Abstract
Purpose
To asses the (1) outcomes and (2) intraoperative, perioperative, and long-term complications of photoselective vaporization of the prostate (PVP) with Greenlight laser.
Methods
A systematic review of outcomes and complications of PVP was conducted. The article selection process was performed according to PRISMA guidelines and included publications published between 2009 and 2014.
Results
All generations of PVP (80, 120, 180 W) lead to a significant improvement of micturition symptoms (IPSS, QoL) and voiding parameters (Q max, PVR volume) during follow-up. Data on sexual function are heterogeneous and suggest a trend toward decline in erectile function in men with sustained preoperative erection. The rate of intraoperative complications is low. Data on peri- and postoperative complications show a large variation that mainly can be attributed to heterogeneity in documentation.
Conclusions
PVP leads to a statistically significant and clinically relevant improvement of voiding parameters and micturition symptoms in patients with prostates <100 ml. The technique is characterized by a high degree of intra- and perioperative safety. Long-term evidence on functional outcomes and complications beyond 3 years from RCTs is currently missing for all generations of the Greenlight laser.
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Conflict of interest
M. Rieken: No conflict of interest. A. Bachmann: Principal investigator of the GOLIATH study, which was sponsored by American Medical Systems (AMS), is advisor for AMS, and receives honoraria for presentations.
Ethical standard
All human studies have been approved by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.
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Rieken, M., Bachmann, A. Update on Greenlight laser vaporization (PVP) 2014. World J Urol 33, 531–537 (2015). https://doi.org/10.1007/s00345-014-1437-8
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DOI: https://doi.org/10.1007/s00345-014-1437-8