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Revised ultrasound criteria for appendicitis in children improve diagnostic accuracy

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Abstract

Background

Use of CT in the evaluation of suspected appendicitis in children is common. Expanding the use of US would eliminate the radiation exposure associated with CT.

Objective

We describe new criteria that improve US’s diagnostic accuracy for appendicitis, making it more comparable to CT in terms of sensitivity and specificity.

Materials and methods

We conducted a retrospective review of 304 consecutive patients undergoing US for the diagnosis of appendicitis in our institution during 2006. The sensitivity, specificity and accuracy of the maximal outer diameter (MOD) at various measurements was calculated and compared to pathology results. Additional variables (appendiceal wall thickness, fecalith, hyperemia, fat stranding, free fluid, age and weight) were also evaluated.

Results

The highest sensitivity (98.7%) and specificity (95.4%) were identified when MOD was ≥7 mm or wall thickness was >1.7 mm. These values resulted in correctly classifying 96.6% of cases, with 1 (0.5%) false-negative and 6 (2.9%) false-positive studies. Incorporating secondary signs of appendicitis, age or weight did not alter accuracy.

Conclusion

These findings identify new US criteria that compare favorably to CT. In children with suspected appendicitis, using US as the initial imaging study will ultimately lead to improved accuracy, lower cost and the elimination of ionizing radiation exposure.

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References

  1. Reed MH (2008) Imaging utilization commentary: a radiology perspective. Pediatr Radiol 38(Suppl 4):S660–663

    Article  PubMed  Google Scholar 

  2. Worrell JA, Drolshagen LF, Kelly TC et al (1990) Graded compression ultrasound in the diagnosis of appendicitis. A comparison of diagnostic criteria. J Ultrasound Med 9:145–150

    PubMed  CAS  Google Scholar 

  3. Schulte B, Beyer D, Kaiser C et al (1998) Ultrasonography in suspected acute appendicitis in childhood-report of 1285 cases. Eur J Ultrasound 8:177–182

    Article  PubMed  CAS  Google Scholar 

  4. Spear R, Kimmey MB, Wang KY et al (1992) Appendiceal US scans: histologic correlation. Radiology 183:831–834

    PubMed  CAS  Google Scholar 

  5. Sivit CJ (1993) Diagnosis of acute appendicitis in children: spectrum of sonographic findings. AJR 161:147–152

    PubMed  CAS  Google Scholar 

  6. Vignault F, Filiatrault D, Brandt ML et al (1990) Acute appendicitis in children: evaluation with US. Radiology 176:501–504

    PubMed  CAS  Google Scholar 

  7. Jeffrey RB Jr, Laing FC, Townsend RR (1988) Acute appendicitis: sonographic criteria based on 250 cases. Radiology 167:327–329

    PubMed  Google Scholar 

  8. Birnbaum BA, Wilson SR (2000) Appendicitis at the millennium. Radiology 215:337–348

    PubMed  CAS  Google Scholar 

  9. Rettenbacher T, Hollerweger A, Macheiner P et al (2001) Outer diameter of the vermiform appendix as a sign of acute appendicitis: evaluation at US. Radiology 218:757–762

    PubMed  CAS  Google Scholar 

  10. Kessler N, Cyteval C, Gallix B et al (2004) Appendicitis: evaluation of sensitivity, specificity, and predictive values of US, Doppler US, and laboratory findings. Radiology 230:472–478

    Article  PubMed  Google Scholar 

  11. Puylaert JB (1986) Acute appendicitis: US evaluation using graded compression. Radiology 158:355–360

    PubMed  CAS  Google Scholar 

  12. Lim HK, Lee WJ, Kim TH et al (1996) Appendicitis: usefulness of color Doppler US. Radiology 201:221–225

    PubMed  CAS  Google Scholar 

  13. Wiersma F, Toorenvliet BR, Bloem JL et al (2009) US examination of the appendix in children with suspected appendicitis: the additional value of secondary signs. Eur Radiol 19:455–461

    Article  PubMed  Google Scholar 

  14. Brennan GDG (2006) Pediatric appendicitis: pathophysiology and appropriate use of diagnostic imaging. CJEM 8:425–432

    PubMed  Google Scholar 

  15. Scholer SJ, Pituch K, Orr DP et al (1996) Clinical outcomes of children with acute abdominal pain. Pediatrics 98:680–685

    PubMed  CAS  Google Scholar 

  16. Sivit CJ, Applegate KE (2003) Imaging of acute appendicitis in children. Semin Ultrasound CT MR 24:74–82

    Article  PubMed  Google Scholar 

  17. Holscher HC, Heij HA (2009) Imaging of acute appendicitis in children: EU versus U.S. ... or US versus CT? A European perspective. Pediatr Radiol 39:497–499

