Skip to main content
SpringerLink
Log in

Re: Tarazona et al. (2017): Glyphosate toxicity and carcinogenicity: a review of the scientific basis of the European Union assessment and its differences with IARC. doi: 10.1007/s00204-017-1962-5

  • Reply
  • Published:
Archives of Toxicology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • BAuA (2016) Proposal for harmonised classification and labelling. Based on Regulation (EC) No 1272/2008 (CLP Regulation), Annex VI, Part 2. Substance Name: N-(phosphonomethyl)glycine; Glyphosate (ISO). European Chemicals Agency http://echa.europa.eu/documents/10162/13626/clh_report_glyphosate_en.pdf

  • European Food Safety Authority (2015) Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate. EFSA J 13:4302–4302

    Article  Google Scholar 

  • Fung KY, Krewski D, Smythe RT (1996) A comparison of tests for trend with historical controls in carcinogen bioassay. Can J Stat 24:431–454

    Article  Google Scholar 

  • Germany (2015) Final addendum to the renewal assessment report on glyphosate, compiled by EFSA

  • Greim H, Gelbke H-P, Reuter U, Thielmann HW, Edler L (2003) Evaluation of historical control data in carcinogenicity studies. Hum Exp Toxicol 22:541–549

    Article  CAS  PubMed  Google Scholar 

  • Greim H, Saltmiras D, Mostert V, Strupp C (2015) Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol 45:185–208

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Haseman JK (1984) Statistical issues in the design, analysis and interpretation of animal carcinogenicity studies. Environ Health Perspect 58:385–392

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • OECD (2009) Carcinogenicity studies. OECD Guideline No. 451. http://www.oecd-ilibrary.org/environment/test-no-451-carcinogenicity-studies_9789264071186-en;jsessionid=17ikkmub37voi.x-oecd-live-02

  • OECD (2012) Guidance document 116 on the conduct and design of chronic toxicity and carcinogenicity studies, supporting test guidelines 451, 452 and 453, 2nd edn. Series on testing and assessment No 116. Env/jm/mono(2011)47

  • Peddada SD, Dinse GE, Kissling GE (2007) Incorporating historical control data when comparing tumor incidence rates. J Am Stat Assoc 102:1212–1220

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Tarazona JV, Court-Marques D, Tiramani M, Reich H, Pfeil R, Istace F, Crivellente F (2017) Glyphosate toxicity and carcinogenicity: a review of the scientific basis of the European Union assessment and its differences with IARC. Toxicol, Arch. doi:10.1007/s00204-017-1962-5

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Thun, Switzerland

    Christopher J. Portier

  2. PAN Germany, Nernstweg 32, 22765, Hamburg, Germany

    Peter Clausing

Authors
  1. Christopher J. Portier
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Peter Clausing
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Peter Clausing.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Portier, C.J., Clausing, P. Re: Tarazona et al. (2017): Glyphosate toxicity and carcinogenicity: a review of the scientific basis of the European Union assessment and its differences with IARC. doi: 10.1007/s00204-017-1962-5. Arch Toxicol 91, 3195–3197 (2017). https://doi.org/10.1007/s00204-017-2009-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00204-017-2009-7

Search

Navigation