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Hepatic Enzymes Activity in the Fish Prochilodus Lineatus (Valenciennes, 1836) After Sublethal Cypermethrin Exposure

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Abstract

Prochilodus lineatus, a fish, was exposed to sublethal concentrations of cypermethrin: 0.075, 0.150, and 0.300 μg L−1 and a control group (without cypermethrin) for 96 h. Five specimens were exposed in each concentration for triplicate (n = 60). Hepatic biochemical values and behavioral changes were studied. The results revealed a significantly higher level of aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase in hepatic tissue at different concentrations of cypermethrin tested compared to control (p < 0.05). A decrease in total protein was observed in exposed groups but not significantly (p > 0.05). This study provides information to know toxic mechanisms of cypermethrin on hepatic enzymes of P. lineatus that are poorly understood.

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Acknowledgments

The work was supported by research grant PI CAI + D 21/123-2006 from Universidad Nacional del Litoral, Argentina. The authors are especially grateful to Dra. Gisela L. Poletta and Bioq. Ana C. Lorenzi, who provided expert help during the research.

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Authors and Affiliations

  1. Cátedra de Toxicología y Bioquímica Legal, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Ciudad Universitaria, Paraje El Pozo C.C 242 (3000), Santa Fe, Argentina

    A. Loteste, J. Scagnetti & M. F. Simoniello

  2. Instituto Nacional de Limnología (INALI), CONICET-UNL, Ciudad Universitaria, Paraje El Pozo C.C 242 (3000), Santa Fe, Argentina

    A. Loteste, M. Campana & M. J. Parma

  3. Facultad de Humanidades y Ciencias, Universidad Nacional del Litoral, Ciudad Universitaria, Paraje El Pozo C.C 242 (3000), Santa Fe, Argentina

    M. J. Parma

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  1. A. Loteste
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  2. J. Scagnetti
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  3. M. F. Simoniello
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  4. M. Campana
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  5. M. J. Parma
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Correspondence to M. J. Parma.

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Loteste, A., Scagnetti, J., Simoniello, M.F. et al. Hepatic Enzymes Activity in the Fish Prochilodus Lineatus (Valenciennes, 1836) After Sublethal Cypermethrin Exposure. Bull Environ Contam Toxicol 90, 601–604 (2013). https://doi.org/10.1007/s00128-013-0961-3

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  • DOI: https://doi.org/10.1007/s00128-013-0961-3

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