Zusammenfassung
Hintergrund
Analabszesse sind relativ häufig und treten bevorzugt bei jungen männlichen Erwachsenen auf.
Methode
Es wurde ein systematisches Review der Literatur vorgenommen.
Ergebnisse
Den Ursprung des Abszesses bilden i. d. R. die Proktodealdrüsen des Intersphinkterraumes. Es wird zwischen subanodermalen, intersphinkteren, ischioanalen und supralevatorischen Abszessen unterschieden. In der Diagnostik sind die Anamnese und die klinische Untersuchung für die Operationsindikation als ausreichend anzusehen. Weiterführende Untersuchungen (Endosonographie, Magnetresonanztomographie) sollten bei Rezidivabszessen oder supralevatorischen Abszessen erwogen werden. Der Zeitpunkt der operativen Intervention wird v. a. durch die Symptomatik bestimmt, wobei der akute Abszess grundsätzlich eine Notfallindikation darstellt. Die Therapie des Analabszesses erfolgt operativ, wobei die Wahl des Zugangs (transrektal oder perianal) von der Abszesslokalisation abhängt. Ziel der Operation ist eine großzügige Drainage des Infektionsherdes unter Schonung der Schließmuskelstrukturen. Die Wunde sollte regelmäßig gespült werden (Ausduschen mit Leitungswasser). Die Anwendung von lokalen Antiseptika birgt die Gefahr der Zytotoxizität. Eine Antibiotikatherapie ist nur in Ausnahmefällen erforderlich. Eine intraoperative Fistelsuche sollte allenfalls sehr vorsichtig erfolgen, ein Fistelnachweis nicht erzwungen werden. Das Risiko einer Re-Abszedierung oder sekundären Fistelbildung ist insgesamt gering; die Ursache kann in einer unzureichenden Drainage bestehen. Eine primäre Fistelspaltung soll nur bei oberflächlichen Fisteln durch einen erfahrenen Operateur erfolgen. Bei unklaren Befunden oder hohen Fisteln soll die Sanierung in einem Zweiteingriff erfolgen.
Schlussfolgerung
In diesen klinischen S3-Leitlinien werden erstmals in Deutschland Richtlinien für die Diagnostik und Therapie des anorektalen Abszesses vorgestellt.
Abstract
Background
Anal abscesses are relatively frequent and most common in young men.
Methods
A systematic review of the literature has been undertaken.
Results
The origin of the abscess is usually the proctodeal gland in the intersphincteric space. There are different types of abscesses: intersphincteric, ischioanal and supralevatory abscesses. Anamnesis and clinical examination are sufficient to indicate surgery. Further examinations such as endosonography or magnetic resonance tomography (MRT) should be considered in recurrent or supralevatory abscesses. The timing of surgical intervention depends on clinical symptoms, whereas the acute abscess is an emergency indication. Surgery is the primary therapy approach for anal abscess. Surgical access (transrectal or perianal) depends on the localization of the abscess. The aim of surgery is to broadly drain the infection and protect anal sphincter structures. The wound should be rinsed regularly (showering with clear water). Treatment with local antiseptics carries the risk of zytotoxicity. Antibiotic treatment is necessary only in selected cases. Any attempt to locate a fistula intraoperatively should be undertaken with great care; proven evidence of a fistula is not mandatory. Although the risk of recurrent abscess or secondary fistula is low, these may be caused by insufficient drainage. The primary fistulotomy of superficial fistulas should only be performed by an experienced surgeon. In the case of ambiguous findings or high fistulas, treatment should be carried out in a second surgical procedure.
Conclusion
For the first time in Germany, this clinical S3 guideline provides instructions for the diagnosis and treatment of anal abscesses based on a systematic review of the literature.
