Abstract
Thirty-seven consecutive patients with elevated PSA levels and negative tumor prostate biopsies underwent a MR-guided prostate biopsy in a 1.5-T scanner in the supine position. After localization of suspected tumor areas using an endorectal coil and two body-phased array coils, the biopsy device was positioned without any repositioning of the patient. The biopsy device consisted of a mount, a ball joint, a positioning stage and an insertion stage with a needle guide, which was filled with a MR-visible fluid to control positioning of the needle using a balanced steady-state free precession sequence (TrueFISP) and a high-resolution turbo spin echo (T2-TSE) sequence. Core biopsies were taken manually in the magnet. The biopsy needle could be correctly positioned in all cases. Suspected lesions with a diameter ≥10 mm could be successfully punctured. Four to nine (mean =6) biopsies were taken per patient. In 14 patients, prostate cancer was confirmed at histology. Twenty-four biopsies positive for cancer were performed in 14 patients. A correct correlation was found between the site of biopsy and histology. MR-guided prostate biopsy can be effective in increasing primary positive tumor biopsy results in patients with a history of negative tumor TRUS-guided prostate biopsies.
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Dennis LK, Resnick MI (2000) Analysis of recent trends in prostate cancer incidence and mortality. Prostate 42:247–252
Beyersdorff D, Winkel A, Hamm B, Lenk S, Loening StA, Taupitz M (2005) MR imaging-guided prostate biopsy with a closed MR unit at 1.5 T: Initial results. Radiology 234:576–581
Wefer AE, Hricak H, Vigneron DB, Coakley FV, Lu Y, Wefer U, Mueller-Lisse U et al (2000) Sextant localization of prostate cancer: comparison of sextant biopsy magnetic Resonance imaging and magnetized resonance spectroscopic imaging with step section histology. J Urol 164:400–404
Ikonen S, Kärkkäinen P, Kivisaari L, Salo JO, Taari K, Vehmas T, Tervahartiala P et al (1998) Magnetic resonance imaging of clinically localized prostate cancer. J Urol 159:915–919
Beyersdorff D, Taupitz M, Winkelmann B, Fischer Th, Lenk S, Loening StA, Hamm B (2002) Patients with a history of elevated prostate-specific antigen levels and negative transrectal US-guided quadrant or sextant biopsy results: value of MR imaging. Radiology 224:701–706
D’Amico AV, Schnall M, Whittington R, Malkowicz SB, Schultz D, Tomaszewski JE, Wein A (1998) Endorectal coil magnetic resonance imaging identifies locally advanced prostate cancer in select patients with clinically localized disease. Urology 51:449–454
Vilanova JC, Comet J, Capdevila A, Barcelo J, Dolz JLI, Huguet M, Barcelo C et al (2001) The value of endorectal MR imaging to predict positive biopsies in clinically intermediate-risk prostate cancer patients. Eur Radiol 11:229–235
Cruz M, Tsuda K, Narumi Y, Kuroiwa Y, Nose T, Kojima Y et al (2002) Characterization of low-intensity lesions in the peripheral zone of prostate on pre-biopsy endorectal coil MR imaging. Eur Radiol 12:357–365
Perrotti M, Han KR, Epstein RE, Kennedy EC, Rabbani F, Badani K (1999) Prospective evaluation of endorectal magnetic resonance imaging to detect tumor foci in men with prior negative prostatic biopsy: a pilot study. J Urol 162:1314–1317
Comet-Batlla J, Vilanova-Busquets JC, Saladie-Roig JM, Gelabert-Mas A, Barcelo-Vidal C (2003) The value of endorectal MRI in the early diagnosis of prostate cancer. Eur Urol 44:201–208
Engelhard K, Hollenbach HP, Deimling M, Kreckel M, Riedl C (2000) Combination of signal intensity measurements of lesions in the peripheral zone of prostate with MRI and serum PSA level for differentiating benign disease from prostate cancer. Eur Radiol 10:1947–1953
Kiessling F, Lichy M, Grobholz R, Heilmann M, Farhan N, Michel MS, Trojan L et al (2004) Simple models improve the discrimination of prostate cancers from the peripheral gland by T1-weighted dynamic MRI. Eur Radiol 14:1793–1801
Cooksen MS et al (2000) Update on transrectal ultrasound-guided needle biopsy of the prostate. Mol Urol 4:93–97
Uzzo RG, Wie JT, Waldbaum RS, Perlmutter AP, Byrne JC, Vaughan ED (1995) The influence of prostate size on cancer detection. J Urol 152:2304–2307
Keetch DW, Catalona WJ, Smith DS (1995) Serial prostatic biopsies in men with persistently elevated serum prostate specific antigen values. J Urol 6:1571–1574
Kimberly A, Roehl JO, Ann V, Catalona A, Catalona WJ (2002) Serial biopsy results In prostate cancer screening study. J Urol 167:2435–2439
Rørvik J, Haukaas S (2001) Magnetic resonance imaging of the prostate. Curr Opin Urol 11:181–188
Quint LE, Van Erp JS, Bland PH, Del Buono EA, Mandell StH, Grossman HB, Gikas PW (1991) Prostate cancer: correlation of MR images with tissue optical density at pathologic examination. Radiology 179:837–842
Hata N, Jinzaki M, Kacher D, Cormak R, Gering D, Nabavi A, Silverman StG et al (2001) MR imaging-guided prostate biopsy with surgical navigation software: device validation and feasibility. Radiology 220:263–268
Cormack RA, D’Amico AV, Hata N, Silverman S, Weinstein M, Tempany CM (2000) Feasibility of transperineal prostate biopsy under interventional magnetic resonance Guidance. Urology 56:663–664
D’Amico AV, Tempany CM, Cormack R, Hata N, Jinzaki M, Tuncali K, Weinstein M et al. (2000) Transperineal magnetic resonance image guided prostate biopsy. J Urol 104:385–387
Susil RC, Camphausen K, Choyke P, Elliot R, McVeigh ER, Gustafson GS, Ning H et al (2004) System for prostate brachytherapy and biopsy in a standard 1.5-T MRI scanner. Magn Reson Med 52:683–687
Zangos ST, Eichler K, Engelmann K, Ahmed M, Dettmer S, Herzog C, Pegios W et al (2005) MR-guided transgluteal biopsies with an open low-field system in patients with clinically suspected prostate cancer: technique and preliminary results. Eur Radiol 15:174–182
Lopez-Corona E, Ohori M, Scardino PT, Reuter VE, Gonen M, Kattan MW (2003) A Nomogram for predicting a positive repeat prostate biopsy in patients with a previous negative biopsy session. J Urol 170:1184–1188
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Engelhard, K., Hollenbach, H.P., Kiefer, B. et al. Prostate biopsy in the supine position in a standard 1.5-T scanner under real time MR-imaging control using a MR-compatible endorectal biopsy device. Eur Radiol 16, 1237–1243 (2006). https://doi.org/10.1007/s00330-005-0100-6
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DOI: https://doi.org/10.1007/s00330-005-0100-6