entire clinic patient population. Urology 73(4):807–810

    Article  PubMed  Google Scholar 

  11. Malde S, Rajagopalan A, Patel N, Simoes A, Choi W, Shrotri N (2012) Potassium-titanyl-phosphate laser photoselective vaporization for benign prostatic hyperplasia: 5-year follow-up from a district general hospital. J Endourol 26(7):878–883

    Article  PubMed  Google Scholar 

  12. Kim HS, Cho MC, Ku JH, Kim SW, Paick JS (2010) The efficacy and safety of photoselective vaporization of the prostate with a potassium-titanyl-phosphate laser for symptomatic benign prostatic hyperplasia according to prostate size: 2-year surgical outcomes. Korean J Urol 51(5):330–336

    Article  PubMed Central  PubMed  Google Scholar 

  13. Kumar A, Vasudeva P, Kumar N, Nanda B, Mohanty NK (2012) Evaluation of the effect of photoselective vaporization of the prostate on sexual function in a prospective study: a single center experience of 150 patients. J Endourol [Epub ahead of print]

  14. Bruyere F, Puichaud A, Pereira H, Faivre d’Arcier B, Rouanet A, Floc’h AP, Bodin T, Brichart N (2010) Influence of photoselective vaporization of the prostate on sexual function: results of a prospective analysis of 149 patients with long-term follow-up. Eur Urol 58(2):207–211

    Article  PubMed  Google Scholar 

  15. Al-Ansari A, Younes N, Sampige VP, Al-Rumaihi K, Ghafouri A, Gul T, Shokeir AA (2010) GreenLight HPS 120 W laser vaporization versus transurethral resection of the prostate for treatment of benign prostatic hyperplasia: a randomized clinical trial with midterm follow-up. Eur Urol 58(3):349–355

    Article  PubMed  Google Scholar 

  16. Capitan C, Blazquez C, Martin MD, Hernandez V, de la Pena E, Llorente C (2011) GreenLight HPS 120 W laser vaporization versus transurethral resection of the prostate for the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia: a randomized clinical trial with 2-year follow-up. Eur Urol 60(4):734–739

    Article  PubMed  Google Scholar 

  17. Pereira-Correia JA, de Moraes Sousa KD, Santos JB, de Morais Perpetuo D, Lopes-da-Silva LF, Krambeck RL, Muller VJ, Vaz FP (2012) GreenLight HPS 120 W laser vaporization vs transurethral resection of the prostate (<60 mL): a 2-year randomized double-blind prospective urodynamic investigation. BJU Int 110(8):1184–1189

    Article  PubMed  Google Scholar 

  18. Lukacs B, Loeffler J, Bruyere F, Blanchet P, Gelet A, Coloby P, De la Taille A, Lemaire P, Baron JC, Cornu JN, Aout M, Rousseau H, Vicaut E, Group RS (2012) Photoselective vaporization of the prostate with GreenLight 120 W laser compared with monopolar transurethral resection of the prostate: a multicenter randomized controlled trial. Eur Urol 61(6):1165–1173

    Article  PubMed  Google Scholar 

  19. Kumar A, Vasudeva P, Kumar N, Nanda B, Jha SK, Mohanty NK (2013) A prospective randomized comparative study of monopolar transurethral resection of prostate (TURP), bipolar TURP and photoselective vaporization of prostate in patients presenting with benign prostatic obstruction—a single center experience. J Endourol 27(10):1245–1253

  20. Gu X, Vricella GJ, Spaliviero M, Wong C (2012) Does size really matter? The impact of prostate volume on the efficacy and safety of GreenLight HPS laser photoselective vaporization of the prostate. J Endourol 26(5):525–530

    Article  PubMed  Google Scholar 

  21. Bachmann A, Tubaro A, Barber N, d’Ancona F, Muir G, Witzsch U, Grimm MO, Benejam J, Stolzenburg JU, Riddick A, Pahernik S, Roelink H, Ameye F, Saussine C, Bruyere F, Loidl W, Larner T, Gogoi NK, Hindley R, Muschter R, Thorpe A, Shrotri N, Graham S, Hamann M, Miller K, Schostak M, Capitan C, Knispel H, Thomas JA (2014) 180 W XPS GreenLight laser vaporisation versus transurethral resection of the prostate for the treatment of benign prostatic obstruction: 6-month safety and efficacy results of a European multicentre randomised trial—the GOLIATH study. Eur Urol 65(5):931–942

    Article  PubMed  Google Scholar 

  22. Bachmann A, Muir GH, Collins EJ, Choi BB, Tabatabaei S, Reich OM, Gomez-Sancha F, Woo HH (2012) 180 W XPS GreenLight laser therapy for benign prostate hyperplasia: early safety, efficacy, and perioperative outcome after 201 procedures. Eur Urol 61(3):600–607

    Article  PubMed  Google Scholar 

  23. Campbell NA, Chung AS, Yoon PD, Thangasamy I, Woo HH (2013) Early experience photoselective vaporisation of the prostate using the 180 W lithium triborate and comparison with the 120 W lithium triborate laser. Prostate Int 1(1):42–45

    Article  PubMed Central  PubMed  Google Scholar 

  24. Chung AS, Chabert C, Yap HW, Lam J, Awad N, Nuwayhid F, Redwig F, Rashid P, Woo HH (2012) Photoselective vaporization of the prostate using the 180 W lithium triborate laser. ANZ J Surg 82(5):334–337

    Article  PubMed  Google Scholar 

  25. Hueber PA, Liberman D, Ben-Zvi T, Woo H, Hai MA, Te AE, Chughtai B, Lee R, Rutman M, Gonzalez RR, Barber N, Al-Hathal N, Al-Qaoud T, Trinh QD, Zorn KC (2013) 180 W vs 120 W lithium triborate photoselective vaporization of the prostate for benign prostatic hyperplasia: a global, multicenter comparative analysis of perioperative treatment parameters. Urology 82(5):1108–1113

    Article  PubMed  Google Scholar 

  26. Tasci AI, Ilbey YO, Luleci H, Cicekler O, Sahin S, Cevik C, Tugcu V (2011) 120 W GreenLight laser photoselective vaporization of prostate for benign prostatic hyperplasia: midterm outcomes. Urology 78(1):134–140

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

M. Rieken: No conflict of interest. A. Bachmann: Principal investigator of the GOLIATH study, which was sponsored by American Medical Systems (AMS), is advisor for AMS, and receives honoraria for presentations.

Ethical standard

All human studies have been approved by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Malte Rieken.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rieken, M., Bachmann, A. Update on Greenlight laser vaporization (PVP) 2014. World J Urol 33, 531–537 (2015). https://doi.org/10.1007/s00345-014-1437-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00345-014-1437-8

Keywords

Navigation