Abstract
We compared safety and efficacy of Gynemesh PS® and Pelvicol® for recurrent cystocele repair. One hundred ninety patients were randomly divided into Gynemesh PS® and Pelvicol® groups and underwent tension-free cystocele repair. The Chi-square test was used to compare categorical variables, the paired t test for continuous parametric variables, and the Mann–Whitney test for continuous nonparametric variables. Ninety-six Gynemesh PS® patients and 94 Pelvicol® patients were studied. Mesh erosions occurred in 6.3% of Gynemesh PS® patients. No erosions were observed in Pelvicol® patients (p = 0.02). Objective cure was 71.9% for Gynemesh PS® and 56.4% for Pelvicol® (p = 0.06). Subjective cure was the same in both groups except for better sexuality in the Pelvicol® group. At 24 months follow-up, only Gynemesh PS® patients had mesh erosions. Anatomical outcome was similar in the two groups. Pelvicol® gave a better impact on voiding and sexuality.
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Abbreviations
- LM:
-
levator myorrhaphy
- POP:
-
pelvic organ prolapse
- POP-Q:
-
pelvic organ prolapse quantification
- PISQ-12:
-
Pelvic Organ Prolapse–Urinary Incontinence Sexual Questionnaire
- TCR:
-
tension-free cystocele repair
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Natale, F., La Penna, C., Padoa, A. et al. A prospective, randomized, controlled study comparing Gynemesh®, a synthetic mesh, and Pelvicol®, a biologic graft, in the surgical treatment of recurrent cystocele. Int Urogynecol J 20, 75–81 (2009). https://doi.org/10.1007/s00192-008-0732-6
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DOI: https://doi.org/10.1007/s00192-008-0732-6