Skip to main content

Advertisement

SpringerLink
Log in

Schnitzler’s syndrome: 3-year radiological follow-up

  • Case Report
  • Published:
Skeletal Radiology Aims and scope Submit manuscript

Abstract

Schnitzler’s syndrome comprises urticaria, monoclonal gammapathy, inflammatory signs (fever, enlarged lymph nodes, hyperleukocytosis), and bone lesions. We report the imaging findings and follow-up of a new case with extensive osteosclerosis of the iliac bone, associated with inflammatory signal changes on MRI and foci of increased uptake on bone scintigraphy. When a diagnosis of Schnitzler’s syndrome is established, treatment should be towards symptoms only; a long follow-up is warranted, as a delayed evolution towards a lymphoproliferative syndrome is possible.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Lipsker D, Veran Y, Grunenberger F, Cribier B, Heid E, Grosshans G. The Schnitzler syndrome. Medicine 2001;80:37–44

    Article  PubMed  CAS  Google Scholar 

  2. Lecompte M, Blais G, Bisson G, Maynard B. Schnitzler’s syndrome. Skelet Radiol 1998;27:294–6

    Article  CAS  Google Scholar 

  3. De Waele S, Lecouvet F, Malghem J, Jamar F, Lambert M. Schnitzler’s syndrome: an unusual cause of bone pain with suggestive imaging features. Am J Roentgenol 2000;175:1325–7

    Google Scholar 

  4. Paulin P, Cusset C, Jacquelin L, Pages JM, Chapalain JC. Syndrome de Schnitzler. Une nouvelle observation. Presse Med 1992;21:1758–61

    PubMed  CAS  Google Scholar 

  5. Schnitzler L, Hurez D, Verret JL. Urticaire chronique-Ostéocondensation-Macroglobulinémie. Ann Dermatol Venereol 1989;116:547–50

    PubMed  CAS  Google Scholar 

  6. Puddu P, Cianchini G, Girardelli CR, Colonna L, Gatti S, De Pitta O. Schnitzler’s syndrome: report of a new case and a review of the literature. Clin Exp Rheumatol 1997;15:91–5

    PubMed  CAS  Google Scholar 

  7. Goupille P, Pizzuti P, Diot E, Jattiot F, Guilmot JL, Valat JP. Schnitzler’s syndrome (urticaria and macroglobulinemia) dramatically improved with corticosteroïds. Clin Exp Rheumatol 1995;13:95–8

    PubMed  CAS  Google Scholar 

  8. Jajic Z, Jajic I, Nemcic T. Primary hypertrophic osteoarthropathy: clinical, radiologic, and scintigraphic characteristics. Arch Med Res 2001;32:136–42

    Article  PubMed  CAS  Google Scholar 

  9. Michel JL, Gaucher-Hugel AS, Reynier C et al. POEMS syndrome: imaging of skeletal manifestations, a study of 8 cases. J Radiol 2003;84:393–7

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, Hôpital Bichat, 46 rue Henri Huchard, 75018, Paris, France

    A. Bertrand & A. Feydy

  2. Department of Internal Medicine, Hôpital Beaujon, 100 boulevard du Général Leclerc, 92110, Clichy, France

    N. Belmatoug & B. Fantin

Authors
  1. A. Bertrand
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Feydy
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. Belmatoug
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. B. Fantin
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A. Feydy.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bertrand, A., Feydy, A., Belmatoug, N. et al. Schnitzler’s syndrome: 3-year radiological follow-up. Skeletal Radiol 36, 153–156 (2007). https://doi.org/10.1007/s00256-006-0093-5

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00256-006-0093-5

Keywords

Search

Navigation