Skip to main content
Log in

The Implementation of an Acute Pain Service for Patients Undergoing Open Ventral Hernia Repair with Mesh and Abdominal Wall Reconstruction

  • Original Scientific Report
  • Published:
World Journal of Surgery Aims and scope Submit manuscript

Abstract

Introduction

In this retrospective cohort single-institutional study, we report the outcomes of implementing a standardized protocol of multimodal pain management with thoracic epidural analgesia via the acute pain service (APS) for patients undergoing ventral hernia repair with mesh placement and abdominal wall reconstruction.

Methods

The primary outcome evaluated was postoperative 72-h opioid consumption, measured in intravenous morphine equivalents (MEQ). Secondary outcomes included hospital length of stay (LOS) among other outcomes. The two cohorts were the APS versus non-APS group, in which the former cohort had an APS providing epidural and multimodal analgesia and the latter utilized pain management per surgical team, which mostly consisted of opioid therapy. Using1:1 propensity-score-matched cohorts, Wilcoxon signed-rank test was used to calculate the differences in outcomes. A p < 0.05 was considered statistically significant.

Results

There were 83 patients, wherein 51 (61.4%) were in the APS group. Between matched cohorts, the non-APS cohort’s median [quartiles] total opioid consumption during the first three days was 85.6 mg MEQs [58.9, 112.8 mg MEQs]. The APS cohort was 31.7 mg MEQs [16.0, 55.3 mg MEQs] (p < 0.0001). The non-APS hospital LOS median [quartiles] was 5 days [4, 7 days] versus 4 days [4, 5 days] in the APS group (p = 0.01).

Discussion

A dedicated APS was associated with decreased opioid consumption by 75%, as well as a decreased hospital LOS. We report no differences in ICU length of stay, time to oral intake, time to ambulation or time to urinary catheter removal.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

Abbreviations

APS:

Acute pain service

ASA:

American Society of Anesthesiologists

BMI:

Body mass index

ERAS:

Enhanced recovery after surgery

ICU:

Intensive care unit

IRB:

Institutional review board

LOS:

Length of stay

MEQ:

Intravenous morphine equivalents

OR:

Operating room

PO:

Per oral

PRN:

As needed

TEA:

Thoracic epidural analgesia

VHR:

Ventral hernia repair

References

  1. Apfelbaum JL, Chen C, Mehta SS et al (2003) Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged. Anesth Analg 97:534–540 (table of contents)

    Article  Google Scholar 

  2. Gronnier C, Wattier JM, Favre H et al (2012) Risk factors for chronic pain after open ventral hernia repair by underlay mesh placement. World J Surg 36:1548–1554

    Article  Google Scholar 

  3. Ross SW, Wormer BA, Kim M et al (2015) Defining surgical outcomes and quality of life in massive ventral hernia repair: an international multicenter prospective study. Am J Surg 210:801–813

    Article  Google Scholar 

  4. Tsirline VB, Colavita PD, Belyansky I et al (2013) Preoperative pain is the strongest predictor of postoperative pain and diminished quality of life after ventral hernia repair. Am Surg 79:829–836

    Article  Google Scholar 

  5. Perkins FM, Kehlet H (2000) Chronic pain as an outcome of surgery. A review of predictive factors. Anesthesiology 93:1123–1133

    Article  CAS  Google Scholar 

  6. White PF, Kehlet H (2010) Improving postoperative pain management: what are the unresolved issues? Anesthesiology 112:220–225

    Article  Google Scholar 

  7. Kehlet H, Jensen TS, Woolf CJ (2006) Persistent postsurgical pain: risk factors and prevention. Lancet 367:1618–1625

    Article  Google Scholar 

  8. Ueland W, Plymale MA, Davenport DL et al (2019) Perioperative factors associated with pain following open ventral hernia repair. Surg Endosc 33:4102–4108

    Article  Google Scholar 

  9. American Society of Anesthesiologists Task Force on Acute Pain M (2012) Practice guidelines for acute pain management in the perioperative setting: an updated report by the American Society of Anesthesiologists Task Force on Acute Pain Management. Anesthesiology 116:248–273

    Article  Google Scholar 

  10. Guay J, Nishimori M, Kopp S (2016) Epidural local anaesthetics versus opioid-based analgesic regimens for postoperative gastrointestinal paralysis, vomiting and pain after abdominal surgery. Cochrane Database Syst Rev 7:CD001893

    PubMed  Google Scholar 

  11. Said ET, Sztain JF, Abramson WB et al (2018) A dedicated acute pain service is associated with reduced postoperative opioid requirements in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. Anesth Analg 127:1044–1050

    Article  Google Scholar 

  12. Said ET, Sztain JF, Swisher MW, et al (2019) Association of an acute pain service with postoperative outcomes following pancreaticoduodenectomy. J Perioper Pract 30(10):309–314

