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Outcome of pregnancy in a hypothyroid woman with resistance to thyroid hormone treated with triiodothyronine

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Abstract

Epidemiological and research data have shown the significant role of maternal thyroid hormone in fetal neurologic development. It has been suggested that maternal hypothyroxinemia is potentially damaging for the neurodevelopment of the fetus, independently of T3 levels. We present a pregnant woman with resistance to thyroid hormone and iatrogenic hypothyroidism who was treated with triiodothyronine during the whole pregnancy. Even though maternal hypothyroxinemia was severe the children showed a normal neuropsychological development.

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Authors and Affiliations

  1. Department of Endocrinology and Nutrition, General Hospital of Alicante, Alicante, Spain

    E. Boix Carreño, A. Picó & A. López

  2. Department of Pediatrics, General Hospital of Alicante, Alicante, Spain

    M. Zapico

  3. Department of Clinical Chemistry, General Hospital of Alicante, Alicante, Spain

    M. Mauri

  4. Partida Alzabares Alto. Polígono 1. 146, 03290, Elche, Alicante, Spain

    E. Boix Carreño

Authors
  1. E. Boix Carreño
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  2. A. Picó
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  3. M. Zapico
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  4. A. López
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  5. M. Mauri
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Correspondence to E. Boix Carreño.

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Boix Carreño, E., Picó, A., Zapico, M. et al. Outcome of pregnancy in a hypothyroid woman with resistance to thyroid hormone treated with triiodothyronine. J Endocrinol Invest 30, 253–255 (2007). https://doi.org/10.1007/BF03347434

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  • DOI: https://doi.org/10.1007/BF03347434

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