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The association of neuroblastoma and myoclonic encephalopathy: an imaging approach

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Abstract

Myoclonic encephalopathy is a unique clinical syndrome of infants and children that is associated with a neurogenic tumor of ganglion-cell origin in approximately half of cases. A review of the literature as well as our personal experience with two recent infants suggests an imaging approach that includes chest radiography and abdominal computed tomography (CT). Ultrasonography, neck CT, and chest CT myelography may be required in selected patients. An expedient clinical and imaging evaluation of infants and children with opsomyoclonus is important to detect those patients with neurogenic tumors.

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Authors and Affiliations

  1. Department of Radiology, Duke University Medical Center, Box 3834, 27710, Durham, NC, USA

    M. E. Baker, D. R. Kirks, M. Korobkin & James D. Bowie

  2. Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA

    H. C. Filston

Authors
  1. M. E. Baker
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  2. D. R. Kirks
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  3. M. Korobkin
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  4. James D. Bowie
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  5. H. C. Filston
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Dr. Baker is a Regular Clinical Fellow of the American Cancer Society

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Baker, M.E., Kirks, D.R., Korobkin, M. et al. The association of neuroblastoma and myoclonic encephalopathy: an imaging approach. Pediatr Radiol 15, 185–189 (1985). https://doi.org/10.1007/BF02388608

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  • DOI: https://doi.org/10.1007/BF02388608

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