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Crustacean neuropeptides

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Abstract

Crustaceans have long been used for peptide research. For example, the process of neurosecretion was first formally demonstrated in the crustacean X-organ–sinus gland system, and the first fully characterized invertebrate neuropeptide was from a shrimp. Moreover, the crustacean stomatogastric and cardiac nervous systems have long served as models for understanding the general principles governing neural circuit functioning, including modulation by peptides. Here, we review the basic biology of crustacean neuropeptides, discuss methodologies currently driving their discovery, provide an overview of the known families, and summarize recent data on their control of physiology and behavior.

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Acknowledgments

This work was supported through institutional funds provided by Mount Desert Island Biological Laboratory.

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Authors and Affiliations

  1. Program in Neuroscience, John W. and Jean C. Boylan Center for Cellular and Molecular Physiology, Mount Desert Island Biological Laboratory, Old Bar Harbor Road, P.O. Box 35, Salisbury Cove, ME, 04672, USA

    Andrew E. Christie

  2. Department of Chemistry, Bowdoin College, 6600 College Station, Brunswick, ME, 04011, USA

    Elizabeth A. Stemmler

  3. Department of Biology, Bowdoin College, 6500 College Station, Brunswick, ME, 04011, USA

    Patsy S. Dickinson

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Correspondence to Andrew E. Christie.

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Christie, A.E., Stemmler, E.A. & Dickinson, P.S. Crustacean neuropeptides. Cell. Mol. Life Sci. 67, 4135–4169 (2010). https://doi.org/10.1007/s00018-010-0482-8

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