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Continuous monitoring of mixed venous oxygen saturation in septic shock

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Abstract

Fiberoptic pulmonary artery catheters provide a practical method for continuously measuring the amount of oxygen in mixed venous blood. To characterize the usefulness of mixed venous oxygen saturation in managing patients with sepsis, we performed serial hemodynamic measurements on 20 patients with documented septic shock. There was a highly significant positive correlation between increases or decreases of 5% or more in mixed venous oxygen saturation and corresponding changes in oxygen delivery (r = 0.95) and oxygen consumption (r = 0.96). Mixed venous oxygen saturation less than 65% was clinically unacceptable in patients with sepsis and was associated with a poor prognosis. In this study, measurement of mixed venous oxygen saturation was a valuable predictor of survival in patients with septic shock and provided a means of continuously monitoring the status of tissue oxygenation.

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Authors and Affiliations

  1. Department of Internal Medicine, Northeastern Ohio Universities College of Medicine, Rootstown, OH

    Darell Heiselman DO, FACA & Louis Cannon MD

  2. Department of Emergency Medicine, Northeastern Ohio Universities College of Medicine, Rootstown, OH

    Jeffrey Jones MD & Louis Cannon MD

Authors
  1. Darell Heiselman DO, FACA
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  2. Jeffrey Jones MD
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  3. Louis Cannon MD
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Heiselman, D., Jones, J. & Cannon, L. Continuous monitoring of mixed venous oxygen saturation in septic shock. J Clin Monitor Comput 2, 237–245 (1986). https://doi.org/10.1007/BF02851172

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  • DOI: https://doi.org/10.1007/BF02851172

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