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Open letter to the European commission: scientifically unfounded precaution drives European commission’s recommendations on EDC regulation, while defying common sense, well-established science, and risk assessment principles

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Notes

  1. This letter was provided by Prof. Daniel R. Dietrich. A similar text has been published in ALTEX. 30, 3/13, 381–385 and in Chemico Biological Interactions.

References

  • Birnbaum L (2013) When environmental chemicals act like uncontrolled medicine. Trends Endocrinol Metab doi:10.1016/j.tem.2012.12.005. [Epub ahead of print]

  • Boobis AR, Daston GP, Preston RJ, Olin SS (2009) Application of key events analysis to chemical carcinogens and noncarcinogens. Crit Rev Food Sci Nutr 49(8):690–707

    Article  PubMed  CAS  Google Scholar 

  • Borgert CJ, Sargent EV, Casella G, Dietrich DR, McCarty LS, Golden RJ (2012) The human relevant potency threshold: reducing uncertainty by human calibration of cumulative risk assessments. Regul Toxicol Pharmacol 62(2):313–328

    Article  PubMed  CAS  Google Scholar 

  • European Food Safety Authority Scientific Committee (2013) Scientific opinion on the hazard assessment of endocrine disruptors: scientific criteria for identification of endocrine disruptors and appropriateness of existing test methods for assessing effects mediated by these substances on human health and the environment. EFSA J 11(3):3132–3216

    Google Scholar 

  • Piersma AH, Hernandez LG, van Benthen J, Muller JJA, van Leuween FXR, Vermiere TG, van Raaij MTM (2011) Reproductive toxicants have a threshold of adversity. Crit Rev Toxicol 41(6):545–554

    Article  PubMed  CAS  Google Scholar 

  • Rhomberg LR, Goodman JE (2012) Low-dose effects and nonmonotonic dose–responses of endocrine disrupting chemicals: has the case been made? Regul Toxicol Pharmacol 64:130–133

    Article  PubMed  CAS  Google Scholar 

  • Rhomberg LR, Goodman JE, Haber LH, Dourson M, Andersen ME, Klaunig JE, Meek B, Price PS, McClellan RO, Cohen SM (2011) Linear low-dose extrapolation for noncancer health effects is the exception, not the rule. Crit Rev Toxicol 41(1):1–19

    Article  PubMed  Google Scholar 

  • Sheehan DM (2006) No-threshold dose-response curves for nongenotoxic chemicals: findings and applications for risk assessment. Environ Res 100:93–99

    Article  PubMed  CAS  Google Scholar 

  • Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR Jr, Lee DH, Shioda T, Soto AM, Vom Saal FS, Welshons WV, Zoeller RT, Myers JP (2012) Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev 33(3):378–455

    Article  PubMed  CAS  Google Scholar 

  • Zoeller RT, Brown TR, Doan LL, Gore AC, Skakkebaek NE, Soto AM, Woodruff TJ, Vom Saal FS (2012) Minireview: endocrine-disrupting chemicals and public health protection: a statement of principles from the endocrine society. Endocrinology 153(9):1–14

    Article  Google Scholar 

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Correspondence to Daniel Dietrich.

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The opinions expressed herein are solely those of the authors of this letter, and do not necessarily reflect the positions or views of Springer Science + Business Media.

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Dietrich, D., von Aulock, S., Marquardt, H.W.J. et al. Open letter to the European commission: scientifically unfounded precaution drives European commission’s recommendations on EDC regulation, while defying common sense, well-established science, and risk assessment principles. Arch Toxicol 87, 1739–1741 (2013). https://doi.org/10.1007/s00204-013-1117-2

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  • DOI: https://doi.org/10.1007/s00204-013-1117-2

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