Literatur
Abcarian H (1976) Acute suppurations of the anorectum. Surg Annu 8:305–333
Abcarian H, Dodi G, Girona J et al (1987) Fistula-in-ano. Int J Colorectal Dis 2:51–71
Abeysuriya V, Salgado LS, Samarasekera DN (2010) The distribution of the anal glands and the variable regional occurrence of fistula-in-ano: is there a relationship? Tech Coloproctol 14:317–321
Aboulian A, Kaji AH, Kumar RR (2011) Early result of ligation of the intersphincteric fistula tract for fistula-in-ano. Dis Colon Rectum 54:289–292
Albright JB, Pidala MJ, Cali JR et al (2007) MRSA-related perianal abscesses: an underrecognized disease entity. Dis Colon Rectum
Alyoune M, Nadir S, Merzouk M et al (1994) Tuberculous anal fistulas. 13 cases. Ann Gastroenterol Hepatol (Paris) 30:9–11
Athanasiadis S, Fischbach N, Heumuller L, Marla B (1990) Abscessexcision und primare Fistulektomie als Initialtherapie des periproktitischen Abscesses. Eine prospektive Analyse bei 122 Patienten. Chirurg 61:53–58
Badgwell BD, Chang GJ, Rodriguez-Bigas MA et al (2009) Management and outcomes of anorectal infection in the cancer patient. Ann Surg Oncol 16:2752–2758
Barker JA, Conway AM, Hill J (2011) Supralevator fistula-in-ano in tuberculosis. Colorectal Dis 13:210–214
Buchan R, Grace RH (1973) Anorectal suppuration: the results of treatment and the factors influencing the recurrence rate. Br J Surg 60:537–540
Chrabot CM, Prasad ML, Abcarian H (1983) Recurrent anorectal abscesses. Dis Colon Rectum 26:105–108
Chung CC, Choi CL, Kwok SP et al (1997) Anal and perianal tuberculosis: a report of three cases in 10 years. J R Coll Surg Edinb 42:189–190
Conole FD (1967) The significance of the anal gland in the pathogenesis of anorectal abszess and fistula. Am J Proctol 18:232–238
Coremans G, Margaritis V, Van Poppel HP et al (2005) Actinomycosis, a rare and unsuspected cause of anal fistulous abscess: report of three cases and review of the literature. Dis Colon Rectum 48:575–581
Cox SW, Senagore AJ, Luchtefeld MA, Mazier WP (1997) Outcome after incision and drainage with fistulotomy for ischiorectal abscess. Am Surg 63:686–689
San Ildefonso Pereira A de, Maruri Chimeno I, Facal Alvarez C et al (2002) Bacteriology of anal fistulae. Rev Esp Enferm Dig 94:533–536
Delikoukos S, Zacharoulis D, Hatzitheofilou C (2005) Perianal abscesses due to ingested foreign bodies. Int J Clin Pract 59:856–857
Devaraj B, Khabassi S, Cosman BC (2011) Recent smoking is a risk factor for anal abscess and fistula. Dis Colon Rectum 54:681–685
Di Falco G, Guccione C, D’Annibale A et al (1986) Fournier’s gangrene following a perianal abscess. Dis Colon Rectum 29:582–585
Doublali M, Chouaib A, Elfassi MJ et al (2010) Perianal abscesses due to ingested foreign bodies. J Emerg Trauma Shock 3:395–397
Eisenhammer S (1978) The final evaluation and classification of the surgical treatment of the primary anorectal cryptoglandular intermuscular (intersphincteric) fistulous abscess and fistula. Dis Colon Rectum 21:237–254
Eisenhammer S (1956) The internal anal sphincter and the anorectal abscess. Surg Gynecol Obstet 501–506
Eisenhammer S (1958) A new approach to the anorectal fistulous abscess based on the hugh intermuscular lesion. Surg Gynecol Obstet 595–599
