Skip to main content

Advertisement

Log in

Periarticular injections with continuous perfusion of local anaesthetics provide better pain relief and better function compared to femoral and sciatic blocks after TKA: a randomized clinical trial

  • Knee
  • Published:
Knee Surgery, Sports Traumatology, Arthroscopy Aims and scope

Abstract

Purpose

Combined femoral and sciatic nerve blocks for post-operative pain management following total knee arthroplasty (TKA) improve patient satisfaction, decrease narcotic consumption and improve pain. However, accompanying motoric weakness can cause falls and related complications. We wonder whether peri-capsular injections in combination with intra-articular perfusion of local anaesthetics would result in equal or less pain without the related complications of nerve blocks. The objective of the study was to verify these aspects in a prospective randomized trial comparing both treatments.

Methods

Fifty TKA patients randomly received either a femoral (continuous) and a sciatic (single-shot) nerve block (CFNB group, 25 knees) or periarticular infiltrations and a continuous post-operative intra-articular infusion (PIAC group, 25 knees). VAS for pain, pain medication consumption, functional assessment, straight leg raising as well as KSS were recorded post-operatively for 6 days.

Results

VAS (p < 0.001) and KSS (p = 0.05) were significantly better for PIAC. There was increased pain following CFNB compared to PIAC. Catheters stayed for 4 days, a pain ‘rebound’ occurred after removing in CFNB but not after PIAC. There was no difference in regard to knee function (n.s.), but straight leg raising was significant better following PIAC. There were two falls in patients with CFNB.

Conclusion

Peri-capsular injections combined with an intra-articular catheter provide better pain control, no rebound pain with better function and might decrease the risk of complications related to motor weakness.

Level of evidence

I.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Affas F, Nygards EB, Stiller CO, Wretenberg P, Olofsson C (2011) Pain control after total knee arthroplasty: a randomized trial comparing local infiltration anesthesia and continuous femoral block. Acta Orthop 82(4):441–447

    Article  PubMed  PubMed Central  Google Scholar 

  2. Ali A, Sundberg M, Hansson U, Malmvik J, Flivik G (2014) Doubtful effect of continuous intraarticular analgesia after total knee arthroplasty. Acta Orthop. doi:10.3109/17453674.2014.991629

    PubMed Central  Google Scholar 

  3. Andersen KV, Bak M, Christensen BV, Harazuk J, Pedersen NA, Soballe K (2010) A randomized, controlled trial comparing local infiltration analgesia with epidural infusion for total knee arthroplasty. Acta Orthop 81(5):606–610

    Article  PubMed  PubMed Central  Google Scholar 

  4. Andersen LO, Kehlet H (2014) Analgesic efficacy of local infiltration analgesia in hip and knee arthroplasty: a systematic review. Br J Anaesth 113(3):360–374

    Article  CAS  PubMed  Google Scholar 

  5. Bianconi M, Ferraro L, Traina GC, Zanoli G, Antonelli T, Guberti A, Ricci R, Massari L (2003) Pharmacokinetics and efficacy of ropivacaine continuous wound instillation after joint replacement surgery. Br J Anaesth 91(6):830–835

    Article  CAS  PubMed  Google Scholar 

  6. Carli F, Clemente A, Asenjo JF, Kim DJ, Mistraletti G, Gomarasca M, Morabito A, Tanzer M (2010) Analgesia and functional outcome after total knee arthroplasty: periarticular infiltration vs continuous femoral nerve block. Br J Anaesth 105(2):185–195

    Article  CAS  PubMed  Google Scholar 

  7. Chaumeron A, Audy D, Drolet P, Lavigne M, Vendittoli PA (2013) Periarticular injection in knee arthroplasty improves quadriceps function. Clin Orthop Relat Res 471(7):2284–2295

    Article  PubMed  PubMed Central  Google Scholar 

  8. Egloff C, Hugle T, Valderrabano V (2012) Biomechanics and pathomechanisms of osteoarthritis. Swiss Med Wkly. doi:10.4414/smw.2012.13583

    PubMed  Google Scholar 

  9. Fu H, Wang J, Zhang W, Cheng T, Zhang X (2015) Potential superiority of periarticular injection in analgesic effect and early mobilization ability over femoral nerve block following total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. doi:10.1007/s00167-015-3519-6

    Google Scholar 

  10. Goyal N, McKenzie J, Sharkey PF, Parvizi J, Hozack WJ, Austin MS (2013) The 2012 Chitranjan Ranawat award: intraarticular analgesia after TKA reduces pain: a randomized, double-blinded, placebo-controlled, prospective study. Clin Orthop Relat Res 471(1):64–75

    Article  PubMed  Google Scholar 

  11. Hadzic A, Houle TT, Capdevila X, Ilfeld BM (2010) Femoral nerve block for analgesia in patients having knee arthroplasty. Anesthesiology 113(5):1014–1015

    Article  PubMed  Google Scholar 

  12. Kim TW, Park SJ, Lim SH, Seong SC, Lee S, Lee MC (2015) Which analgesic mixture is appropriate for periarticular injection after total knee arthroplasty? Prospective, randomized, double-blind study. Knee Surg Sports Traumatol Arthrosc 23(3):838–845

    Article  PubMed  Google Scholar 

  13. Korean Knee S (2012) Guidelines for the management of postoperative pain after total knee arthroplasty. Knee Surg Relat Res 24(4):201–207

    Article  Google Scholar 

  14. Marhofer P, Harrop-Griffiths W, Kettner SC, Kirchmair L (2010) Fifteen years of ultrasound guidance in regional anaesthesia: part 1. Br J Anaesth 104(5):538–546

