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Controlled release of drugs from CD polymers substituted with ionic groups

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Abstract

Various disinfecting drugs (ethacridine lactate, methylene blue, gentian violet, brilliant green, fuchsin acid, cetylpyridinium chloride) were incorporated into CD bead polymers substituted with carboxymetbyl groups and a retarded release rate was measured. These polymers were successfully used as sustained release wound powders as well as in chewing gum formulations.

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References

  1. Szejtli, J.; Puetter, S., Inclusion complexes of polymerized cyclodextrins with pharmaceutical drugs, Eur. Pat. Appl. 575976 (1993)

  2. Szejtli, J.; Puetter, S., Chewing gum compositions, Eur. Pat. Appl. 575977 (1993)

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Authors and Affiliations

  1. Cyclolab R&D Lab., Ltd., P.O. Box 435, H-1525, Budapest, Hungary

    Fenyvesi É., Ujházy A. & Szejtli J.

  2. Medice Chem. pharm. Fabrik, Pütter GmBH, P.O. Box 2063, D-58638, Iserlohn, Germany

    Potter S. & Gan T. G.

Authors
  1. Fenyvesi É.
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  2. Ujházy A.
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  3. Szejtli J.
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  4. Potter S.
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  5. Gan T. G.
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Fenyvesi, É., Ujházy, A., Szejtli, J. et al. Controlled release of drugs from CD polymers substituted with ionic groups. J Incl Phenom Macrocycl Chem 25, 185–189 (1996). https://doi.org/10.1007/BF01041566

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  • DOI: https://doi.org/10.1007/BF01041566

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