El-Dhuwaib Y, Ammori BJ (2003) Perianal abscess due to Neisseria gonorrhoeae: an unusual case in the post-antibiotic era. Eur J Clin Microbiol Infect Dis 22:422–423
Epstein J, Giordano P (2005) Endoanal ultrasound-guided needle drainage of intersphincteric abscess. Tech Coloproctol 9:67–69
Fucini C (1991) One stage treatment of anal abscesses and fistulas. A clinical appraisal on the basis of two different classifications. Int J Colorectal Dis 6:12–16
Garg PK, Jain BK (2011) Seton drainage in high anal fistula. Int J Colorectal Dis. online first
Gemsenjager E (1989) Zur Chirurgie kryptoglandulärer anorectaler Fisteln und Abszesse – Mit besonderer Berücksichtigung komplizierter Infekte. Chirurg 60:867–872
Ghoneim AT, McGoldrick J, Blick PW et al (1981) Aerobic and anaerobic bacteriology of subcutaneous abscesses. Br J Surg 68:498–500
Golligher JC, Ellis M, Pissidis AG (1967) A critique of anal glandular infection in the aetiology and treatment of idiopathic anorectal abscesses and fistulas. Br J Surg 54:977–983
Grace RH, Harper IA, Thompson RG (1982) Anorectal sepsis: microbiology in relation to fistula-in-ano. Br J Surg 69:401–403
Gupta PJ (2005) A study of suppurative pathologies associated with chronic anal fissures. Tech Coloproctol 9:104–107
Hamadani A, Haigh PI, Liu IL, Abbas MA (2009) Who is at risk for developing chronic anal fistula or recurrent anal sepsis after initial perianal abscess? Dis Colon Rectum 52:217–221
Hämäläinen KP, Sainio AP (1998) Incidence of fistulas after drainage of acute anorectal abscesses. Dis Colon Rectum 41:1357–1361; discussion 1361–1362
Hebjorn M, Olsen O, Haakansson T, Andersen B (1987) A randomized trial of fistulotomy in perianal abscess. Scand J Gastroenterol 22:174–176
Held D, Khubchandani I, Sheets J et al (1986) Management of anorectal horseshoe abscess and fistula. Dis Colon Rectum 29:793–797
Henrichsen S, Christiansen J (1986) Incidence of fistula-in-ano complicating anorectal sepsis: a prospective study. Br J Surg 73:371–372
Herr CH, Williams JC (1994) Supralevator anorectal abscess presenting as acute low back pain and sciatica. Ann Emerg Med 23:132–135
Ho YH, Tan M, Chui CH et al (1997) Randomized controlled trial of primary fistulotomy with drainage alone for perianal abscesses. Dis Colon Rectum 40:1435–1438
Hoffmann JC, Fischer I, Hohne W et al (2004) Methodological basis for the development of consensus recommendations. Z Gastroenterol 42:984–986
Hübner N-O, Assadian O, Kramer A (2007) Indikationen zur Wundantisepsis. GMS Krankenhhyg Interdiszip 2:1–4
Hübner N-O, Assadian O, Müller G, Kramer A (2007) Anforderungen an die Wundreinigung mit Wasser. GMS Krankenhhyg Interdiszip 2:1–4
Isbister WH (1995) Fistula in ano: a surgical audit. Int J Colorectal Dis 10:94–96
Isbister WH (1987) A simple method for the management of anorectal abscess. ANZ J Surg 57:771–774
Joos AK, Bussen D, Herold A (2009) Abszess, Analfistel, Analfissur. Allg Viszeralchirurg. up2date online first
Klosterhalfen B, Offner F, Vogel P, Kirkpatrick CJ (1991) Anatomic nature and surgical significance of anal sinus and anal intramuscular glands. Dis Colon Rectum 34:156–160
Knoefel WT, Hosch SB, Hoyer B, Izbicki JR (2000) The initial approach to anorectal abscesses: fistulotomy is safe and reduces the chance of recurrences. Dig Surg 17:274–278
