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Mandible shape in hybrid mice

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Abstract

Hybridisation between closely related species is frequently seen as retarding evolutionary divergence and can also promote it by creating novel phenotypes due to new genetic combinations and developmental interactions. We therefore investigated how hybridisation affects the shape of the mouse mandible, a well-known feature in evo–devo studies. Parental groups corresponded to two strains of the European mouse sub-species Mus musculus domesticus and Mus musculus musculus. Parents and hybrids were bred in controlled conditions. The mandibles of F1 hybrids are mostly intermediate between parental phenotypes as expected for a complex multigenic character. Nevertheless, a transgressive effect as well as an increased phenotypic variance characterise the hybrids. This suggests that hybridisation between the two subspecies could lead to a higher phenotypic variance due to complex interactions among the parental genomes including non-additive genetic effects. The major direction of variance is conserved, however, among hybrids and parent groups. Hybridisation may thus play a role in the production of original transgressive phenotypes occurring following pre-existing patterns of variance.

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Acknowledgements

We would like to thank F. Fel-Clair, K. Manolakou, A. Orth and A. Zaegek for help and technical assistance during the rearing of the animals. We also thank the GDR 2474 CNRS “Morphométrie et Evolution des Formes” for financial support in the last steps of the work. This is contribution ISEM 2009-059.

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Authors and Affiliations

  1. Paléoenvironnement et Paléobiosphère, UMR 5125 CNRS, Université Lyon 1, Bâtiment Géode, 2 rue Dubois, Campus de la Doua, 69622, Villeurbanne cedex, France

    Sabrina Renaud

  2. Biogéosciences, UMR 5561 CNRS, Université de Bourgogne, bâtiment Gabriel, 21000, Dijon, France

    Paul Alibert

  3. Institut des Sciences de l’Evolution, UMR 5554 CNRS, Université Montpellier 2, 34095, Montpellier, France

    Jean-Christophe Auffray

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  1. Sabrina Renaud
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  2. Paul Alibert
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  3. Jean-Christophe Auffray
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Correspondence to Sabrina Renaud.

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Renaud, S., Alibert, P. & Auffray, JC. Mandible shape in hybrid mice. Naturwissenschaften 96, 1043–1050 (2009). https://doi.org/10.1007/s00114-009-0563-4

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  • DOI: https://doi.org/10.1007/s00114-009-0563-4

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