Abstract
Interstitial laser photocoagulation (ILP), which is a new method of low power thermal destruction of tumours by laser, was employed to treat laparoscopically 16 patients with symptomatic uterine leiomyomas who had declined laparotomy. The KTP/YAG laser, with wavelengths of 532 and 1064 nm, respectively, was employed. Holes were drilled in the myomas with a 600 μm quartz laser fibre employing the KTP component at 8 W and subsequent coagulation of the surrounding myoma tissue was accomplished during the withdrawal of the fibre over the course of 10–30 s but using the YAG component at 8 W. Further holes were bored 2 cm from the original one and the process repeated until the whole myoma had been treated. All but one patient became symptom-free and have remained so. Eleven were cured with or without residual scarring, one became pregnant before the myoma had completely disappeared, three were lost to follow-up and in one the treatment largely failed. The results are extremely promising and warrant further research.
Similar content being viewed by others
References
Breasted JH.The Edwin Smith Surgical Papyrus, Vol. 1. Chicago: University of Chicago, 1930
Hand JW, ter Haar G. Heating techniques in hyperthermia.Br J Radiol 1981,54:443–66
Gallinat A, Lueken RP. Addendum—current trends in the therapy of myomata. In: Lueken RP, Gallinat A (eds).Endoscopic Surgery in Gynecology. Hamburg: Demeter Verlag Gmbh, 1993: 69–71
Chapman R. Treatment of uterine myomas by interstitial hyperthermia.Gynaecological Endoscopy 1993,2:227–34
Bown SG. Phototherapy of tumours.World J Surg 1983,7:700–9
Masters A, Bown SG. Interstitial laser hyperthermia in the treatment of tumours.Lasers Med Sci 1990,5:129–35
Steger AC, Less WR, Walmsley K, Bown SG Interstitial laser hyperthermia: a new approach to local destruction of tumours.BMJ 1989,299:362–5
Amin Z, Donald JJ, Masters A et al. Hepatic metastases: interstitial laser photocoagulation with real time US monitoring and dynamic CT evaluation of treatment.Radiology 1993,187:339–47
Amin Z, Lees WR, Bown SG. Interstitial laser photocoagulation for the treatment of prostatic cancer.Br J Radiol 1993,66:1044–7
Roux FX, Merrienne L, Leriche B et al. Laser interstitial thermotherapy in stereotactical neurosurgeryLasers Med Sci 1992,7:121–6
Castro DJ, Lufkin RB, Saxton RE et al. Metastatic head and neck malignancy treated using MRI guided interstitial laser phototherapy: an initial case report.Laryngoscope 1992,102:26–32
Filicori M, Hall DA, Loughlin JS et al. A conservative approach to the management of uterine leiomyoma: pituitary desensitization by a luteinizing hormone-releasing hormone analogue.Am J Obstet Gynecol 1983,147:726–7
Buttram VC, Reiter RC. Uterine leiomyomata: etiology, symptomatology and management.Fertil Steril 1981,36:433–45
Semm K. Endocoagulation: a new field of endoscopy surgery.J Reprod Med 1976,16:195–203
Semm K. Tissue-puncher and loop-ligation—new aids for surgical-therapeutic pelviscopy (laparoscopy)= endoscopic intra-abdominal surgery.Endoscopy 1978,10:119–24
Semm K, Mettler L. Local infiltration of Ornithine 8-Vasopressin (POR 8) as a vasoconstrictive agent in surgical pelviscopy (applied to myoma enucleation, salpingotomy in cases of tubal pregnancy and peripheral salpingostomy.Endoscopy 1988,20:298–304
Semm K, Mettler L. Technical progress in pelvic surgery via operative laparoscopy.Am J Obstet Gynecol 1980,138:121–7
McLaughlin DS. Micro-laser myomectomy technique to enhance reproductive potential: a preliminary report.Lasers Surg Med 1982, 2:107–27
Donnez J, Gillerot S, Bourgonjon D et al. Neodymium-YAG laser hysteroscopy in large submucous fibroids.Fertil Steril 1990,54:999–1003
Goldfarb HA. Nd-YAG laser laparoscopic coagulation of symptomatic myomasJ Reprod Med 1992,37:636–8
Donnez J, Schrurs B, Gillerot S et al. Treatment of uterine fibroids with implants of gonadotrophin-releasing hormone agonist: assessment by hysterography.Gertil Steril 1989,51:947–50
West CP. LHRH analogues in the management of uterine fibroids, premenstrual syndrome and breast malignancies.Baillieres Clin Obstet Gynaecol 1988,2:689–709
Mitchell JP, Lumb GN, Dobbie AK.A Handbook of Surgical Diathermy, 2nd edn. Bristol: John Wright, 1978:23–5
Wilson EA, Yang F, Rees ED. Estradiol and progesterone binding in uterine leiomyomata and in normal uterine tissues.Obstet Gynecol 1980,55:20–4
West CP, Lumsden MA. Fibroids and menorrhagia.Baillieres Clin Obstet Gynaecol 1989,3:357–74
Amin Z, Buonaccorsi G, Mills T et al. Interstitial laser photocoagulation: evaluation of a 1320 nm Nd-YAG and an 805 nm diode laser: the significance of charring and the value of pre-charring the fibre tip.Lasers Med Sci 1993,8:113–20
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Chapman, R. Low power interstitial photocoagulation of uterine leiomyomas by KTP/YAG laser. Laser Med Sci 9, 37–46 (1994). https://doi.org/10.1007/BF02594183
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02594183