Abstract
Objective
To determine the reliability of whole-body impedance cardiography (ICGWB), with electrodes attached to wrists and ankles, in the measurement of cardiac output (CO) on the basis of simultaneous comparison with thermodilution (TD) and direct oxygen Fick (Fick) methods.
Design
Prospective clinical study.
Setting
A surgical intensive care unit at a university hospital.
Patients
Thirty consecutive subjects undergoing a coronary artery bypass surgery were investigated preoperatively.
Measurements
ICGWB derived CO was measured simultaneously with the TD and Fick methods to establish the biases and limits of agreement (LA) between the methods.
Results
The results obtained by ICGWB and the invasive methods showed good agreement. The bias and LA between COTD and COICG were 0.001/min; −1.37 and 1.37 1/min, respectively, and were close to those obtained between COTD and COFICK, 0.321/min; 1.74 and −1.101/ min. The bias and LA between the COFICK and COICG were −0.32 1/min; −2.24 and 1.60 1/min respectively. The repeatability value of consecutive single measurements for ICGWB (RVICG=0.571/min) was much better than for the TD method (RVTD=1.10 1/min).
Conclusion
There was close agreement between the results of the three methods in the measurement of CO. In sedated preoperative patients the accuracy of ICGWB is within clinically acceptable limits and its repeatability is excellent. ICGWB provides a useful alternative to the TD and Fick methods in cases where the pressures supplied by the pulmonary artery catheter are not essential.
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References
Kubicek WG, Karnegis JN, Patterson RP, Witsoe DA, Mattson RH (1966) Development and evaluation of an impedance cardiac output system. Aerospace Med 37:1208–1212
Sramek BB (1989) Hemodynamic and pump-performance monitoring by electrical bioimpedance. New concepts. Probi Respir Care 2: 274–290
Bernstein DP (1986) A new stroke volume equation for thoracic electrical bioimpedance: theory and rationale. Crit Care Med 14: 904–909
Fuller HD (1992) The validity of cardiac output measurement by thoracic impedance: a meta-analysis. Clin Invest Med 15:103–112
Horstmann E, Konn B (1993–94) Assessment of cardiac output during exercise. Transthoracic impedance vs. heart rate alone. Med Prog Technol 19: 173–178
Bishop MH, Shoemaker WC, Shuleshko J, Wo CCJ (1996) Noninvasive cardiac index monitoring in gunshot wound victims. Acad Emerg Med 3: 682–688
Atallah MM, Demain AD (1995) Cardiac output measurement: lack of agreement between thermodilution and thoracic electric bioimpedance in two clinical settings. J Clin Anesth 7:182–185
De-Mey C, Enterling D (1993) Disagreement between standard transthoracic impedance cardiography and the automated transthoracic electrical bioimpedance method in estimating the cardiovascular responses to phenylephrine and isoprenaline in healthy man. Br J Clin Pharmacol 35: 349–355
Belardinelli R, Ciampani N, Costantini C, Blandini A, Purcaro A (1996) Comparison of impedance cardiography with thermodilution and direct Fick methods for noninvasive measurement of stroke volume and cardiac output during incremental exercise in patients with ischemic cardiomyopathy. Am J Cardiol 77:1293–1301
Milsom I, Sivertsson R, Biber B, Olsson T (1982) Measurement of stroke volume with impedance cardiography. Clin Physiol 2: 409–417
Sundberg S, Akkila J (1996) Assessment of cardiac performance: Short-and medium-term variability of impedance cardiography at rest and during dynamic exercise. Int J Clin Pharmacol Ther 34: 93–95
Tishchenko MI (1973) Estimation of the stroke volume by integral rheogram of the human body. Sechenov Physiol J 59:1216–1224
Lamberts R, Visser KR, Zijlstra WG (1984) Impedance cardiography. Van Gorcum, Assen, The Netherlands, pp 65–70
Kööbi T, Kaukinen S, Turjanmaa VMH, Uusitalo AJ (1997) Whole-body impedance cardiography in the measurement of cardiac output. Crit Care Med 25: 779–785
Tishchenko MI, Smirnov AD, Danilov LN, Aleksandrov AL (1973) Characteristics and clinical use of integral rheography — a new method of measuring the stroke volume. Kardiologiia 13: 54–62
Golikov AP, Berestov AA, Maiorov NI, Riabinin VA (1977) Experience in using integral rheography for evaluating the hemodynamic indices in emergency states in cardiology. Kardiologiia 17: 54–58
