Abstract
Our understanding of the molecular genetic basis of several key performance traits in pigs has been significantly advanced through the quantitative trait loci (QTL) mapping approach. However, in contrast to growth and fatness traits, the genetic basis of feed intake traits has rarely been investigated through QTL mapping. Since feed intake is an important component of efficient pig production, the identification of QTL affecting feed intake may lead to the identification of genetic markers that can be used in selection programs. In this study a QTL analysis for feed intake, feeding behavior, and growth traits was performed in an F2 population derived from a cross between Chinese Meishan and European Large White pigs. A QTL with a significant effect on daily feed intake (DFI) was identified on Sus scrofa Chromosome 2 (SSC2). A number of suggestive QTL with effects on daily gain, feed conversion, and feeding behavior traits were also located. The significant QTL lies close to a previously identified mutation in the insulin-like growth factor 2 gene (IGF2) that affects carcass composition traits, although the IGF2 mutation is not segregating in the populations analyzed in the current study. Therefore, a distinct causal variant may exist on the P arm of SSC2 with an effect on feed intake.
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Acknowledgments
The authors are indebted to the staff at Dryden Farm (Roslin) for care of the animals and data collection. They thank Rosalie Waldron, Heather Finlayson, Alison Downing, and Jen Anderson for technical assistance. This project was supported through the LINK SLP program, with funding from DEFRA, MLC, Cotswold Pig Development Company Ltd., JSR Healthbred Ltd., Newsham Hybrid Pigs Ltd., Rattlerow Farms, and PIC.
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Houston, R.D., Haley, C.S., Archibald, A.L. et al. A QTL affecting daily feed intake maps to Chromosome 2 in pigs. Mamm Genome 16, 464–470 (2005). https://doi.org/10.1007/s00335-004-4026-0
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DOI: https://doi.org/10.1007/s00335-004-4026-0