Abstract
Osteoporosis has been recognised as a public health concern for at least three decades but it has been relatively recent that the push has been for orthopaedic surgeons to take a more active role in the diagnosis and treatment of patients with decreased bone mineral density (BMD). Most often these patients are encountered after they have suffered a fracture making secondary prevention the area where orthopaedists may exert the greatest influence on patient care. The purpose of this article is to provide a succinct framework for the diagnosis and treatment of patients with decreased BMD. Patients are deemed to have decreased BMD if they have suffered a fragility fracture, a fracture caused by a low-energy traumatic event. These patients are often encountered in the emergency department and admitted for further treatment of their fractures or recommended for follow-up in the clinic. Regardless of treatment course these are opportunities for the orthopaedic surgeon to intervene in the osteoporotic disease process and positively affect a patient’s bone health. This article compiles the available literature on osteoporosis and presents it succinctly with the incorporation of both a diagnosis algorithm and treatment profile table. With the use of these two tools, orthopaedic surgeons everywhere should be able to take a more active role in their patients’ bone health.
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References
Johnell O, Kanis JA (2006) An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int 17(12):1726–1733
Office of the Surgeon General (2004) Bone health and osteoporosis: a report of the Surgeon General
Tosi LL, Gliklich R, Kannan K, Koval KJ (2008) The American Orthopaedic Association's “own the bone” initiative to prevent secondary fractures. J Bone Joint Surg Am 90(1):163–173
Kanis JA, Johnell O, De Laet C et al (2004) A meta-analysis of previous fracture and subsequent fracture risk. Bone 35(2):375–382
Wustrack R, Seeman E, Bucci-Rechtweg C et al (2012) Predictors of new and severe vertebral fractures: results from the HORIZON Pivotal Fracture Trial. Osteoporos Int 23(1):53–58
Sorbi R, Aghamirsalim MR (2012) Knowledge of orthopaedic surgeons in managing patients with fragility fracture. Int Orthop 36(6):1275–1279
No authors listed (1993) Consensus development conference: diagnosis, prophylaxis, and treatment of osteoporosis. Am J Med 94 (6):646–650
Ström O, Borgström F, Kanis JA et al (2011) Osteoporosis: burden, health care provision and opportunities in the EU: a report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch Osteoporos 6(1–2):59–155
Abrahamsen B, van Staa T, Ariely R et al (2009) Excess mortality following hip fracture: a systematic epidemiological review. Osteoporos Int 20(10):1633–1650
Bass E, French DD, Bradham DD, Rubenstein LZ (2007) Risk-adjusted mortality rates of elderly veterans with hip fractures. Ann Epidemiol 17(7):514–519
Melton LJ 3rd, Thamer M, Ray NF et al (1997) Fractures attributable to osteoporosis: report from the National Osteoporosis Foundation. J Bone Miner Res 12(1):16–23
Akesson K, Marsh D, Mitchell PJ et al (2013) Capture the Fracture: a Best Practice Framework and global campaign to break the fragility fracture cycle. Osteoporos Int 24(8):2135–2152
Edwards BJ, Bunta AD, Simonelli C et al (2007) Prior fractures are common in patients with subsequent hip fractures. Clin Orthop Relat Res 461:226–230
Dell R, Greene D, Schelkun SR, Williams K (2008) Osteoporosis disease management: the role of the orthopaedic surgeon. J Bone Joint Surg Am 90(Suppl 4):188–194
Giangregorio L, Papaioannou A, Cranney A et al (2006) Fragility fractures and the osteoporosis care gap: an international phenomenon. Semin Arthritis Rheum 35(5):293–305
American Orthopaedic Association (2005) Leadership in orthopaedics: taking a stand to own the bone. American Orthopaedic Association position paper. J Bone Joint Surg Am 87 (6):1389–1391
