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2004 Nomenclature for the chicken major histocompatibility (B and Y ) complex

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Abstract

The first standard nomenclature for the chicken (Gallus gallus) major histocompatibility (B) complex published in 1982 describing chicken major histocompatibility complex (MHC) variability is being revised to include subsequent findings. Considerable progress has been made in identifying the genes that define this polymorphic region. Allelic sequences for MHC genes are accumulating at an increasing rate without a standard system of nomenclature in place. The recommendations presented here were derived in workshops held during International Society of Animal Genetics and Avian Immunology Research Group meetings. A nomenclature for B and Y (Rfp-Y) loci and alleles has been developed that can be applied to existing and newly defined haplotypes including recombinants. A list of the current standard B haplotypes is provided with reference stock, allele designations, and GenBank numbers for corresponding MHC class I and class IIβ sequences. An updated list of proposed names for B recombinant haplotypes is included, as well as a list of over 17 Y haplotypes designated to date.

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Acknowledgements

The authors gratefully acknowledge the help of H. Abplanalp, G. Dambrine, M.E. Delany, H. Juin, H. Juul-Madsen, S.J. Lamont, O. Lassila, J. Marsh, G.T. Pharr, J. Plachy, J. Salomonsen, R.L. Taylor, Jr, O. Vainio, and M. Vilhelmova in identifying and defining the existing MHC-defined experimental lines. Anonymous reviewers are thanked for their suggestions. The authors gratefully acknowledge that portions of this nomenclature were patterned after the Nomenclature for Factors of the HLA system compiled by S.G.E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System. An earlier version of this nomenclature appeared in the Proceedings of the 6th Avian Immunology Research Group Meeting (Cornell, 2000). Current members of the Nomenclature Committee are: S.J. Ewald (ewaldsj@vetmed.auburn.edu), H.D. Hunt (hunthd@pilot.msu.edu), J. Kaufman (jim.kaufman@bbsrc.ac.uk), M.M. Miller (mamiller@coh.org), and R. Zoorob (zoorob@infobiogen.fr).

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Authors and Affiliations

  1. Beckman Research Institute, City of Hope National Medical Center, 1450 E. Duarte Road, Duarte, CA 91010, USA

    Marcia M. Miller

  2. Avian Disease and Oncology Laboratory, USDA-ARS, East Lansing, MI 48823, USA

    Larry D. Bacon & Henry D. Hunt

  3. Medical University of Innsbruck, 6020 , Innsbruck, Austria

    Karel Hala

  4. Auburn University, Auburn, AL 36849, USA

    Sandra J. Ewald

  5. Institute for Animal Health, Compton, Newbury, Berkshire, RG20 7NN, UK

    Jim Kaufman

  6. CNRS, 19 rue Guy Moquet, BP 8, 94801, Villejuif Cedex, France

    Rima Zoorob

  7. Northern Illinois University, IL 60115, DeKalb, USA

    W. Elwood Briles

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  2. Larry D. Bacon
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  3. Karel Hala
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Correspondence to Marcia M. Miller.

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Miller, M.M., Bacon, L.D., Hala, K. et al. 2004 Nomenclature for the chicken major histocompatibility (B and Y ) complex. Immunogenetics 56, 261–279 (2004). https://doi.org/10.1007/s00251-004-0682-1

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  • DOI: https://doi.org/10.1007/s00251-004-0682-1

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