Abstract
A study was undertaken to determine the average values for elements in normal human brain (11 individuals, age group 65–75). Twelve brain parts were selected from both hemispheres. Determinations were carried out by NAA and ICP-AES. The main elements (Na, K, Mg, Ca, Fe, P, S) and trace elements (Al, B, Co, Cr, Cu, Mn, Ni, Pb, Zn) were investigated. Quality control was ensured by using NBS Bovine Liver SRM. The results obtained with independent methods were compared, and the data show a good correlation. On the basis of these investigations, the regional distribution of elements can be given.
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References
E. Andrási, M. Mohos, L. Bezur, and Zs. Molnár,Trace Element Analytical Chemistry in Medicine and Biology, vol. 5., Walter de Gruyter, Berlin, New York, p. 261, 1988.
T. Bereznai, D. Bódizs, and G. Keömley,J. Radioanal. Chem. 36 (1977).
L. Bezur, L. Ernyei, and E. Pungor, Abstracts, Winter Conference on Plasma and Laser Spectrochemistry, Lyon, p. 241 (1987).
W. D. Ehmann, W. R. Markesbery, M. Alauddin, T. I. M. Hossain, and E. H. Brubaker,Neurotoxicology 7/1 197–206 (1986).
C. M. Thompson, W. R. Markesbery, W. D. Ehmann, Y-X. Mao, and D. E. Vance,Neurotoxicology 9/1 1–8 (1988).
H. Duflou, W. Maenhaut, and J. De Reuck,Trace Element Analytical Chemistry in Medicine and Biology, vol. 5., Walter de Gruyter, Berlin, New York, p. 483, 1988.
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Andrási, E., Nádasdi, J., Molnar, Z. et al. Determination of main and trace element contents in human brain by NAA and ICP-AES methods. Biol Trace Elem Res 26, 691–698 (1990). https://doi.org/10.1007/BF02992725
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DOI: https://doi.org/10.1007/BF02992725