Abstract
In 6 patients receiving hepatic artery infusion chemotherapy for liver metastases, planar and single-photon emission computed tomography (SPECT) images of the abdomen were obtained after intravenous injection of99mTc-phytate, and intra-catheter injection of99mTc-MAA in the same geometrical settings. With this method, the three-dimensional intra- and extra-hepatic distribution of the agents during hepatic artery infusion chemotherapy can be evaluated.
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Yang PJ, Thrall JH, Ensminger WD, et al: Perfusion scintigraphy (Tc-99m MAA) during surgery for placement of chemotherapy catheter in hepatic artery: concise communication.J Nucl Med 23: 1066–1069, 1982
Ziessman HA, Thrall JH, Gyves JW, et al: Quantitative hepatic arterial perfusion scintigraphy and starch microsphere in cancer chemotherapy.J Nucl Med 24: 871–875, 1983
Ziessman HA, Thrall JH, Yang PJ, et al: Hepatic arterial perfusion scintigraphy with Tc-99m MAA.Radiology 152: 167–172, 1984
Miller DL, Schneider PD, Gianola FJ, et al: Assessment of perfusion patterns during hepatic artery infusion chemotherapy: E0E-13CT and99mTc-MAA Scintigraphy.AJR 143: 827–831, 1984
Bledin AG, Kim EE, Chuang VP, et al: Changes of arterial blood flow patterns during infusion chemotherapy, as monitored by intra-arterially injected technetium-99m macroaggregated albumin.Brit J Radiology 57: 197–203, 1984
Ziessman HA, Gyves GW, Juni JE, et al: Atlas of hepatic arterial perfusion scintigraphy.Clin Nucl Med 10: 675–681, 1985
Kim EE, Haynie TP: Role of nuclear medicine in chemotherapy of malignant lesions.Seminars Nucl Med 15: 12–20, 1985
Gyves JW, Ziessman HA, Ensminger WD: Definition of hepatic tumor microcirculation by single photon emission computed tomography (SPECT).J Nucl Med 25: 972–977, 1984
Goldberg JA, Bradam MS, Kerr DJ, et al: Single photon emission computed tomographic studies (SPECT) of hepatic arteries perfusion scintigraphy (HAPS) in patients with colorectal liver metastases: improved tumor targeting by microspheres with angiotensin II.Nucl Med Communications 8: 1025–1032, 1987
Chang LT: A method for attenuation correction in radionuclide computed tomography.IEEE Trans Nucl Sci NS-25: 638–643, 1978
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Suzuki, Y., Kobayashi, S. & Yasuda, S. Application of single-photon emission computed tomography (SPECT) with99mTc-MAA in evaluation of perfusion patterns during hepatic infusion chemotherapy. Ann Nucl Med 5, 123–126 (1991). https://doi.org/10.1007/BF03164625
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DOI: https://doi.org/10.1007/BF03164625