Koukouras D, Kallidonis P, Panagopoulos C et al (2011) Fournier’s gangrene, a urologic and surgical emergency: presentation of a multi-institutional experience with 45 cases. Urol Int 86:167–172
Kramer A, Müller G, Assadian O (2006) Indikationen und Wirkstoffauswahl zur antiseptischen Therapie sekundär heilender Wunden. GMS Krankenhhyg Interdiszip 1:1–11
Kyle S, Isbister WH (1990) Management of anorectal abscesses: comparison between traditional incision and packing and de Pezzer catheter drainage. ANZ J Surg 60:129–131
Li D, Yu B (1997) Primary curative incision in the treatment of perianorectal abscess. Zhonghua Wai Ke Za Zhi 35:539–540
Lilius HG (1968) Fistula-in-ano, an investigation of human foetal anal ducts and intramuscular glands and a clinical study of 150 patients. Acta Chir Scand Suppl 383:7–88
Llera JL, Levy RC (1985) Treatment of cutaneous abscess: a double-blind clinical study. Ann Emerg Med 14:15–19
Lohsiriwat V, Yodying H, Lohsiriwat D (2011) Incidence and factors influencing the development of fistula-in-ano after incision and drainage of perianal abscesses. J Med Assoc Thai 93:61–65
Lunniss PJ, Faris B, Rees HC et al (1993) Histological and microbiological assessment of the role of microorganisms in chronic anal fistula. Br J Surg 80:1072
Lunniss PJ, Phillips RK (1994) Surgical assessment of acute anorectal sepsis is a better predictor of fistula than microbiological analysis. Br J Surg 81:368–369
Macfie J, Harvey J (1977) The treatment of acute superficial abscesses: a prospective clinical trial. Br J Surg 64:264–266
Magdeburg R, Grobholz R, Dornschneider G et al (2008) Perianal abscess caused by Actinomyces: report of a case. Tech Coloproctol 12:347–349
Makowiec F, Jehle EC, Becker HD, Starlinger M (1997) Perianal abscess in Crohn’s disease. Dis Colon Rectum 40:443–450
Malik AI, Nelson H, Tou S (2007) Incision and drainage of perianal abscess with or without treatment of anal fistula (Protocol). Cochrane Database Syst Rev 4:CD006827
Malik AI, Nelson H, Tou S (2010) Incision and drainage of perianal abscess with or without treatment of anal fistula (Review). Cochrane Database Syst Rev 4:CD006827
Mardini HE, Schwartz DA (2007) Treatment of perianal fistula and abscess: Crohn’s and non-Crohn’s. Curr Treat Options Gastroenterol 10:211–220
Maruyama R, Noguchi T, Takano M et al (2000) Usefulness of magnetic resonance imaging for diagnosing deep anorectal abscesses. Dis Colon Rectum 43:2–5
McElwain JW, MacLean MD, Alexander RM et al (1975) Anorectal problems: experience with primary fistulectomy for anorectal abscess, a report of 1,000 cases. Dis Colon Rectum 18:646–649
Millan M, Garcia-Granero E, Esclapez P et al (2006) Management of intersphincteric abscesses. Colorectal Dis 8:777–780
Mitalas LE, Wijk JJ van, Gosselink MP et al (2010) Seton drainage prior to transanal advancement flap repair: useful or not? Int J Colorectal Dis 25:1499–1502
Müller J-S, Meyer F (2004) Procedere chirurgischer Infektionen an Anus, Rektum und Perianalregion. Viszeralchirurgie 39:207–214
Nelson R (2002) Anorectal abscess fistula: what do we know? Surg Clin North Am 82:1139–1151, v–vi
Nicholls G, Heaton ND, Lewis AM (1990) Use of bacteriology in anorectal sepsis as an indicator of anal fistula: experience in a distinct general hospital. J R Soc Med 83:625–626
