Skip to main content
Log in

Clipless Cholecystectomy: Which Sealer Should be Used?

  • Published:
World Journal of Surgery Aims and scope Submit manuscript

Abstract

Background

The use of the Harmonic Scalpel (HS) for cystic duct ligation began with little data about its efficacy or safety. On the other hand, there is not any literature available about the use of PlasmaKinetic Sealer (PK) for closing the cystic duct in laparoscopic cholecystectomy (LC). Therefore, this study was designed to compare the efficacy and safety of HS and PK for achieving safe closure of the cystic ducts after LC.

Methods

Ninety patients with symptomatic gallstone disease were enrolled in this prospective case control study. The patients were operated with laparoscopic technic and divided into three groups (n = 30) randomly. After the dissection of Calot’s triangle, proximal cystic ducts on common bile ducts were sealed with single surgical clips (SC) in all groups, and in the first group, distal of the cystic ducts also was sealed with single SC and the gallbladders were removed with SC. In the second and third groups, distal of the cystic ducts were sealed with HS and PK, respectively. The gallbladders were removed as sealed cystic ducts with HS and PK. Then, gallbladders were connected to a transducer set and increasing pressure with saline was applied. The bursting pressures of gallbladders were measured and differences between the groups were calculated by using Student’s t test. The value of P < 0.05 was accepted as significant.

Results

In this study, the mean cystic duct bursting pressures were 332.46 ± 4.62 mmHg with SC, 326.56 ± 4.53 mmHg with PK, and 343.06 ± 4.28 mmHg with HS. Differences of the mean cystic duct bursting pressures between the groups were indicated the superior results of HS.

Conclusions

The results of this study indicated that HS is more effective than PK and as safe and effective as SC for cystic duct closure.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Keus F, Broeders IA, van Laarhoven CJ (2006) Gallstone disease: surgical aspects of symptomatic cholecystolithiasis and acute cholecystitis. Best Pract Res Clin Gastroenterol 20:1031–1051

    Article  PubMed  CAS  Google Scholar 

  2. Mufti TS, Ahmad S, Naveed D et al (2007) Laparoscopic cholecystectomy: an early experience at Ayub Teaching Hospital, Abbottabad. J Ayub Med Coll Abbottabad 19:42–44

    PubMed  Google Scholar 

  3. Rohatgi A, Widdison Al (2006) An audit of cystic duct closure in laparoscopic cholecystectomies. Surg Endosc 20:875–877

    Article  PubMed  CAS  Google Scholar 

  4. Yano H, Okada K, Kinuta M et al (2003) Efficacy of absorbable clips compared with metal clips for cystic duct ligation in laparoscopic cholecystectomy. Surg Today 33:18–23

    Article  PubMed  Google Scholar 

  5. Hanazaki K, Igarashi J, Sodeyama H et al (1999) Bile leakage resulting from clip displacement of the cystic duct stump: a potential pitfall of laparoscopic cholecystectomy. Surg Endosc 13:168–171

    Article  PubMed  CAS  Google Scholar 

  6. Nelson TM, Nakashima M, Mulvihill SJ (1992) How secure are laparoscopically placed clips? Arch Surg 127:718–720

    PubMed  CAS  Google Scholar 

  7. Geissler B, Lindemann F, Hausser L et al (1998) Dislocation of clips of the cystic duct stump. Zentralbl Chir 123:102–105

    PubMed  Google Scholar 

  8. Labuski MR, Wise SW (1999) Recurrent abdominal abscess secondary to a dropped laparoscopic clip: CT imaging. Abdom Imaging 24:191–192

    Article  PubMed  CAS  Google Scholar 

  9. Nathanson LK, Easter DW, Cuschieri A (1991) Ligation of the structures of the cystic pedicle during laparoscopic cholecystectomy. Am J Surg 161:350–354

    Article  PubMed  CAS  Google Scholar 

  10. Andrews SM, Lewis JL (1994) Laparoscopic knot substitutes. An assessment of techniques of securing sutures through the laparoscope. Endosc Surg Allied Technol 2:62–65

    PubMed  CAS  Google Scholar 

  11. Leung KL, Kwong KH, Lau WY et al (1996) Absorbable clips for cystic duct ligation in laparoscopic cholecystectomy. Surg Endosc 10:49–51

    Article  PubMed  CAS  Google Scholar 

  12. Humes DJ, Ahmed I, Lobo DN (2010) The pedicle effect and direct coupling: delayed thermal injuries to the bile duct after laparoscopic cholecystectomy. Arch Surg 145:96–98

