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A novel ionic liquid-modified organic-polymer monolith as the sorbent for in-tube solid-phase microextraction of acidic food additives

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Abstract

A novel ionic liquid-modified organic-polymer monolithic capillary column was prepared and used for in-tube solid-phase microextraction (SPME) of acidic food additives. The primary amino group of 1-aminopropyl-3-methylimidazolium chloride was reacted with the epoxide group of glycidyl methacrylate. The as-prepared new monomer was then copolymerized in situ with acrylamide and N,N’-methylenebisacrylamide in the presence of polyethylene glycol (PEG)-8000 and PEG-10,000 as porogens. The extraction performance of the developed monolithic sorbent was evaluated for benzoic acid, 3-hydroxybenzoic acid, cinnamic acid, 2,4-dichlorophenoxyacetic acid, and 3-(trifluoromethyl)-cinnamic acid. Such a sorbent, bearing hydrophobic and anion-exchange groups, had high extraction efficiency towards the test compounds. The adsorption capacities for the analytes dissolved in water ranged from 0.18 to 1.74 μg cm−1. Good linear calibration curves (R 2 > 0.99) were obtained, and the limits of detection (S/N = 3) for the analytes were found to be in the range 1.2–13.5 ng mL−1. The recoveries of five acidic food additives spiked in Coca-Cola beverage samples ranged from 85.4 % to 98.3 %, with RSD less than 6.9 %. The excellent applicability of the ionic liquid (IL)-modified monolithic column was further tested by the determination of benzoic acid content in Sprite samples, further illustrating its good potential for analyzing food additives in complex samples.

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Acknowledgements

The Project is supported by Zhejiang Provincial Natural Science Foundation of China (LQ12B05001), Ningbo Natural Science Foundation of China (2012A610091), and Ningbo Science and Technology Innovation Team (2011B82002).

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Authors and Affiliations

  1. College of Chemical Engineering, Ningbo University of Technology, Ningbo, 315016, China

    Ting-Ting Wang, Min-Jie Hu, Ying Li, Jiang-Hua Fang & Hao-Qi Gao

  2. Xiangshan Entry-Exit Inspection and Quarantine, Xiangshan, 310014, China

    Yi-Hui Chen

  3. Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA

    Jun-Feng Ma

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  1. Ting-Ting Wang
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  2. Yi-Hui Chen
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  3. Jun-Feng Ma
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  4. Min-Jie Hu
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  5. Ying Li
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  6. Jiang-Hua Fang
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  7. Hao-Qi Gao
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Correspondence to Ting-Ting Wang.

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Wang, TT., Chen, YH., Ma, JF. et al. A novel ionic liquid-modified organic-polymer monolith as the sorbent for in-tube solid-phase microextraction of acidic food additives. Anal Bioanal Chem 406, 4955–4963 (2014). https://doi.org/10.1007/s00216-014-7923-4

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  • DOI: https://doi.org/10.1007/s00216-014-7923-4

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