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Ewing’s sarcoma of the larynx

Effective treatment with organ preservation

Ewing Sarkom des Kehlkopfs

Erfolgreiche Behandlung mit Organerhalt

  • Case study
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Strahlentherapie und Onkologie Aims and scope Submit manuscript

Abstract

Extraskeletal Ewing’s sarcoma arising in the head and neck region is an extremely rare malignant neoplasm. We describe the unusual case of a tumor originating in the larynx of a 68-year-old male with hoarseness and occasional aphonia. We report successful treatment with sequential chemo- and radiotherapy. Complete regression and larynx preservation with voice function recovery was achieved. To our knowledge, this is the first report of this type of tumor in the larynx with cartilage invasion that documents the effectiveness of radiotherapy as an alternative to surgical management. At present, after 30 months of follow-up, the patient is free of tumor relapse and in very good condition.

Zusammenfassung

Das im Kopf- und Halsbereich entstehende Weichteil-Ewing-Sarkom stellt ein äußerst seltenes malignes Neoplasma dar. Wir beschreiben hier einen ungewöhnlichen Fall vom Tumor, der bei einem 68-jährigen Mann mit Heiserkeit und zeitweise auftretender Aphonie entstand. Wir berichten über die erfolgreiche Behandlung mit sequentieller Chemo- und Strahlentherapie. Es wurde eine vollständige Regression erreicht sowie die Kehlkopferhaltung bei Besserung der Stimmfunktion. Nach unserem Wissen ist dies der erste Bericht dieser Tumorart im Kehlkopf mit Knorpelinvasion, der die Wirksamkeit der Strahlentherapie als Alternative zur chirurgischen Behandlung dokumentiert. Nach der 30 Monate dauernden Nachsorge ist der Patient derzeit ohne Tumorrezidiv und in sehr gutem Zustand.

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Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

All authors have nothing to disclose (no conflict of interest).

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Authors and Affiliations

  1. Department of Radiation and Clinical Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Ul. Wybrzeże Armii Krajowej 15, 44-101, Gliwice, Poland

    A. Wygoda M.D., Ph.D., T. Rutkowski M.D., Ph.D. & K. Składowski M.D., Ph.D.

  2. Department of Pathology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland

    D. Ponikiewska M.D

  3. Department of Radiology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland

    B. Hejduk M.D.

Authors
  1. A. Wygoda M.D., Ph.D.
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  2. T. Rutkowski M.D., Ph.D.
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  3. D. Ponikiewska M.D
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  4. B. Hejduk M.D.
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  5. K. Składowski M.D., Ph.D.
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Corresponding author

Correspondence to A. Wygoda M.D., Ph.D..

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I have the consent of the Head of Clinic, Professor Krzysztof Składowski (coauthor), to submit this manuscript to“Strahlentherapie und Onkologie”.

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Wygoda, A., Rutkowski, T., Ponikiewska, D. et al. Ewing’s sarcoma of the larynx. Strahlenther Onkol 189, 586–589 (2013). https://doi.org/10.1007/s00066-013-0356-8

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  • DOI: https://doi.org/10.1007/s00066-013-0356-8

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