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Multidetector CT angiography in the assessment of peripheral arterial occlusive disease: accuracy in detecting the severity, number, and length of stenoses

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Abstract

The purpose was to evaluate the accuracy of multidetector CT angiography (MD-CTA) in the morphologic assessment of peripheral arterial occlusive disease (PAOD) compared to digital subtraction angiography (DSA). Fifty consecutive patients referred for DSA of the peripheral arteries due to PAOD were prospectively included in this study and underwent 16-row MD-CTA prior to DSA. Maximum intensity projections and multipath curved planar reformations were created with a semi-automated toolbox. Twenty-one vascular segments were defined in each leg and compared to DSA findings with regard to gradation, length, and number of lesions. Mean sensitivity and specificity in the detection of significant stenoses (over 70%) were 100% and 99.5% in the iliac arteries, 97.4% and 99.0% in the femoro-popliteal arteries, and 98.3% and 99.8% in the infrapopliteal arteries, respectively. High kappa values for exact stenoses gradation (0.74–1), lesion length (0.74–1), and number of lesions (0.71–1) were reached by MD-CTA, indicating high agreement with DSA. Non-invasive MD-CTA is an accurate tool for the assessment of all treatment-relevant morphologic information of PAOD (gradation, length, and number of stenoses) compared to DSA.

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Acknowledgements

This work was supported by Fonds zur Förderung der wissenschaftlichen Forschung (FWF, Austria) under the contract no. L291–N04.

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Authors and Affiliations

  1. Division of Cardiovascular and Interventional Radiology, Department of Radiology, Medical University of Vienna, Vienna, Austria

    R. Schernthaner, A. Stadler, F. Lomoschitz, M. Weber, J. Lammer & Ch. Loewe

  2. Department of Radiology, Stanford University Medical Center, 300 Pasteur Dr., Room S-072, Stanford, CA, 94305-5105, USA

    D. Fleischmann

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  1. R. Schernthaner
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  2. A. Stadler
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  3. F. Lomoschitz
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  4. M. Weber
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  5. D. Fleischmann
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  6. J. Lammer
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  7. Ch. Loewe
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Correspondence to R. Schernthaner.

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Schernthaner, R., Stadler, A., Lomoschitz, F. et al. Multidetector CT angiography in the assessment of peripheral arterial occlusive disease: accuracy in detecting the severity, number, and length of stenoses. Eur Radiol 18, 665–671 (2008). https://doi.org/10.1007/s00330-007-0822-8

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  • DOI: https://doi.org/10.1007/s00330-007-0822-8

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