Borovecki F, Pecina-Slaus N, Vukicevic S (2007) Biological mechanisms of bone and cartilage remodelling–genomic perspective. Int Orthop 31(6):799–805
Bolland MJ, Grey AB, Gamble GD, Reid IR (2010) Effect of osteoporosis treatment on mortality: a meta-analysis. J Clin Endocrinol Metab 95(3):1174–1181
Grey A, Bolland MJ (2013) The effect of treatments for osteoporosis on mortality. Osteoporos Int 24(1):1–6
Dell RM, Greene D, Anderson D, Williams K (2009) Osteoporosis disease management: what every orthopaedic surgeon should know. J Bone Joint Surg Am 91(Suppl 6):79–86
Herrera A, Martinez AA, Ferrandez L et al (2006) Epidemiology of osteoporotic hip fractures in Spain. Int Orthop 30(1):11–14
Bogoch ER, Elliot-Gibson V, Beaton DE et al (2006) Effective initiation of osteoporosis diagnosis and treatment for patients with a fragility fracture in an orthopaedic environment. J Bone Joint Surg Am 88(1):25–34
Edwards BJ, Koval K, Bunta AD et al (2011) Addressing secondary prevention of osteoporosis in fracture care: follow-up to “own the bone”. J Bone Joint Surg Am 93(15):e87
Queally JM, Kiernan C, Shaikh M et al (2013) Initiation of osteoporosis assessment in the fracture clinic results in improved osteoporosis management: a randomised controlled trial. Osteoporos Int 24(3):1089–1094
Gaboury I, Corriveau H, Boire G et al (2013) Partnership for fragility bone fracture care provision and prevention program (P4Bones): study protocol for a secondary fracture prevention pragmatic controlled trial. Implement Sci 8:10
van Helden S, Cals J, Kessels F et al (2006) Risk of new clinical fractures within 2 years following a fracture. Osteoporos Int 17(3):348–354
Center JR, Bliuc D, Nguyen TV, Eisman JA (2007) Risk of subsequent fracture after low-trauma fracture in men and women. JAMA 297(4):387–394
Skedros JG, Holyoak JD, Pitts TC (2006) Knowledge and opinions of orthopaedic surgeons concerning medical evaluation and treatment of patients with osteoporotic fracture. J Bone Joint Surg Am 88(1):18–24
Delmas PD, Marin F, Marcus R et al (2007) Beyond hip: importance of other nonspinal fractures. Am J Med 120(5):381–387
Lems WF (2007) Clinical relevance of vertebral fractures. Ann Rheum Dis 66(1):2–4
National Osteoporosis Foundation (2013) Clinician’s guide to prevention and treatment of osteoporosis. Washington: National Osteoporosis Foundation. http://www.nof.org/hcp/clinicians-guide. 2013
Kanis JA (2014) FRAX WHO fracture risk assessment tool. http://www.shef.ac.uk/FRAX/
Mitchell PJ (2013) Best practices in secondary fracture prevention: fracture liaison services. Curr Osteoporos Rep 11(1):52–60
Ganda K, Puech M, Chen JS et al (2013) Models of care for the secondary prevention of osteoporotic fractures: a systematic review and meta-analysis. Osteoporos Int 24(2):393–406
Black DM, Thompson DE, Bauer DC et al (2000) Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. FIT Research Group. J Clin Endocrinol Metab 85(11):4118–4124
Dell R (2011) Fracture prevention in Kaiser Permanente Southern California. Osteoporos Int 22(Suppl 3):457–460
Newman ED (2011) Perspectives on pre-fracture intervention strategies: the Geisinger Health System Osteoporosis Program. Osteoporos Int 22(Suppl 3):451–455
Curtis JR, Silverman SL (2013) Commentary: the five Ws of a fracture liaison service: why, who, what, where, and how? In osteoporosis, we reap what we sow. Curr Osteoporos Rep 11(4):365–368
White MK, Martin RB, Yeater RA et al (1984) The effects of exercise on the bones of postmenopausal women. Int Orthop 7(4):209–214
Nachtigall MJ, Nazem TG, Nachtigall RH, Goldstein SR (2013) Osteoporosis risk factors and early life-style modifications to decrease disease burden in women. Clin Obstet Gynecol 56(4):650–653
Bischoff-Ferrari HA, Willett WC, Wong JB et al (2005) Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA 293(18):2257–2264
Chung M, Lee J, Terasawa T et al (2011) Vitamin D with or without calcium supplementation for prevention of cancer and fractures: an updated meta-analysis for the U.S. Preventive Services Task Force. Ann Intern Med 155(12):827–838
