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Acute Exposure to Glyphosate Herbicide Affects Oxidative Parameters in Piava (Leporinus obtusidens)

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Abstract

In recent years, commercial glyphosate herbicide formulations have been widely used in agriculture to control aquatic weeds. These pesticides may result in disruption of ecological balance, causing damage to nontarget organisms including fish. Teleostean fish (Leporinus obtusidens) were exposed to commercial glyphosate herbicide formulation at 0 (control), 3, 6, 10 or 20 mg L−1 for 96 h. The effects of herbicide on plasmatic metabolic parameters, thiobarbituric acid reactive substances (TBARS), catalase activity, protein carbonyl, and mucus layer parameters were studied. Plasmatic glucose and lactate levels increased but protein levels showed reduction after herbicide exposure. TBARS levels in brain showed a reduction at all tested concentrations. However, liver demonstrated increased TBARS levels at all tested concentrations, whereas in white muscle TBARS production did not change after exposure to herbicide. Fish exposed to all concentrations of glyphosate showed increase in liver catalase activity and protein carbonyl. Herbicide exposure increased protein and carbohydrate levels of the mucus layer at all tested concentrations. The present results showed that, in 96 h, glyphosate changed toxicological parameters analyzed in piava. Parameters measured in this study may be useful in environmental biomonitoring.

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Authors and Affiliations

  1. Adaptive Biochemistry Laboratory, Department of Chemistry, Federal University of Santa Maria, Santa Maria, RS, Brazil

    Lissandra Glusczak, Vania Lucia Loro, Alexandra Pretto, Bibiana Silveira Moraes, Alice Raabe, Marta Frescura Duarte, Milene Braga da Fonseca, Charlene Cavalheiro de Menezes & Dênia Mendes de Sousa Valladão

  2. Institute of Health Sciences, Federal University of Mato Grosso, 78.550.000, Sinop, MT, Brazil

    Lissandra Glusczak

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  1. Lissandra Glusczak
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  2. Vania Lucia Loro
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  3. Alexandra Pretto
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  4. Bibiana Silveira Moraes
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  5. Alice Raabe
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  6. Marta Frescura Duarte
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  7. Milene Braga da Fonseca
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  8. Charlene Cavalheiro de Menezes
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Correspondence to Lissandra Glusczak.

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Glusczak, L., Loro, V.L., Pretto, A. et al. Acute Exposure to Glyphosate Herbicide Affects Oxidative Parameters in Piava (Leporinus obtusidens). Arch Environ Contam Toxicol 61, 624–630 (2011). https://doi.org/10.1007/s00244-011-9652-4

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  • DOI: https://doi.org/10.1007/s00244-011-9652-4

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