Abstract
Objective
To deepen understanding of hemodynamics in the femoral head, i.e., the essential factor in clarifying pathogenesis of hip disorders, this study examined blood flow and blood volume in the femoral heads of healthy adults, and their changes with age, by using positron emission tomography (PET).
Methods
In 16 healthy adult males (age: 20–78 years old, mean age: 42 years), blood flow was measured by means of the H2 15O dynamic study method, and blood volume was measured by means of the15O-labeled carbon monoxide bolus inhalations methods.
Results
Blood flow was 1.68–6.47 ml/min/100g (mean±SD: 3.52±1.2), and blood volume was 1.67–6.03 ml/100 g (mean±SD: 3.00±1.27). Blood flow significantly decreased (p<0.01) with age, and blood volume significantly increased (p<0.05).
Conclusion
PET was useful in the measurement of blood flow and blood volume in the femoral heads. With age, physiological hemodynamic changes also increased in femoral heads.
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Kubo, T., Kimori, K., Nakamura, F. et al. Blood flow and blood volume in the femoral head of healthy adults according to age: Measurement with positron emission tomography (PET). Ann Nucl Med 15, 231–235 (2001). https://doi.org/10.1007/BF02987837
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DOI: https://doi.org/10.1007/BF02987837