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Peniskarzinom

Diagnose und Therapie

Penile carcinoma

Diagnosis and therapy

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Zusammenfassung

Das Peniskarzinom ist glücklicherweise eine relativ seltene Erkrankung in Mitteleuropa, denn fortgeschrittene Tumorstadien sind nicht heilbar. Aber diese Seltenheit bedingt auch Nachteile für die Betroffenen: Daten größerer Serien als Evidenzgrundlage sind selten, Leitlinien in ihren Formulierungen oft entsprechend vage und Forschungsmittel für Therapiestudien rar. Das Peniskarzinom ist eine „orphan disease“. Trotz dieser nachteiligen Besonderheiten haben insbesondere auch Forschungen zu den molekularbiologischen Grundlagen des Peniskarzinoms in den letzten Jahren einige Fortschritte ermöglicht. Dieser Artikel gibt eine aktuelle Übersicht zu allen relevanten Aspekten dieser Erkrankung.

Abstract

Penile carcinoma is fortunately a relatively rare disease in central Europe because advanced tumor stages are incurable. However, this rarity results in disadvantages for those affected because data from large series as an evidence basis are rare, the formulation of guidelines is often correspondingly vague and research funding for therapy studies is limited. Penile carcinoma is an orphan disease. Despite these disadvantageous characteristics research on the molecular biological basis of penile carcinoma has made some progress in recent years. This article gives a current review of all relevant aspects of this disease.

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Authors and Affiliations

  1. Urologische Klinik und Poliklinik, Universitätsklinikum Rostock, Ernst-Heydemann-Str. 6, 18055, Rostock, Deutschland

    C. Protzel & O.W. Hakenberg

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  1. C. Protzel
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  2. O.W. Hakenberg
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Correspondence to C. Protzel.

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Protzel, C., Hakenberg, O. Peniskarzinom. Urologe 52, 87–98 (2013). https://doi.org/10.1007/s00120-012-3004-5

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