Bauer DC (2013) Clinical practice. Calcium supplements and fracture prevention. N Engl J Med 369(16):1537–1543
Moyer VA, U.S. Preventive Services Task Force (2013) Vitamin D and calcium supplementation to prevent fractures in adults: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med 158(9):691–696
Watts NB, Bilezikian JP, Camacho PM et al (2010) American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the diagnosis and treatment of postmenopausal osteoporosis. Endocr Pract 16(Suppl 3):1–37
Institute of Medicine Committee to Review Dietary Reference Intakes for Vitamin D and Calcium et al (2011) The National Academies collection: reports funded by National Institutes of Health. In: Ross AC, Taylor CL, Yaktine AL (eds) Dietary reference intakes for calcium and vitamin D. National Academies Press (US) National Academy of Sciences, Washington
Sommer I, Erkkilä AT, Järvinen R et al (2013) Alcohol consumption and bone mineral density in elderly women. Public Health Nutr 16(4):704–712
Ward KD, Klesges RC (2001) A meta-analysis of the effects of cigarette smoking on bone mineral density. Calcif Tissue Int 68(5):259–270
Kelley GA, Kelley KS, Tran ZV (2002) Exercise and lumbar spine bone mineral density in postmenopausal women: a meta-analysis of individual patient data. J Gerontol A Biol Sci Med Sci 57(9):M599–M604
Kelley GA, Kelley KS, Kohrt WM (2012) Effects of ground and joint reaction force exercise on lumbar spine and femoral neck bone mineral density in postmenopausal women: a meta-analysis of randomized controlled trials. BMC Musculoskelet Disord 13:177
Kohrt WM, Bloomfield SA, Little KD et al (2004) American College of Sports Medicine Position Stand: physical activity and bone health. Med Sci Sports Exerc 36(11):1985–1996
Henderson SA, Graham HK, Mollan RA et al (1989) Calcium homeostasis and exercise. Int Orthop 13(1):69–73
Gillespie LD, Robertson MC, Gillespie WJ et al (2012) Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev 9:CD007146
Bergland A, Jarnlo GB, Laake K (2003) Predictors of falls in the elderly by location. Aging Clin Exp Res 15(1):43–50
Leslie WD, Giangregorio LM, Yogendran M et al (2012) A population-based analysis of the post-fracture care gap 1996–2008: the situation is not improving. Osteoporos Int 23(5):1623–1629
Giammattei F, Giammattei J, Howland V (2009) Physician follow-up care for osteoporosis after fragility fractures. Phys Sportsmed 37(4):62–67
Marsh D, Akesson K, Beaton DE et al (2011) Coordinator-based systems for secondary prevention in fragility fracture patients. Osteoporos Int 22(7):2051–2065
Cooper MS, Palmer AJ, Seibel MJ (2012) Cost-effectiveness of the Concord Minimal Trauma Fracture Liaison service, a prospective, controlled fracture prevention study. Osteoporos Int 23(1):97–107
McLellan AR, Wolowacz SE, Zimovetz EA et al (2011) Fracture liaison services for the evaluation and management of patients with osteoporotic fracture: a cost-effectiveness evaluation based on data collected over 8 years of service provision. Osteoporos Int 22(7):2083–2098
Sander B, Elliot-Gibson V, Beaton DE et al (2008) A coordinator program in post-fracture osteoporosis management improves outcomes and saves costs. J Bone Joint Surg Am 90(6):1197–1205
Centers for Medicare & Medicaid Services (2014) MEDICARE “PAY FOR PERFORMANCE (P4P)” INITIATIVES. http://www.cms.gov/apps/media/press/release.asp?counter=1343
Black DM, Cummings SR, Karpf DB et al (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 348(9041):1535–1541
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Farmer, R.P., Herbert, B., Cuellar, D.O. et al. Osteoporosis and the orthopaedic surgeon: basic concepts for successful co-management of patients’ bone health. International Orthopaedics (SICOT) 38, 1731–1738 (2014). https://doi.org/10.1007/s00264-014-2317-y
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DOI: https://doi.org/10.1007/s00264-014-2317-y