Abstract
A series of 2,3-dihydroindole-2-thiones was evaluated forin vitro antimycobacterial activity againstMycobacterium tuberculosis, M. kansasii, M. fortuitum, two strains ofM. intracellulare and three strains ofM. avium. 2,3-Dihydro-1-methyl-2-thioxoindole-3-one and 2,3-dihydro-1-butyl-2-thioxoindole-3-one were the most active substances against potentially pathogenic strains, being more active than isoniazide.
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The work was a part of the research project no. MSM 0021 620 822 of theMinistry of Education, Youth and Sports of the Czech Republic.
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Waisser, K., Heinisch, L., Šlosárek, M. et al. New antimycobacterial 2,3-dihydro-1-alkylindole-2-thiones. Folia Microbiol 51, 25–26 (2006). https://doi.org/10.1007/BF02931445
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DOI: https://doi.org/10.1007/BF02931445