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Particle migration and gap healing around trabecular metal implants

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Abstract

Bone on-growth and peri-implant migration of polyethylene particles were studied in an experimental setting using trabecular metal and solid metal implants. Cylindrical implants of trabecular tantalum metal and solid titanium alloy implants with a glass bead blasted surface were inserted either in an exact surgical fit or with a peri-implant gap into a canine knee joint. We used a randomised paired design. Polyethylene particles were injected into the knee joint. In both types of surgical fit we found that the trabecular metal implants had superior bone ongrowth in comparison with solid metal implants (exact fit: 23% vs. 7% [p=0.02], peri-implant gap: 13% vs. 0% [p=0.02]. The number of peri-implant polyethylene particles was significantly reduced around the trabecular metal implants with a peri-implant gap compared with solid implants.

Résumé

Dans un cadre expérimental, nous avons étudié la réhabitation osseuse et la migration péri-implant de particules de polyéthylène en utilisant des implants en métal trabéculaire et des implants en métal massif. Des implants cylindriques de tantale trabéculaire et des implants en alliage de titane massif avec traitement de surface ont été inséré avec une adaptation exacte ou avec un espace péri-implant dans des genoux de chiens. Nous avons utilisé une forme randomisée par paire. Des particules de polyéthylène ont été injectées dans le genou. Dans les deux types d'implantation nous avons trouvé que les implants en métal trabéculaire avaient une réhabitation osseuse supérieure en comparaison des implants en métal massif. Le nombre de particules de polyéthylène était notablement réduit autour de l'implant en métal trabéculaire avec un intervalle péri-implant comparé aux implants en métal massif.

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Acknowledgements

The authors wish to thank Annette Milton and Jane Pauli for their technical expertise in preparing the histological sections. Zimmer Inc., Warsaw, IN, USA produced the implants free of charge. Smith and Nephew-Richards provided the polyethylene particles. Niels Osterby Olesen, Associate Professor, MSc, Earth Sciences, University of Aarhus, performed the SEM. Dr. Lennart Larsson, PhD, Department of Medical Microbiology, Dermatology and Infection, Lund University, Sweden, performed the analysis of PE particles for endotoxins. The Danish Medical Research Council, The Danish Rheumatism Association and Institute of Experimental Clinical Research, University of Aarhus, Denmark, financially supported the study.

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Authors and Affiliations

  1. Orthopedic Research Laboratory, Aarhus University Hospital, Nørrebrogade 44, Building 1A, 8000, Aarhus, Denmark

    O. Rahbek, S. Kold, B. Zippor & K. Søballe

  2. Institute of Experimental Clinical Research, Aarhus University Hospital, Brendstrupgårdsvej 100, 8200, Aarhus, Denmark

    O. Rahbek, S. Kold, B. Zippor & K. Søballe

  3. Department of Orthopedics, Aarhus University Hospital, Nørrebrogade 44, 8000, Aarhus, Denmark

    O. Rahbek, S. Kold, B. Zippor & K. Søballe

  4. Department of Orthopedics, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense, Denmark

    S. Overgaard

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  1. O. Rahbek
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  2. S. Kold
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  3. B. Zippor
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  4. S. Overgaard
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  5. K. Søballe
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Correspondence to O. Rahbek.

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Rahbek, O., Kold, S., Zippor, B. et al. Particle migration and gap healing around trabecular metal implants. International Orthopaedics (SICO 29, 368–374 (2005). https://doi.org/10.1007/s00264-005-0008-4

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  • DOI: https://doi.org/10.1007/s00264-005-0008-4

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