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The role of meniscal tissue in joint protection in early osteoarthritis

  • Knee
  • Published:
Knee Surgery, Sports Traumatology, Arthroscopy Aims and scope

Abstract

It is widely accepted that partial meniscectomy leads to early onset of osteoarthritis (OA). A strong correlation exists between the amount and location of the resected meniscus and the development of degenerative changes in the knee. On the other hand, osteoarthritic changes of the joint alter the structural and functional integrity of meniscal tissue. These alterations might additionally compromise the limited healing capacity of the meniscus. In young, active patients without cartilage damage, meniscus therapy including partial meniscectomy, meniscus suture, and meniscus replacement has proven beneficial effects in long-term studies. Even in an early osteoarthritic milieu, there is a relevant regenerative potential of the meniscus and the surrounding cartilage. This potential should be taken into account, and meniscal surgery can be performed with the correct timing and the proper indication even in the presence of early OA.

Level of evidence IV.

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Author information

Authors and Affiliations

  1. Ghent University, De Pintelaan 185, 9000, Ghent, Belgium

    Rene Verdonk

  2. Department of Orthopaedic Surgery, Saarland University Medical Center, Kirrberger Strasse 100, Building 37-38, 66421, Homburg, Saarland, Germany

    Henning Madry

  3. Department of Radiology, Carmel Medical Center, Haifa, Israel

    Nogah Shabshin

  4. Department of Radiology, Hospital of University of Pennsylvania, Philadelphia, PA, USA

    Nogah Shabshin

  5. Orthopädie und Sportchirurgie, Schloss Puchenau, Karl-Leitl-Str. 1, 4048, Linz-Puchenau, Austria

    Florian Dirisamer

  6. IRCCS Istituto Ortopedico Galeazzi, Milan, Italy

    Giuseppe M. Peretti

  7. Department of Biomedical Sciences for Health, University of Milan, Milan, Italy

    Giuseppe M. Peretti

  8. Centre hospitalier de Versailles, 177, rue de Versailles, 78150, Le Chesnay, France

    Nicolas Pujol

  9. Department of Orthopaedics, University Hospital of Coventry and Warwickshire, Rugby, UK

    Tim Spalding

  10. Antwerp Orthopedic Center, Monica Hospitals, Antwerp, Belgium

    Peter Verdonk

  11. Clinique d’Eich and Sports Medicine Research Laboratory, Department of Orthopaedic Surgery, Centre Hospitalier Luxembourg, Luxembourg Institute of Health, 78 rue d’Eich, 1460, Luxembourg, Luxembourg

    Romain Seil

  12. Dipartimento di Ortopedia - Responsabile di Struttura Semplice di Traumatologia dello, Sport Knee Surgery and Sports Traumatology Ospedale Sacro Cuore - Don Calabria Via Don, Sempreboni, 5, 37024, Negrar Verona, Italy

    Vincenzo Condello

  13. II Orthopaedic Clinic and Biomechanics Lab, Istituto Ortopedico Rizzoli, Bologna, Italy

    Berardo Di Matteo

  14. Department of Trauma Surgery, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93042, Regensburg, Germany

    Johannes Zellner & Peter Angele

  15. Sporthopaedicum Regensburg, Hildegard von Bingen Strasse 1, 93053, Regensburg, Germany

    Peter Angele

Authors
  1. Rene Verdonk
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  2. Henning Madry
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  3. Nogah Shabshin
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  4. Florian Dirisamer
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  5. Giuseppe M. Peretti
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  6. Nicolas Pujol
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  7. Tim Spalding
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  8. Peter Verdonk
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  9. Romain Seil
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  10. Vincenzo Condello
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  11. Berardo Di Matteo
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  12. Johannes Zellner
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  13. Peter Angele
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Corresponding author

Correspondence to Peter Angele.

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Conflict of interest

Some of the authors have relationship with Orteq Sports Medicine, London, UK, and Active Implants, Memphis, USA.

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Verdonk, R., Madry, H., Shabshin, N. et al. The role of meniscal tissue in joint protection in early osteoarthritis. Knee Surg Sports Traumatol Arthrosc 24, 1763–1774 (2016). https://doi.org/10.1007/s00167-016-4069-2

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  • DOI: https://doi.org/10.1007/s00167-016-4069-2

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