Abstract
Purpose
This study aimed to identify predictors of European men who self-reported being diagnosed with benign prostatic hyperplasia (DxBPH) compared to men with moderate-to-severe lower urinary tract symptoms [American Urological Association Symptom Index (AUA-SI) score ≥8] who did not self-report a BPH diagnosis (non-DxBPH).
Methods
Data were taken from the 2010 European National Health and Wellness Survey; a cross-sectional, self-administered, Internet-based questionnaire. This analysis included males ≥40 years with DxBPH or without DxBPH, but with AUA-SI ≥8. Chi-square tests were used for categorical variables and independent samples t tests were used for continuous variables. Logistic regressions were conducted among all men ≥40 years to predict being DxBPH.
Results
About 1,638 DxBPH and 3,676 non-DxBPH men were included. The estimated prevalence of DxBPH and non-DxBPH was 8.53 and 19.13 %. Men with DxBPH were older than non-DxBPH males (mean age 66.1 and 58.3, P < 0.001). The mean AUA-SI score was 11.3 for DxBPH and 13.2 for non-DxBPH. Being older (OR = 1.077), having a university education (OR = 1.252), having private health insurance (OR = 1.186), and specific health behaviors/attitudes [regular exercise (OR = 1.191), visiting a doctor within the previous 6 months (OR = 2.398), consulting with a medical professional when not feeling well (OR = 1.097), reporting having an attentive doctor (OR = 1.112)], and higher voiding symptoms (OR = 1.032) were significant predictors of DxBPH.
Conclusions
Older men with higher education and access to care and more engagement in their healthcare were more likely to self-report being diagnosed.
Similar content being viewed by others
References
American Urological Association, Inc (2010) Management of benign prostatic hyperplasia (BPH). http://www.auanet.org/content/guidelines-and-quality-care/clinical-guidelines.cfm?sub=bph. Accessed 03 Oct 2013
European Association of Urology (2013) Guidelines on the treatment of non-neurogenic male LUTS, including benign prostatic obstruction. http://www.uroweb.org/?id=217&tyid=2. Accessed 03 Oct 2013
Trueman P, Hood SC, Nayak US, Mrazek MF (1999) Prevalence of lower urinary tract symptoms and self-reported diagnosed ‘benign prostatic hyperplasia’, and their effect on quality of life in a community-based survey of men in the UK. BJU Int 83:410–415
Hoesl CE, Woll EM, Burkart M, Altwein JE (2005) Erectile dysfunction (ED) is prevalent, bothersome and underdiagnosed in patients consulting urologists for benign prostatic syndrome (BPS). Eur Urol 47:511–517
Rosen R, Altwein J, Boyle P, Kirby RS, Lukacs B, Meuleman E, O’Leary MP, Puppo P, Robertson C, Giuliano F (2003) Lower urinary tract symptoms and male sexual dysfunction: the multinational survey of the aging male (MSAM-7). Eur Urol 44:637–649
Rosen RC, Wei JT, Althof SE, Seftel AD, Miner M, Perelman MA, BPH Registry and Patient Survey Steering Committee (2009) Association of sexual dysfunction with lower urinary tract symptoms of BPH and BPH medical therapies: results from the BPH Registry. Urology 73:562–566
Rhoden EL, Riedner CE, Fornari A, Fuchs SC, Ribeiro EP (2008) Evaluation of the association between lower urinary tract symptoms and erectile dysfunction, considering its multiple risk factors. J Sex Med 5:2662–2668
Morant S, Bloomfield G, Vats V, Chapple C (2009) Increased sexual dysfunction in men with storage and voiding lower urinary tract symptoms. J Sex Med 6:1103–1110
Gacci M, Eardley I, Giuliano F, Hatzichristou D, Kaplan SA, Maggi M, McVary KT, Mirone V, Porst H, Roehrborn CG (2011) Critical analysis of the relationship between sexual dysfunctions and lower urinary tract symptoms due to benign prostatic hyperplasia. Eur Urol 60:809–825