    Article  PubMed  Google Scholar 

  18. Frush DP, Frush KS, Oldham KT (2009) Imaging of acute appendicitis in children: EU versus U.S. ... or US versus CT? A North American perspective. Pediatr Radiol 39:500–505

    Article  PubMed  Google Scholar 

  19. Doria AS (2009) Optimizing the role of imaging in appendicitis. Pediatr Radiol 39(Suppl 2):S144–148

    Article  PubMed  Google Scholar 

  20. Balthazar EJ, Megibow AJ, Hulnick D et al (1986) CT of appendicitis. AJR 147:705–710

    PubMed  CAS  Google Scholar 

  21. Balthazar EJ, Megibow AJ, Gordon RB et al (1988) Computed tomography of the abnormal appendix. J Comput Assist Tomogr 12:595–601

    Article  PubMed  CAS  Google Scholar 

  22. Balthazar EJ, Gordon RB (1989) CT of appendicitis. Semin Ultrasound CT MR 10:326–340

    PubMed  CAS  Google Scholar 

  23. Balthazar EJ, Megibow AJ, Siegel SE et al (1991) Appendicitis: prospective evaluation with high-resolution CT. Radiology 180:21–24

    PubMed  CAS  Google Scholar 

  24. Friday JH (2006) Update on appendicitis: diagnosis and presurgical management. Curr Opin Pediatr 18:234–238

    Article  PubMed  Google Scholar 

  25. Hagendorf BA, Clarke JR, Burd RS (2004) The optimal initial management of children with suspected appendicitis: a decision analysis. J Pediatr Surg 39:880–885

    Article  PubMed  Google Scholar 

  26. Peña BM, Taylor GA, Fishman SJ et al (2000) Costs and effectiveness of ultrasonography and limited computed tomography for diagnosing appendicitis in children. Pediatrics 106:672–676

    Article  PubMed  Google Scholar 

  27. Peña BM, Taylor GA, Lund DP et al (1999) Effect of computed tomography on patient management and costs in children with suspected appendicitis. Pediatrics 104:440–446

    Article  PubMed  Google Scholar 

  28. Rao PM, Rhea JT, Novelline RA et al (1998) Effect of computed tomography of the appendix on treatment of patients and use of hospital resources. N Engl J Med 338:141–146

    Article  PubMed  CAS  Google Scholar 

  29. Martin AE, Vollman D, Adler B et al (2004) CT scans may not reduce the negative appendectomy rate in children. J Pediatr Surg 39:886–890, discussion 886–890

    Article  PubMed  Google Scholar 

  30. (2008) Radiation risks and pediatric computed tomography (CT): a guide for health care providers. Available via the National Cancer Institute. http://www.cancer.gov/cancertopics/causes/radiation-risks-pediatric-CT. Accessed 07 Feb 2011

  31. Rice HE, Frush DP, Farmer D et al (2007) Review of radiation risks from computed tomography: essentials for the pediatric surgeon. J Pediatr Surg 42:603–607

    Article  PubMed  Google Scholar 

  32. Rice HE, Frush DP, Harker MJ et al (2007) Peer assessment of pediatric surgeons for potential risks of radiation exposure from computed tomography scans. J Pediatr Surg 42:1157–1164

    Article  PubMed  Google Scholar 

  33. Flum DR, Morris A, Koepsell T et al (2001) Has misdiagnosis of appendicitis decreased over time? A population-based analysis. JAMA 286:1748–1753

    Article  PubMed  CAS  Google Scholar 

  34. Lintula H, Kokki H, Kettunen R et al (2009) Appendicitis score for children with suspected appendicitis. A randomized clinical trial. Langenbecks Arch Surg 394:999–1004

    Article  PubMed  Google Scholar 

  35. Kaiser S, Frenckner B, Jorulf HK (2002) Suspected appendicitis in children: US and CT—a prospective randomized study. Radiology 223:633–638

    Article  PubMed  Google Scholar 

  36. Hernandez JA, Swischuk LE, Angel CA et al (2005) Imaging of acute appendicitis: US as the primary imaging modality. Pediatr Radiol 35:392–395

    Article  PubMed  Google Scholar 

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Correspondence to Adam B. Goldin.

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Goldin, A.B., Khanna, P., Thapa, M. et al. Revised ultrasound criteria for appendicitis in children improve diagnostic accuracy. Pediatr Radiol 41, 993–999 (2011). https://doi.org/10.1007/s00247-011-2018-2

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  • DOI: https://doi.org/10.1007/s00247-011-2018-2

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