    Article  CAS  PubMed  Google Scholar 

  15. Marhofer P, Harrop-Griffiths W, Willschke H, Kirchmair L (2010) Fifteen years of ultrasound guidance in regional anaesthesia: part 2-recent developments in block techniques. Br J Anaesth 104(6):673–683

    Article  CAS  PubMed  Google Scholar 

  16. McCartney CJ, McLeod GA (2011) Local infiltration analgesia for total knee arthroplasty. Br J Anaesth 107(4):487–489

    Article  CAS  PubMed  Google Scholar 

  17. Michael JW, Schluter-Brust KU, Eysel P (2010) The epidemiology, etiology, diagnosis, and treatment of osteoarthritis of the knee. Dtsch Arztebl Int 107(9):152–162

    PubMed  PubMed Central  Google Scholar 

  18. Moghtadaei M, Farahini H, Faiz SH, Mokarami F, Safari S (2014) Pain management for total knee arthroplasty: single-injection femoral nerve block versus local infiltration analgesia. Iran Red Crescent Med J 16(1):e13247

    Article  PubMed  PubMed Central  Google Scholar 

  19. Nakai T, Tamaki M, Nakamura T, Nakai T, Onishi A, Hashimoto K (2013) Controlling pain after total knee arthroplasty using a multimodal protocol with local periarticular injections. J Orthop 10(2):92–94

    Article  PubMed  PubMed Central  Google Scholar 

  20. Niemelainen M, Kalliovalkama J, Aho AJ, Moilanen T, Eskelinen A (2014) Single periarticular local infiltration analgesia reduces opiate consumption until 48 hours after total knee arthroplasty. A randomized placebo-controlled trial involving 56 patients. Acta Orthop 85(6):614–619

    Article  PubMed  PubMed Central  Google Scholar 

  21. Ong JC, Chin PL, Fook-Chong SM, Tang A, Yang KY, Tay BK (2010) Continuous infiltration of local anaesthetic following total knee arthroplasty. J Orthop Surg (Hong Kong) 18(2):203–207

    Article  Google Scholar 

  22. Paul JE, Arya A, Hurlburt L, Cheng J, Thabane L, Tidy A, Murthy Y (2010) Femoral nerve block improves analgesia outcomes after total knee arthroplasty: a meta-analysis of randomized controlled trials. Anesthesiology 113(5):1144–1162

    Article  PubMed  Google Scholar 

  23. Reinhardt KR, Duggal S, Umunna BP, Reinhardt GA, Nam D, Alexiades M, Cornell CN (2014) Intraarticular analgesia versus epidural plus femoral nerve block after TKA: a randomized, double-blind trial. Clin Orthop Relat Res 472(5):1400–1408

    Article  PubMed  Google Scholar 

  24. Sharma S, Iorio R, Specht LM, Davies-Lepie S, Healy WL (2010) Complications of femoral nerve block for total knee arthroplasty. Clin Orthop Relat Res 468(1):135–140

    Article  PubMed  Google Scholar 

  25. Spangehl MJ, Clarke HD, Hentz JG, Misra L, Blocher JL, Seamans DP (2015) The Chitranjan Ranawat Award: periarticular injections and femoral & sciatic blocks provide similar pain relief after TKA: a randomized clinical trial. Clin Orthop Relat Res 473(1):45–53

    Article  PubMed  Google Scholar 

  26. Szucs S, Morau D, Iohom G (2010) Femoral nerve blockade. Med Ultrason 12(2):139–144

    PubMed  Google Scholar 

  27. Teng Y, Jiang J, Chen S, Zhao L, Cui Z, Khan MS, Du W, Gao X, Wang J, Xia Y (2014) Periarticular multimodal drug injection in total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 22(8):1949–1957

    Article  PubMed  Google Scholar 

  28. Toftdahl K, Nikolajsen L, Haraldsted V, Madsen F, Tonnesen EK, Soballe K (2007) Comparison of peri- and intraarticular analgesia with femoral nerve block after total knee arthroplasty: a randomized clinical trial. Acta Orthop 78(2):172–179

    Article  PubMed  Google Scholar 

  29. Uesugi K, Kitano N, Kikuchi T, Sekiguchi M, Konno S (2014) Comparison of peripheral nerve block with periarticular injection analgesia after total knee arthroplasty: a randomized, controlled study. Knee 21(4):848–852

    Article  PubMed  Google Scholar 

  30. Van Manen MD, Nace J, Mont MA (2012) Management of primary knee osteoarthritis and indications for total knee arthroplasty for general practitioners. J Am Osteopath Assoc 112(11):709–715

    PubMed  Google Scholar 

  31. Yadeau JT, Goytizolo EA, Padgett DE, Liu SS, Mayman DJ, Ranawat AS, Rade MC, Westrich GH (2013) Analgesia after total knee replacement: local infiltration versus epidural combined with a femoral nerve blockade: a prospective, randomised pragmatic trial. Bone Joint J 95-B(5):629–635

    Article  CAS  PubMed  Google Scholar 

  32. Yuenyongviwat V, Pornrattanamaneewong C, Chinachoti T, Chareancholvanich K (2012) Periarticular injection with bupivacaine for postoperative pain control in total knee replacement: a prospective randomized double-blind controlled trial. Adv Orthop 2012:107309

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to J. Beckmann.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Stathellis, A., Fitz, W., Schnurr, C. et al. Periarticular injections with continuous perfusion of local anaesthetics provide better pain relief and better function compared to femoral and sciatic blocks after TKA: a randomized clinical trial. Knee Surg Sports Traumatol Arthrosc 25, 2702–2707 (2017). https://doi.org/10.1007/s00167-015-3633-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00167-015-3633-5

Keywords

Navigation