    Article  Google Scholar 

  13. Warren JA, Stoddard C, Hunter AL et al (2017) Effect of multimodal analgesia on opioid use after open ventral hernia repair. J Gastrointest Surg 21:1692–1699

    Article  Google Scholar 

  14. Duhamel A, Labreuche J, Gronnier C et al (2017) Statistical tools for propensity score matching. Ann Surg 265:E79–E80

    Article  Google Scholar 

  15. Austin PC (2011) Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies. Pharm Stat 10:150–161

    Article  Google Scholar 

  16. Hebert JJ, Abraham E, Wedderkopp N et al (2020) Preoperative factors predict postoperative trajectories of pain and disability following surgery for degenerative lumbar spinal stenosis. Spine (Phila Pa 1976) 45(21):E1421–E1430

  17. Yang MMH, Hartley RL, Leung AA et al (2019) Preoperative predictors of poor acute postoperative pain control: a systematic review and meta-analysis. BMJ Open 9:e025091

    Article  Google Scholar 

  18. Austin PC (2008) A critical appraisal of propensity-score matching in the medical literature between 1996 and 2003. Stat Med 27:2037–2049

    Article  Google Scholar 

  19. Jensen KK, Brondum TL, Leerhoy B et al (2020) Preoperative, single, high-dose glucocorticoid administration in abdominal wall reconstruction: a randomized, double-blinded clinical trial. Surgery 167:757–764

    Article  Google Scholar 

  20. Fischer JP, Nelson JA, Wes AM et al (2014) The use of epidurals in abdominal wall reconstruction: an analysis of outcomes and cost. Plast Reconstr Surg 133:687–699

    Article  CAS  Google Scholar 

  21. Popping DM, Elia N, Van Aken HK et al (2014) Impact of epidural analgesia on mortality and morbidity after surgery: systematic review and meta-analysis of randomized controlled trials. Ann Surg 259:1056–1067

    Article  Google Scholar 

  22. Zhou SL, Helm MC, Goldblatt MI (2019) Epidural anesthesia for post-operative pain is associated with a higher incidence of complications following open ventral hernia repair. Surg Endosc 34(8):3527–3532

    Article  Google Scholar 

  23. Prabhu AS, Krpata DM, Perez A et al (2018) Is it time to reconsider postoperative epidural analgesia in patients undergoing elective ventral hernia repair?: an AHSQC analysis. Ann Surg 267:971–976

    Article  Google Scholar 

  24. Kehlet H, Dahl JB (1993) The value of “multimodal” or “balanced analgesia” in postoperative pain treatment. Anesth Analg 77:1048–1056

    Article  CAS  Google Scholar 

  25. Pergolizzi JV Jr, LeQuang JA, Berger GK et al (2017) The basic pharmacology of opioids informs the opioid discourse about misuse and abuse: a review. Pain Ther 6:1–16

    Article  Google Scholar 

  26. Blatnik JA, Krpata DM, Pesa NL et al (2012) Predicting severe postoperative respiratory complications following abdominal wall reconstruction. Plast Reconstr Surg 130:836–841

    Article  CAS  Google Scholar 

  27. Kane-Gill SL, Rubin EC, Smithburger PL et al (2014) The cost of opioid-related adverse drug events. J Pain Palliat Care Pharmacother 28:282–293

    Article  Google Scholar 

  28. Thanh NX, Chuck AW, Wasylak T et al (2016) An economic evaluation of the enhanced recovery after surgery (ERAS) multisite implementation program for colorectal surgery in Alberta. Can J Surg 59:415–421

    Article  Google Scholar 

  29. Majumder A, Fayezizadeh M, Neupane R et al (2016) Benefits of multimodal enhanced recovery pathway in patients undergoing open ventral hernia repair. J Am Coll Surg 222:1106–1115

    Article  Google Scholar 

  30. Jensen KK, Dressler J, Baastrup NN et al (2019) Enhanced recovery after abdominal wall reconstruction reduces length of postoperative stay: An observational cohort study. Surgery 165:393–397

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

ES participated in patient care, study design, data collection, data analysis and manuscript preparation. RD, EM, TF, MM, JS, WA and MS participated in patient care, data collection and manuscript preparation. GJ and AG participated in patient care, study design and manuscript preparation. RG participated in patient care, study design, data collection, data analysis and manuscript preparation.

Corresponding author

Correspondence to Rodney A. Gabriel.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary information

Below is the link to the electronic supplementary material.

Supplementary file1 (DOCX 13 kb)

Supplementary file1 (DOCX 13 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Said, E.T., Drueding, R.E., Martin, E.I. et al. The Implementation of an Acute Pain Service for Patients Undergoing Open Ventral Hernia Repair with Mesh and Abdominal Wall Reconstruction. World J Surg 45, 1102–1108 (2021). https://doi.org/10.1007/s00268-020-05915-2

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00268-020-05915-2

Navigation