Abstract
Abdominal neuroblastoma is reviewed in terms of its diagnosis, including in utero, at birth, and through infancy into childhood. Age at diagnosis remains the best predictor of survival, with infants under 1 year of age having almost 100% cure. Ultrasonography and magnetic resonance imaging (MRI) are the recommended diagnostic modalities to stage the abdominal primary, although computed tomography (CT) (including myelography) is still widely and efficiently used. Examples are given of each stage.
Similar content being viewed by others
References
Evans AE,et al.: A proposed staging system for children with neuroblastoma.Cancer 27:374, 1971
Nickerson HJ,et al.: Comparison of stage IV and IV-S neuroblastoma in the first year of life.Med Pediatr Oncol 13:261, 1985
Paul SR,et al.: Stage IV neuroblastoma in infants. Long term survival.Cancer 67:1493, 1991
Brodeur GM,et al.: International criteria for diagnosis, staging and response to treatment in patients with neuroblastoma.J Clin Oncol 6:1874, 1988
Kretschmar CS,et al.: Improved prognosis for infants with stage IV neuroblastoma.J Clin Oncol 2:799, 1984
Bourhis J,et al.: N-myc genomic content and DNA ploidy in stage IV-S neuroblastoma.J Clin Oncol 9:1371, 1991
Garvin J,et al.: N-myc oncogene impression and amplification in metastatic lesions of stage IV-S neuroblastoma.Cancer 65:2572, 1990
Bousvaros A,et al.: Imaging of neuroblastoma: An overview.Pediatr Radiol 16:89, 1986
Baker ME,et al.: The association of neuroblastoma and myoclonic encephalopathy: An imaging approach.Pediatr Radiol 15:185, 1984
Murphy SB,et al.: Do children benefit from mass screening for neuroblastoma?Lancet 337:344, 1991
Fletcher BD,et al.: Abdominal neuroblastoma: MRI and tissue characterization.Radiology 155:699, 1985
Benz-Bohm G,et al.: Bone marrow metastases of neuroblastoma: MRT in comparison with bone marrow cytology and mIBG scintigraphy.ROFO 152:523, 1990
Couanet D,et al.: Bone marrow metastases in children’s neuroblastoma studied by MRI.Prog Clin Biol Res 271:547, 1988
Kornreich L,et al.: Neuroblastoma: Evaluation with contrast enhanced MR imaging.Pediatr Radiol 21:566, 1991
Petrus LV, Hall TR, Boechat MI, Westra SJ, Curran JG, Steckel RJ, Kangarloo H: The pediatric patient with suspected adrenal neoplasm: Which radiological test to use?Med Pediatr Oncol 20:53–57, 1992
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Berdon, W.E., Ruzal-Shapiro, C., Abramson, S.J. et al. The diagnosis of abdominal neuroblastoma: Relative roles of ultrasonography, CT, and MRI. Urol Radiol 14, 252–262 (1992). https://doi.org/10.1007/BF02926942
Issue Date:
DOI: https://doi.org/10.1007/BF02926942