    Article  PubMed  Google Scholar 

  13. Kapoor VK (2009) Management of bile duct injuries: a practical approach. Am Surg 75:1157–1160

    PubMed  Google Scholar 

  14. Schulze S, Krisitiansen VB, Fischer Hansen B, et al (2002) Sealing of cystic duct with bipolar electrocoagulation. Surg Endosc 16:342–344

    Google Scholar 

  15. Pietrow PK, Weizer AZ, L’Esperance JO et al (2005) PlasmaKinetic bipolar vessel sealing: burst pressures and thermal spread in an animal model. J Endourol 19:107–110

    Article  PubMed  Google Scholar 

  16. Westervelt J (2004) Clipless cholecystectomy: broadening the role of the Harmonic scalpel. J Soc Laproendosc Surg 8:283–285

    Google Scholar 

  17. Tebala GD (2006) Three-port laparoscopic cholecystectomy by harmonic dissection without cystic duct and artery clipping. Am J Surg 9:718–720

    Article  Google Scholar 

  18. Huscher CGS, Lirici MM, Di Paola M et al (2003) Laparoscopic cholecystectomy by ultrasonic dissection without cystic duct and artery ligature. Surg Endosc 17:442–451

    Article  PubMed  CAS  Google Scholar 

  19. Bessa SS, Al-Fayoumi TA, Katri KM et al (2008) Clipless laparoscopic cholecystectomy by ultrasonic dissection. J Laparoendosc Adv Surg Tech A 18:593–598

    Google Scholar 

  20. Vu T, Aguilo R, Marshall NC (2008) Clipless technique of laparoscopic cholecystectomy using the harmonic scalpel. Ann R Coll Surg Engl 90:612

    Article  PubMed  CAS  Google Scholar 

  21. Huscher CGS, Lirici MM, Anastasi A et al (1999) Laparoscopic cholecystectomy by harmonic dissection. Surg Endosc 13:1256–1257

    PubMed  CAS  Google Scholar 

  22. Zhang ZH, Wu SD, Wang B et al (2008) Sphincter of Oddi hypomotility and its relationship with duodenal-biliary reflux, plasma motilin and serum gastrin. World J Gastroenterol 14:4077–4081

    Article  PubMed  CAS  Google Scholar 

  23. Geenen JE, Hogan WJ, Dodds WJ (1987) Sphincter of Oddi. In: Sivak MV Jr (ed) Gastroenterologic endoscopy. WB Saunders, Philadelphia, pp 735–751

  24. Smout AJPM, Akkerrmans LMA (1992) The gallbladder and bile ducts. In: Smout AJPM (ed) Normal and disturbed motility of the gastrointestinal tract. Wrightson Biomedical Pub. Ltd, Petersfield, pp 130–156

    Google Scholar 

  25. Toouli J (2009) Sphincter of Oddi: function, dysfunction, and its management. J Gastroenterol Hepatol 24:57–62

    Article  Google Scholar 

  26. Richardson MC, Bell G, Fullarton GM (1996) Incidence and nature of bile duct injuries following laparoscopic cholecystectomy: an audit of 5913 cases. West of Scotland Laparoscopic Cholecystectomy Audit Group. Br J Surg 83:1356–1360

    Article  PubMed  CAS  Google Scholar 

  27. Amaral JF (1994) The experimental development of an ultrasonically activated scalpel for laparoscopic use. Surg Laparosc Endosc 4:92–99

    PubMed  CAS  Google Scholar 

  28. Minutolo V, Gagliano G, Rinzivillo C et al (2008) Usefulness of the ultrasonically activated scalpel in laparoscopic cholecystectomy: our experience and review of literature. G Chir 29:242–245

    PubMed  CAS  Google Scholar 

  29. Amaral JF, Chrosteek CA (1997) Experimental comparison of the ultrasonically activated scalpel to electrosurgery and laser surgery for laparoscopic use. Min Invasive Ther Allied Technol 6:324–331

    Article  Google Scholar 

  30. Wise Unger S, Glick GL, Landeros M (1996) Cystic duct leak after laparoscopic cholecystectomy. A multi-institutional study. Surg Endosc 10:1189–1193

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Burak Kavlakoglu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kavlakoglu, B., Pekcici, R. & Oral, S. Clipless Cholecystectomy: Which Sealer Should be Used?. World J Surg 35, 817–823 (2011). https://doi.org/10.1007/s00268-010-0819-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00268-010-0819-3

Keywords

Navigation