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Genetics of the human renin angiotensin system

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Abstract

The genes coding for the renin angiotensin system have been extensively studied. During the last 15 years, informative markers and functional polymorphisms have been identified, and numerous linkage and association studies have been performed in cardiovascular diseases, especially human hypertension. This mini-review aims to summarize the main findings observed for each component of this enzymatic cascade taken alone or in combination, with an emphasis on the most recent or innovative studies.

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Authors and Affiliations

  1. INSERM U772, Collège de France, 11 place Marcelin Berthelot, 75005, Paris, France

    Xavier Jeunemaitre

  2. Hôpital Européen Georges Pompidou, Paris, France

    Xavier Jeunemaitre

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  1. Xavier Jeunemaitre
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Correspondence to Xavier Jeunemaitre.

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Jeunemaitre, X. Genetics of the human renin angiotensin system. J Mol Med 86, 637–641 (2008). https://doi.org/10.1007/s00109-008-0344-0

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  • DOI: https://doi.org/10.1007/s00109-008-0344-0

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