Mackenzie JD, Haites NE, Rawles JM (1986) Method of assessing the reproducibility of blood flow measurement: factors influencing the performance of thermodilution cardiac output computers. Br Heart J 55:14–24
Saksena FB (1983) Hemodynamics in Cardiology. Praeger Publishers, New York, pp 3–12
Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1: 307–310
British Standards Institution (1987) Precision of test methods — Determination of repeatability and reproducibility for a standard test method by inter-laboratory tests. (BS 5497: Part 1), London, British Standard Institution, pp 3–8
Hillis LD, Firth BG, Winniford MD (1985) Analysis of factors affecting the variability of Fick versus indicator dilution measurements of cardiac output. Am J Cardiol 56: 764–768
Mahutte CK, Jaffe MB, Chen PA, Sasse SA, Wong DH, Sassoon CS (1994) Oxygen Fick and modified carbon dioxide Fick cardiac outputs. Crit Care Med 22: 86–95
Levett JM, Replogle RL (1979) Thermodilution cardiac output: a critical analysis and review of the literature. J Surg Res 27: 392–404
Stetz CW, Miller RG, Kelly GE, Raffin TA (1982) Reliability of the thermodilution method in the determination of cardiac output in clinical practice. Am Rev Respir Dis 126:1001–1004
Johnson RW, Normann RA (1988) Signal processing strategies for enhancement of signal-to-noise ratio of thermodilution measurements. Ann Biomed Eng 16: 265–278
Renner LE, Morton MJ, Sakuma GY (1993) Indicator amount, temperature, and intrinsic cardiac output affect thermodilution cardiac output accuracy and reproducibility. Crit Care Med 21: 586–597
Nishikawa T, Dohi S (1993) Errors in the measurement of cardiac output by thermodilution. Can J Anaesth 40:142–153
Jansen JR (1995) The thermodilution method for the clinical assessment of cardiac output. Intensive Care Med 21: 691–697
Stevens JH, Raffin TA, Mihm FG, Rosenthal MH, Stetz CW (1985) Thermodilution cardiac output measurement. Effects of the respiratory cycle on its reproducibility. JAMA 253: 2240–2242
Jansen JR, Versprille A (1986) Improvement of cardiac output estimation by the thermodilution method during mechanical ventilation. Intensive Care Med 12: 71–79
Powner DJ, Snyder JV (1978) In vitro comparison of six commercially available thermodilution cardiac output systems. Med Instruments 12:122–127
Rubini A, Del-Monte D, Catena V, Attar I, Cesaro M, Soranzo D, Rattazzi G, Alati GL (1995) Cardiac output measurement by the thermodilution method: an in vitro test of accuracy of three commercially available automatic cardiac output computers. Intensive Care Med 21:154–158
Russell AE, Smith SA, West MJ, Aylward PE, McRitchie RJ, Hassam RM, Minson RB, Wing LM, Chalmers JP (1990) Automated non-invasive measurement of cardiac output by the carbon dioxide rebreathing method: comparisons with dye dilution and thermodilution. Br Heart J 63:195–199
Espersen K, Jensen EW, Rosenborg D, Thomsen JK, Eliasen K, Olsen NV, Kanstrup IL (1995) Comparison of cardiac output measurement techniques: thermodilution, Doppler, CO2-rebreathing and the direct Fick method. Acta Anaesthesiol Scand 39: 245–251
Axler O, Tousignant C, Thompson CR, DallavaSantucci J, Phang PT, Russell JA, Walley KR (1996) Comparison of transesophageal echocardiographic, Fick, and thermodilution cardiac output in critically ill patients. J Crit Care 11: 109–116
Mahutte CK, Jaffe MB (1995) Effect of measurement errors on cardiac output calculated with O2 and modified CO2 Fick methods. J Clin Monit 11: 99–108
Sasse SA, Chen PA, Berry RB, Sassoon CS, Mahutte CK (1994) Variability of cardiac output over time in medical intensive care unit patients. Crit Care Med 22: 225–232
Elkayam U, Berkley R, Azen S, Weber L, Geva B, Henry WL (1983) Cardiac output by thermodilution technique. Effect of injectate’s volume and temperature on accuracy and reproducibility in the critically ill patient. Chest 84: 418–422
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This study was supported by the Medical Research Fund of Tampere University Hospital
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Kööbi, T., Kaukinen, S., Ahola, T. et al. Non-invasive measurement of cardiac output: whole-body impedance cardiography in simultaneous comparison with thermodilution and direct oxygen Fick methods. Intensive Care Med 23, 1132–1137 (1997). https://doi.org/10.1007/s001340050469
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DOI: https://doi.org/10.1007/s001340050469