McVary K, Foley KA, Long SR, Sander S, Curtice TG, Shah H (2008) Identifying patients with benign prostatic hyperplasia through a diagnosis of, or treatment for, erectile dysfunction. Curr Med Res Opin 24:775–784
Seftel AD, de la Rosette J, Birt J, Porter V, Zarotsky V, Viktrup L (2013) Coexisting lower urinary tract symptoms and erectile dysfunction: a systematic review of epidemiological data. Int J Clin Pract 67:32–45
Braun MH, Sommer F, Haupt G, Mathers MJ, Reifenrath B, Engelmann UH (2003) Lower urinary tract symptoms and erectile dysfunction: co-morbidity or typical “Aging Male” symptoms? Results of the “Cologne Male Survey”. Eur Urol 44:588–594
Khoo EM, Tan HM, Low WY (2008) Erectile dysfunction and comorbidities in aging men: an urban cross-sectional study in Malaysia. J Sex Med 5:2925–2934
Li MK, Garcia L, Patron N, Moh LC, Sundram M, Leungwattanakij S, Pripatnanont C, Cheng C, Chi-Wai M, Loi-Cheong N (2008) An Asian multinational prospective observational registry of patients with benign prostatic hyperplasia, with a focus on comorbidities, lower urinary tract symptoms and sexual function. BJU Int 101:197–202
Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, Van Kerrebroeck P, Victor A, Wein A, Standardisation Sub-Committee of the International Continence Society (2003) The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society. Urology 61:37–49
American Urological Association, Inc (2003) Benign prostatic hyperplasia (BPH): a patient’s guide. Benign prostatic hyperplasia guideline update panel of the AUA. http://www.auanet.org/content/clinical-practice-guidelines/clinical-guidelines/archived-guidelines/chapt_1_appendix.pdf. Accessed 22 May 2012
Barry MJ, Fowler FJ Jr, O’Leary MP, Bruskewitz RC, Holtgrewe HL, Mebust WK, Cockett AT (1992) The American Urological Association symptom index for benign prostatic hyperplasia. The Measurement Committee of the American Urological Association. J Urol 148:1549–1557
Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383
Irwin DE, Milsom I, Kopp Z, Abrams P, Artibani W, Herschorn S (2009) Prevalence, severity, and symptom bother of lower urinary tract symptoms among men in the EPIC study: impact of overactive bladder. Eur Urol 56:14–20
Boyle P, Robertson C, Mazzetta C, Keech M, Hobbs FD, Fourcade R, Kiemeney L, Lee C, UrEpik Study Group (2003) The prevalence of lower urinary tract symptoms in men and women in four centres. the UrEpik study. BJU Int 92:409–414
Jacobsen SJ, Jacobson DJ, Girman CJ, Roberts RO, Rhodes T, Guess HA, Lieber MM (1999) Treatment for benign prostatic hyperplasia among community dwelling men: the Olmsted County study of urinary symptoms and health status. J Urol 162:1301–1306
de Boer BJ, Bots ML, Nijeholt AA, Moors JP, Verheij TJ (2005) The prevalence of bother, acceptance, and need for help in men with erectile dysfunction. J Sex Med 2:445–450
Acknowledgments
This study was funded by Eli Lilly and Company. The authors would like to thank Teri Tucker, BA, of inVentiv Health Clinical, for her editorial contributions to this manuscript and Rebecca McCracken, MSPH, also of inVentiv Health Clinical, for her writing contributions to this manuscript.
Conflict of interest
SAF, ES, and LV are employees and stockholders of Eli Lilly and Company. MD is an employee of Kantar Health, which received funding from Eli Lilly and Company to conduct the analysis.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Foster, S.A., Shortridge, E.F., DiBonaventura, M. et al. Predictors of self-reported benign prostatic hyperplasia in European men: analysis of the European National Health and Wellness Survey. World J Urol 33, 639–647 (2015). https://doi.org/10.1007/s00345-014-1366-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00345-014-1366-6