Nomikos IN (1997) Anorectal abscesses: need for accurate anatomical localization of the disease. Clin Anat 10:239–244
Nunoo-Mensah JW, Balasubramaniam S, Wasserberg N et al (2006) Fistula-in-ano: do antibiotics make a difference? Int J Colorectal Dis 21:441–443
Oliver I, Lacueva FJ, Perez Vicente F et al (2003) Randomized clinical trial comparing simple drainage of anorectal abscess with and without fistula track treatment. Int J Colorectal Dis 18:107–110
Ommer A, Athanasiadis S, Happel M et al (1999) Die chirurgische Behandlung des anorektalen Abszesses. Sinn und Unsinn der primären Fistelsuche. Coloproctology 21:161–169
Ommer A, Herold A, Berg E et al (2011) S3-Leitlinie: Kryptoglanduläre Analfisteln. AWMF online http://www.awmf.org/leitlinien/detail/ll/088-003.html
Ommer A, Herold A, Berg E et al (2011) S3-Leitlinie: Kryptoglanduläre Analfisteln. Coloproctology 33:295–324
Ommer A, Herold A, Berg E et al (2011) S3-Leitlinie: Kryptoglanduläre Analfisteln. Dtsch Arztebl Int 108(42):707–713
Onaca N, Hirshberg A, Adar R (2001) Early reoperation for perirectal abscess: a preventable complication. Dis Colon Rectum 44:1469–1473
Parks AG (1961) Pathogenesis and treatment of fistula-in-ano. Br Med J 463–469
Parks AG, Gordon PH, Hardcastle JD (1976) A classification of fistula-in-ano. Br J Surg 63:1–12
Parks AG, Stitz RW (1976) The treatment of high fistula-in-ano. Dis Colon Rectum 19:487–499
Parks AG, Thomson JP (1973) Intersphincteric abscess. Br Med J 2:537–539
Phillips B, Ball C, Sackett D et al (2009) Oxford Centre for Evidence-based medicine – levels of evidence. http://www.cebm.net/index.aspx?o=1025]
Quah HM, Tang CL, Eu KW et al (2006) Meta-analysis of randomized clinical trials comparing drainage alone vs primary sphincter-cutting procedures for anorectal abscess-fistula. Int J Colorectal Dis 21:602–609
Ramanujam PS, Prasad ML, Abcarian H, Tan AB (1984) Perianal abscesses and fistulas. A study of 1023 patients. Dis Colon Rectum 27:593–597
Read DR, Abcarian H (1979) A prospective survey of 474 patients with anorectal abscess. Dis Colon Rectum 22:566–568
Rickard MJ (2005) Anal abscesses and fistulas. ANZ J Surg 75:64–72
Rizzo JA, Naig AL, Johnson EK (2010) Anorectal abscess and fistula-in-ano: evidence-based management. Surg Clin North Am 90:45–68, Table of Contents
Sailer M, Fuchs KH, Reith HB, Thiede A (2000) Chirurgische Proktologie (Teil 2). Zentralbl Chir 125:W23–W30
Schmiegel W, Pox C, Reinacher-Schick A et al (2008) S3-Leitlinie „Kolorektales Karzinom“. Z Gastroenterol 46:1–73
Schouten WR, Vroonhoven TJ van (1991) Treatment of anorectal abscess with or without primary fistulectomy. Results of a prospective randomized trial. Dis Colon Rectum 34:60–63
Scoma JA, Salvati EP, Rubin RJ (1974) Incidence of fistulas subsequent to anal abscesses. Dis Colon Rectum 17:357–359
Seow-Choen F, Hay AJ, Heard S, Phillips RK (1992) Bacteriology of anal fistulae. Br J Surg 79:27–28
Seow-Choen F, Ho JM (1994) Histoanatomy of anal glands. Dis Colon Rectum 37:1215–1218
Seow-Choen F, Leong AF, Goh HS (1993) Results of a policy of selective immediate fistulotomy for primary anal abscess. ANZ J Surg 63:485–489
Serour F, Gorenstein A (2006) Characteristics of perianal abscess and fistula-in-ano in healthy children. World J Surg 30:467–472
