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Hidradenitis suppurativa/Acne inversa in der Genitoanalregion

Hidradenitis suppurativa/acne inversa in the genitoanal region

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Zusammenfassung

Die Hidradenitis suppurativa/Acne inversa (HS/AI) ist eine chronisch rezidivierende inflammatorische Hauterkrankung. Erhebungen zeigen, dass bevorzugt Männer einen perianalen, perinealen und glutealen Befall aufweisen, wohingegen bei Frauen die Axillen sowie die submammäre und inguinale Region vermehrt betroffen sind. Der Befall der Genitoanalregion ist mit einer stärkeren Einschränkung der Lebensqualität und einer größeren Belastung der sexuellen Gesundheit assoziiert als andere Lokalisationen. Darüber hinaus kann die HS/AI in der Genitoanalregion zu schwerwiegenden Komplikationen führen. Die perianale Fistelbildung, das pubogenitale Lymphödem und das Plattenepithelkarzinom zählen zu den 3 schwersten Komplikationen, deren Kenntnis entscheidend für ein adäquates Therapiemanagement ist.

Abstract

Hidradenitis suppurativa/acne inversa (HS/AI) is a chronic inflammatory skin disease. Several studies showed that perianal, perineal and gluteal involvement is more common in men. Axillary, submammary and inguinal localizations seem to be more prevalent in women. Involvement of the genitoanal region is associated with a higher reduced quality of live and sexual health compared to other locations. Moreover HS/AI in the genitoanal region can lead to serious complications. The knowledge of perianal fistula formation, pubogenital lymphedema and squamous cell carcinoma, which are three of the most severe complications, is critical for adequate treatment.

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Authors and Affiliations

  1. Klinik für Dermatologie und Phlebologie, Katharinen-Hospital Unna, Unna, Deutschland

    S. Hessam

  2. Klinik für Dermatologie, Venerologie und Allergologie, St. Josef-Hospital, Klinik der Ruhr-Universität Bochum, Gudrunstr. 56, 44791, Bochum, Deutschland

    S. Hessam &  F. G. Bechara

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  2. F. G. Bechara
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Correspondence to F. G. Bechara.

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Interessenkonflikt

S. Hessam hat als stellvertretender Studienleiter von der Firma AbbVie gesponserte Phase-III- und -IV-Studien betreut und als Vortragender finanzielle Zuwendung sowie Reisekostenunterstützung erhalten. F.G. Bechara hat als Vortragender und Studienleiter finanzielle Zuwendungen sowie Reisekostenunterstützung von der Firma AbbVie erhalten.

Für diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. Für Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, über die Patienten zu identifizieren sind, liegt von ihnen und/oder ihren gesetzlichen Vertretern eine schriftliche Einwilligung vor.

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Hessam, S., Bechara, F.G. Hidradenitis suppurativa/Acne inversa in der Genitoanalregion. Hautarzt 71, 256–262 (2020). https://doi.org/10.1007/s00105-020-04556-9

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