Skip to main content
SpringerLink
Log in

Permeability changes of phospholipid vesicles caused by surfactants

  • Published:
Journal of the American Oil Chemists Society

Abstract

The partition coefficient at equilibrium of different surfactants between the aqueous phase and the lipid bilayer of small unilamellar vesicle (SUV) liposome has been determined. The release of the fluorescent agent 5-(6) carboxyfluorescein from the interior of liposomes, induced by a nonionic surfactant octylphenol ethoxylated with 10 units of ethylene oxide (Triton X-100), by two anionic surfactants — sodium dodecyl sulphate and sodium dodecyl ether sulphate — and by an amphoteric surfactant dodecyl betaine was studied at sub-solubilizing concentrations. The following increasing order of the partition coefficients obtained for each surfactant can be observed: Triton X-100 > sodium dodecyl ether sulphate > sodium dodecyl sulphate > dodecyl betaine. There was a strong positive association between coefficient of partition and the ability of the different surfactants to modify the permeability of liposomes. The importance of the presence of ethylene oxide units in the molecular structure of the surfactant in relation to alter the partition coefficient in front of SUV liposomes is indicated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Papahadjopoulos, D., inLiposomes and Their Uses in Biology and Medicine, Ann. New York Acad. Sci., 1978, pp. 1-462.

  2. Ostro M.J.,Scientific American 256:90 (1987).

    Article  Google Scholar 

  3. Hellenius A., and K. Simons,Biochim. Biophys. Acta 415:29(1975).

    Google Scholar 

  4. Uena M., C. Tanford and J.A. Reynolds,Biochemistry 23:3070 (1984).

    Article  Google Scholar 

  5. Enoch H.G., and P. Strittmatter,Proc. Natl. Acad. Sci. USA 76:145 (1979).

    Article  CAS  Google Scholar 

  6. Gerritsen W.J., A.J. Verkleij, R.F. Zwaal and L.L.Van Deenen,Eur. J. Biochem. 85:255(1978).

    Article  CAS  Google Scholar 

  7. Peterson S.W., S. Hanna and D.W. Deamer,Arch. Biochem. Biophys. 191:224(1978).

    Article  CAS  Google Scholar 

  8. Sunamoto J., K. Iwamoto, H. Ikeda and K. Furuse,Chem. Pharm. Bull 31:4230 (1983).

    CAS  Google Scholar 

  9. Sappey Marinier D., R. Letoublon and J. Delmau,J. ofLipid Res. 29:1237 (1988).

    Google Scholar 

  10. Thewalt J.L., and R.J. Cushley,Biochim. Biophys. Acta 905:329 (1987).

    Article  CAS  Google Scholar 

  11. Lichtenberg B.R., J. Robson and E.A. Dennis,Ibid. 737:285 (1983).

    CAS  Google Scholar 

  12. Helenius A., D.R. McCaslin, E. Fries and C. Tanford,Methods Enzymol 56:734 (1979).

    Article  CAS  Google Scholar 

  13. Alonso A.,R. Saez, A. Villena and F.M. Goñi,J. Membrane Biol. 67:55 (1982).

    Article  CAS  Google Scholar 

  14. Alonso A., R. Saez and F.M. Goni,FEBS Lett. 137:141 (1982).

    Article  CAS  Google Scholar 

  15. Jackson M.L., D. Schmidt, B.J. Lichtenberg, A. Litman and A.D. Albert,Biochemistry 21:4576 (1982).

    Article  CAS  Google Scholar 

  16. Schubert R., K. Beyer, H. Wolburg and K.M. Schmidt,Ibid. 25:5263 (1986).

    Article  CAS  Google Scholar 

  17. Lichtenberg D.,Biochim. Biophys. Acta 821:470 (1985).

    Article  CAS  Google Scholar 

  18. Parker C.A., inPhotoluminiscence of Solutions, Elsevier, New York, 1968, Chapter 4, pp. 303–396.

    Google Scholar 

  19. Weinstein J.N., E. Ralston, L.D. Leserman, R.D. Klausner, P. Dragsten, P. Henkart and R. Blumenthal, inLiposome Technology, Vol. III, edited by G. Gregoriadis, CRC Press, Boca Raton, 1986, pp. 183–205.