Shafer AD, McGlone TP, Flanagan RA (1987) Abnormal crypts of Morgagni: the cause of perianal abscess and fistula-in-ano. J Pediatr Surg 22:203–204
Shukla HS, Gupta SC, Singh G, Singh PA (1988) Tubercular fistula in ano. Br J Surg 75:38–39
Sözener U, Gedik E, Kessaf Aslar A et al (2011) Does adjuvant antibiotic treatment after drainage of anorectal abscess prevent development of anal fistulas? A randomized, placebo-controlled, double-blind, multicenter study. Dis Colon Rectum 54:923–929
Stelzner F (1986) Komplizierte Anorektalabszesse und Fisteln. Chirurg 57:297–303
Stewart MP, Laing MR, Krukowski ZH (1985) Treatment of acute abscesses by incision, curettage and primary suture without antibiotics: a controlled clinical trial. Br J Surg 72:66–67
Tang CL, Chew SP, Seow-Choen F (1996) Prospective randomized trial of drainage alone vs. drainage and fistulotomy for acute perianal abscesses with proven internal opening. Dis Colon Rectum 39:1415–1417
Thomson JP, Parks AG (1979) Anal abscesses and fistulas. Br J Hosp Med 21:413–414, 418, 420–422. (passim)
Tonkin DM, Murphy E, Brooke-Smith M et al (2004) Perianal abscess: a pilot study comparing packing with nonpacking of the abscess cavity. Dis Colon Rectum 47:1510–1514
Toyonaga T, Matsushima M, Sogawa N et al (2006) Postoperative urinary retention after surgery for benign anorectal disease: potential risk factors and strategy for prevention. Int J Colorectal Dis 21:676–682
Toyonaga T, Matsushima M, Tanaka Y et al (2007) Microbiological analysis and endoanal ultrasonography for diagnosis of anal fistula in acute anorectal sepsis. Int J Colorectal Dis 22:209–213
Ulug M, Gedik E, Girgin S et al (2010) The evaluation of bacteriology in perianal abscesses of 81 adult patients. Braz J Infect Dis 14:225–229
Vasilevsky CA, Gordon PH (1984) The incidence of recurrent abscesses or fistula-in-ano following anorectal suppuration. Dis Colon Rectum 27:126–130
Weber E, Buchmann P (1982) Eröffnung anorectaler Abszesse – mit oder ohne Fistelspaltung. Chirurg 53:270–272
Whiteford MH (2007) Perianal abscess/fistula disease. Clin Colon Rectal Surg 20:102–109
Whiteford MH, Kilkenny J 3rd, Hyman N et al (2005) Practice parameters for the treatment of perianal abscess and fistula-in-ano (revised). Dis Colon Rectum 48:1337–1342
Whitehead SM, Leach RD, Eykyn SJ, Phillips I (1982) The aetiology of perirectal sepsis. Br J Surg 69:166–168
Yano T, Asano M, Matsuda Y et al (2010) Prognostic factors for recurrence following the initial drainage of an anorectal abscess. Int J Colorectal Dis 25:1495–1498
Yilmazlar T, Ozturk E, Ozguc H et al (2010) Fournier’s gangrene: an analysis of 80 patients and a novel scoring system. Tech Coloproctol 14:217–223
Zaheer S, Reilly WT, Pemberton JH, Ilstrup D (1998) Urinary retention after operations for benign anorectal diseases. Dis Colon Rectum 41:696–704
Zbar AP, Armitage NC (2006) Complex perirectal sepsis: clinical classification and imaging. Tech Coloproctol 10:83–93
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Ommer, A., Herold, A., Berg, E. et al. S3-Leitlinie: Analabszess. coloproctology 33, 378–392 (2011). https://doi.org/10.1007/s00053-011-0225-9
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DOI: https://doi.org/10.1007/s00053-011-0225-9