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Tumoren der Schilddrüse

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Zusammenfassung

Die Tumoren der Schilddrüse sind fast ausschließlich epithelialer Natur. Während das Adenom der Schilddrüse ein durchaus häufiger Tumor ist, machen die Karzinome der Schilddrüse nur etwa 1% aller menschlichen Malignome aus. Die differenzialdiagnostische Problematik der Unterscheidung Adenom—Karzinom sowie eine Reihe von Varianten und Besonderheiten dieser Tumoren bereiten dem Pathologen regelmäßig beträchtliche Probleme. Der folgende Übersichtsartikel ist der Versuch, einen Leitfaden für die histologische Begutachtung von Schilddrüsentumoren in der täglichen Routinetätigkeit zu geben. Besonderen Stellenwert wird der standardisierten Aufarbeitung der Schilddrüsenoperationspräparate, einem zielgerichteten diagnostischen Vorgehen, dem Einsatz der Immunhistochemie in der Schilddrüsenpathologie sowie dem intraoperativen Gefrierschnitt der Schilddrüse eingeräumt.

Abstract

The vast majority of thyroid tumours are epithelial. In contrast to thyroid adenoma, which is a common tumour, thyroid carcinomas make up only 1% of all human malignancies. Routine pathology is regularly confronted with a differential diagnosis involving thyroid adenoma and carcinoma, as well as particular variants of these tumours. This paper deals with the standardised gross and histological examination, as well as the impact of immunohistochemistry and intraoperative frozen sections on thyroid pathology.

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Authors and Affiliations

  1. Institut für Pathologie, Universitätsklinikum Essen

    K.W. Schmid & S.-Y. Sheu

  2. Klinik für Nuklearmedizin, Universitätsklinikum Essen

    R. Görges

  3. Pathologisches Institut, Universität Innsbruck, Österreich

    C. Ensinger

  4. Institut für Pathologie, Universitäts-Hospital Genf, Schweiz

    M. Tötsch

  5. Mitglied des Westdeutschen Tumorzentrums Essen (WTZE), Institut für Pathologie, Universitätsklinikum Essen, Hufelandstraße 55, 45122 , Essen

    K.W. Schmid

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  1. K.W. Schmid
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  2. S.-Y. Sheu
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  3. R. Görges
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  4. C. Ensinger
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  5. M. Tötsch
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Correspondence to K.W. Schmid.

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Schmid, K., Sheu, SY., Görges, R. et al. Tumoren der Schilddrüse. Pathologe 24, 357–372 (2003). https://doi.org/10.1007/s00292-003-0630-0

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