Abstract
Six bioactive alkaloids, aristolactam B(1), piperolactam A(2), aristolactam A(3), norcepharadione B(4), cepharadione B(5) and splendidine(6) were isolated by bioactivity-guided fractionation of a methanolic extract of the aerial part ofHouttuynia cordata. Several of them exhibited significant cytotoxicity against five human tumor cell lines (A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15)in vitro.
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Kim, SK., Ryu, S.Y., No, J. et al. Cytotoxic alkaloids fromHouttuynia cordate . Arch Pharm Res 24, 518–521 (2001). https://doi.org/10.1007/BF02975156
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DOI: https://doi.org/10.1007/BF02975156