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Stereotaktische Strahlentherapie von Lebermetastasen

Stereotactic radiation therapy for liver metastases

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Zusammenfassung

Durch die Fortentwicklung strahlentherapeutischer Techniken ist auch ein lokal kurativer Therapieansatz durch eine stereotaktische Bestrahlung einzelner Lebermetastasen möglich. Ergebnisse dieser fokussierten und mit nur wenigen Bestrahlungen durchgeführten Behandlung sind bisher nur von wenigen Zentren publiziert worden. Es zeigt sich übereinstimmend, dass eine hohe lokale Tumorkontrolle bei geringer Morbidität erzielt werden kann. Die bisherigen Erfahrungen zeigen mit dieser nichtinvasiven Technik ähnliche Therapieergebnisse wie nach minimal-invasiven ablativen Therapieverfahren. Die publizierten und die eigenen Daten werden zusammengefasst und diskutiert. Die langfristigen Therapieergebnisse werden derzeit durch eine prospektive multizentrische Studie evaluiert.

Abstract

Advances in radiation oncology made possible the locally curative treatment approach of stereotactically guided radiation therapy of liver tumours. Results of this highly focussed therapy were published by only a few centres. The radiation dose is delivered in one or a few fractions with high single doses. All published results show high local tumour control with low treatment morbidity. The treatment results of this noninvasive technique are similar to those of minimally invasive ablative therapies. Our own and other published data are summarized and discussed. The long-term results of this technique are currently being evaluated in a prospective multicentre trial.

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Authors and Affiliations

  1. Abteilung Radioonkologie und Strahlentherapie, Universitätsklinik Heidelberg

    K. K. Herfarth & J. Debus

  2. Abteilung Radioonkologie und Strahlentherapie, Universitätsklinik Heidelberg, INF 400, 69120 , Heidelberg

    K. K. Herfarth

Authors
  1. K. K. Herfarth
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  2. J. Debus
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Correspondence to K. K. Herfarth.

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Herfarth, K.K., Debus, J. Stereotaktische Strahlentherapie von Lebermetastasen. Chirurg 76, 564–569 (2005). https://doi.org/10.1007/s00104-005-1039-5

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  • DOI: https://doi.org/10.1007/s00104-005-1039-5

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