    Google Scholar 

  20. Lelkes P.I.,Ibid., pp. 225–247.

    Google Scholar 

  21. Gorii F.M., A. Urbaneja, J.L. Arrondo, A. Alonso, A. Durrani and D. Chapman,Eur. J. Biochem.160:659 (1986).

    Article  Google Scholar 

  22. Prado A., J.L. Arrondo, A. Villena, F.M. Goni and J.M. Macarulla,Biochim,. Biophys. Acta 733:163 (1983).

    Article  CAS  Google Scholar 

  23. Alonso A., M.A. Urbaneja, F.M. Goni, F.G. Carmona, F.G. Canovas and J. Gomez-Fernandez,Ibid. 902:237 (1987).

    Article  CAS  Google Scholar 

  24. Allen T.M., inLiposome Technology, Vol. I, edited by G. Gregoriadis, CRC Press, Boca Raton, 1986, pp. 110–120.

    Google Scholar 

  25. Ribosa I., M.T. Garcia, A. De la Maza and C. Trullás,Proc. J. Cam. Delerg., 1989, pp. 399–418.

  26. Barker, G., inSurfactants in Cosmetics, Surfactant Science Series, Vol. 16, edited by Martin M. Rieger, Marcel Dekker Inc., 1985, pp.14-16.

  27. Singleton W.S., M.S. Gray, M.L. Brown and J.L. White,J. Am, Oil Chem,. Soc. 42:53 (1965).

    Article  CAS  Google Scholar 

  28. Ralston E., L.M. Hjelmeland, R.D. Klausner, J.N. Weinstein and R. Blumenthal,Biochim. Biophys. Acta 649:133 (1981).

    Article  CAS  Google Scholar 

  29. Rigaud J.L., A. Bluzat and S. Buschlen, inPhysical Chemistry of Transmembrane Ion Motion, edited by G. Spach, Elsevier, Amsterdam, 1983, pp. 457–464.

    Google Scholar 

  30. Rigaud J.L., A. Bluzat and S. Buschlen,Biochem. Biophys. Res. Commun. 111:373 (1983).

    Article  CAS  Google Scholar 

  31. Szoka, F., and D. Papahadjopoulos, inLiposomes: Préparation,and Characterization, edited by C.G. Knight, Elsevier, Amsterdam, 1981, Chapter 30.

  32. Szoka F., F. Olson, T. Heath, W. Vail, E. Mayer and D. Papahad- jopoulos,Biochim. Biophys. Acta 601:559 (1890).

    Google Scholar 

  33. Allen R.J.L.,Biochem. J. 34:858 (1940).

    CAS  Google Scholar 

  34. Lunkenheimer K., and D. Wantke,Colloid and Polymer. Sci.259:354 (1981).

    Article  CAS  Google Scholar 

  35. Strauss G., inLiposome Technology, Vol. I, edited by G. Gregoriadis, CRC Press, Boca Raton, 1986, pp. 197–221.

    Google Scholar 

  36. Paternostre M.T., M. Roux and J.L. Rigaud,Biochemistry 27:2668 (1988).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Instituto de Tecnologia Quimica y Textil (C.S.I.C.), C/ Jorge Girona, 18-26, 08034, Barcelona, Spain

    A. de la Maza, J. Sanchez Leal, J. L. Parra, M. T. Garcia & I. Ribosa

Authors
  1. A. de la Maza
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Sanchez Leal
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. L. Parra
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M. T. Garcia
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. I. Ribosa
    View author publications

    You can also search for this author in PubMed Google Scholar

About this article

Cite this article

de la Maza, A., Sanchez Leal, J., Parra, J.L. et al. Permeability changes of phospholipid vesicles caused by surfactants. J Am Oil Chem Soc 68, 315–319 (1991). https://doi.org/10.1007/BF02657684

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02657684

Keywords

Search

Navigation