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Entwicklung der pulsatilen GnRH-Therapie

Development of pulsatile GnRH administration

  • Geschichte der Gynäkologie und Geburtshilfe
  • Published:
Der Gynäkologe Aims and scope

Zusammenfassung

Die Entwicklung der pulsatilen GnRH-Therapie durch Leyendecker hat die Behandlung der Sterilität bei der schweren hypothalamischen Amenorrhö revolutioniert und war eine der wichtigsten Erfolge der deutschen Endokrinologie in den 1970er- und -80er-Jahren. Sie gilt heute als ein herausragendes Beispiel der Umsetzung neuester physiologischer Erkenntnisse in die Beurteilung und Behandlung eines schweren endokrinen Krankheitsbildes.

Abstract

The development of pulsatile GnRH administration has deeply influenced the treatment of severe hypothalamic amenorrhea and is considered as one of the most important achievements of German endocrinology during the 1970s and early 1980s. Pulsatile GnRH administration is an outstanding example of translating physiological knowledge into the evaluation and treatment of a severe endocrine disorder.

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  1. Gynäkologische Endokrinologie und Fertilitätsstörungen, Universitäts-Frauenklinik, Voßstr. 9, 69115, Heidelberg, Deutschland

    T. Strowitzki

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Strowitzki, T. Entwicklung der pulsatilen GnRH-Therapie. Gynäkologe 44, 1009–1014 (2011). https://doi.org/10.1007/s00129-011-2883-7

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