Abstract
Primary anorectal melanoma is a rare malignancy with an extremely aggressive biological behaviour. The main clinical presentations are local symptoms such as rectal bleeding, anal mass or pain, or a change in bowel habits. The tumour is frequently mistaken for benign conditions as haemorrhoids or rectal polyps. Many treatments can be used: surgery, chemotherapy, radiotherapy, immunotherapy and even biotherapy. Despite this, the disease has a very poor prognosis and <10% of patients survive >5 years.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Bibliografía
Chang AE, Karnell LH, Menck HR. The national Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society. Cancer. 1998;83(8):1664–78.
Wanebo HJ, Woodruff JM, Farr GH, Quau SH. Anorectal melanoma. Cancer. 1981;47:1891–900.
Pantalone D, Taruffi F, Paolucci R, Liguori P, Rastrelli M, Andreoli F. Malignant melanoma of the rectum. Eur J Surg. 2000;166(7):583–4.
Werdin C, Limas C, Knodell RG. Primary malignant melanoma of the rectum. Evidence for origination from rectal mucosal melanocytes. Cancer. 1988;61(7):1364–70.
Weinstock MA. Epidemiology and prognosis of anorectal melanoma. Gastroenterology. 1993;104:174–8.
Cagir B, Whiteford MH, Topham A, et al. Changing epidemiology of anorectal melanoma. Dis Colon Rectum. 1999;42:1203–8.
Thibault C, Sagar P, Nivatvongs S, et al. Anorectal melanoma-An incurable disease?. Dis Colon Rectum. 1997; 40:661–8.
Brady MS, Kavolius JP, Quan SHQ. Anorectal melanoma. A 64-year experience at Memorial Sloan Kettering Cancer Center. Dis Colon Rectum. 1995;38:146–51.
Weyandt GH, Eggert AO, Houf M, Raulf F, Brocker EB, Becker JC. Anorectal melanoma: surgical management guidelines according to tumour thickness. Br J Cancer. 2003;89(11):2019–22.
Lens MB, Eisen TG. Systemic chemotherapy in the treatment of malignant melanoma. Expert Opin Pharmacother. 2003;4(12):2205–11.
Pavlick AC, Adams S, Fink MA, Bailes A. Novel therapeutic agents under investigation for malignant melanoma. Expert Opin Investig Drugs. 2003;(9):1545–58.
Kim KB, Sanguino AM, Hodges C, et al. Biochemotherapy in patients with metastasic anorectal mucosal melanoma. Cancer. 2004;100(7):1478–83.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Moreno, E.S., Morales, M.V., Búrdalo, G.S. et al. Melanoma primario de recto: una neoplasia infrecuente con una forma de presentación atípica. Clin Transl Oncol 7, 171–173 (2005). https://doi.org/10.1007/BF02708756
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02708756